SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                ----------------

                                  SCHEDULE 13D
                                 (Rule 13d-101)



                 INFORMATION TO BE INCLUDED IN STATEMENTS FILED
                    PURSUANT TO RULE 13d-1(a) AND AMENDMENTS
                     THERETO FILED PURSUANT TO RULE 13d-2(a)



                              Halsey Drug Co., Inc.
           -----------------------------------------------------------
                                (Name of Issuer)

                     Common Stock, par value $0.01 per share
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                   4063691087
           -----------------------------------------------------------
                                 (CUSIP Number)

                                 David R. Ramsay
                              Care Capital II, LLC
                                47 Hulfish Street
                                    Suite 310
                               Princeton, NJ 08542
                            Tel. No.: (609) 683-8300
--------------------------------------------------------------------------------
            (Name, Address and Telephone Number of Person Authorized
                     to Receive Notices and Communications)

                                December 20, 2002
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)
--------------------------------------------------------------------------------

     If the filing  person has  previously  filed a statement on Schedule 13G to
report the  acquisition  that is the subject of this Schedule 13D, and is filing
this  schedule  because  of Rule  13d-1(e),  13d-1(f)  or  13d-1(g),  check  the
following box |_|

     The  information  required on the remainder of this cover page shall not be
deemed to be "filed"  for the purpose of Section 18 of the  Securities  Exchange
Act of 1934 or  otherwise  subject  to the  liabilities  of that  section of the
Exchange  Act but shall be subject to all other  provisions  of the Exchange Act
(however, see the Notes).



                                                             Page 2 of 16 pages
--------------------------------------------------------------------------------
(1)   Name of Reporting Persons:
      S.S. or I.R.S. Identification Nos. of above persons (entities only):
      Care Capital Investments II, LP
--------------------------------------------------------------------------------
(2)   Check the Appropriate Box if a Member of a Group (See Instructions)
      (a)  [x]
      (b)  [ ]

--------------------------------------------------------------------------------
(3)   SEC Use Only:

--------------------------------------------------------------------------------
(4)   Source of Funds (See Instructions):
      WC
--------------------------------------------------------------------------------
(5)   Check Box if Disclosure of Legal Proceedings is Required Pursuant to Items
      2(d) or 2(e): [ ]

--------------------------------------------------------------------------------
(6)   Citizenship or Place of Organization:
      Delaware
--------------------------------------------------------------------------------
NUMBER OF SHARES                    (7)   Sole Voting Power
BENEFICIALLY OWNED                        0
BY EACH REPORTING                  ---------------------------------------------
PERSON WITH                         (8)   Shared Voting Power
                                          14,705,882
                                   ---------------------------------------------
                                    (9)   Sole Dispositive Power
                                          0
                                   ---------------------------------------------
                                   (10)   Shared Dispositive Power
                                          14,705,882
                                   ---------------------------------------------

(11)  Aggregate Amount Beneficially Owned by Each Reporting Person:
      14,705,882
--------------------------------------------------------------------------------
(12)  Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares
      (See Instructions):     1
                           [x]
--------------------------------------------------------------------------------
(13)  Percent of Class Represented by Amount in Row (11):
      41.1%
--------------------------------------------------------------------------------
(14)  Type of Reporting Person (See Instructions):
      PN
--------------------------------------------------------------------------------

1    The Reporting Person disclaims ownership of 65,957,490 additional Shares,
     which it may be deemed to indirectly  beneficially  own, as described more
     fully in Items 4 and 5 below.



                                                              Page 3 of 16 pages
--------------------------------------------------------------------------------
(1)   Name of Reporting Persons:
      S.S. or I.R.S. Identification Nos. of above persons (entities only):
      Care Capital II, LLC
--------------------------------------------------------------------------------
(2)   Check the Appropriate Box if a Member of a Group (See Instructions)
      (a)  [x]
      (b)  [ ]

--------------------------------------------------------------------------------
(3)   SEC Use Only:

--------------------------------------------------------------------------------
(4)   Source of Funds (See Instructions):
      AF
--------------------------------------------------------------------------------
(5)   Check Box if Disclosure of Legal Proceedings is Required Pursuant to Items
      2(d) or 2(e): [ ]

--------------------------------------------------------------------------------
(6)   Citizenship or Place of Organization:
      Delaware
--------------------------------------------------------------------------------
NUMBER OF SHARES                    (7)   Sole Voting Power
BENEFICIALLY OWNED                        0
BY EACH REPORTING                  ---------------------------------------------
PERSON WITH                         (8)   Shared Voting Power
                                          14,705,882
                                   ---------------------------------------------
                                    (9)   Sole Dispositive Power
                                          0
                                   ---------------------------------------------
                                   (10)   Shared Dispositive Power
                                          14,705,882
                                   ---------------------------------------------

(11)  Aggregate Amount Beneficially Owned by Each Reporting Person:
      14,705,882
--------------------------------------------------------------------------------
(12)  Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares
      (See Instructions):     1
                           [x]
--------------------------------------------------------------------------------
(13)  Percent of Class Represented by Amount in Row (11):
      41.1%
--------------------------------------------------------------------------------
(14)  Type of Reporting Person (See Instructions):
      OO
--------------------------------------------------------------------------------

1    The Reporting Person disclaims ownership of 65,957,490 additional Shares,
     which it may be deemed to indirectly  beneficially  own, as described more
     fully in Items 4 and 5 below.


                                                                    Page 4 of 16
--------------------------------------------------------------------------------
(1)   Name of Reporting Persons:
      S.S. or I.R.S. Identification Nos. of above persons (entities only):
      Jan Leschly
--------------------------------------------------------------------------------
(2)   Check the Appropriate Box if a Member of a Group (See Instructions)
      (a)  [x]
      (b)  [ ]

--------------------------------------------------------------------------------
(3)   SEC Use Only:

--------------------------------------------------------------------------------
(4)   Source of Funds (See Instructions):
      AF
--------------------------------------------------------------------------------
(5)   Check Box if Disclosure of Legal Proceedings is Required Pursuant to Items
      2(d) or 2(e): [ ]

--------------------------------------------------------------------------------
(6)   Citizenship or Place of Organization:
      Delaware
--------------------------------------------------------------------------------
NUMBER OF SHARES                    (7)   Sole Voting Power
BENEFICIALLY OWNED                        0
BY EACH REPORTING                  ---------------------------------------------
PERSON WITH                         (8)   Shared Voting Power
                                          14,705,882
                                   ---------------------------------------------
                                    (9)   Sole Dispositive Power
                                          0
                                   ---------------------------------------------
                                   (10)   Shared Dispositive Power
                                          14,705,882
                                   ---------------------------------------------

(11)  Aggregate Amount Beneficially Owned by Each Reporting Person:
      14,705,882
--------------------------------------------------------------------------------
(12)  Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares
      (See Instructions):     1
                           [x]
--------------------------------------------------------------------------------
(13)  Percent of Class Represented by Amount in Row (11):
      41.1%
--------------------------------------------------------------------------------
(14)  Type of Reporting Person (See Instructions):
      IN
--------------------------------------------------------------------------------

1    The Reporting Person disclaims ownership of 65,957,490 additional Shares,
     which it may be deemed to indirectly  beneficially  own, as described more
     fully in Items 4 and 5 below.


                                                                    Page 5 of 16
--------------------------------------------------------------------------------
(1)   Name of Reporting Persons:
      S.S. or I.R.S. Identification Nos. of above persons (entities only):
      David R. Ramsay
--------------------------------------------------------------------------------
(2)   Check the Appropriate Box if a Member of a Group (See Instructions)
      (a)  [x]
      (b)  [ ]

--------------------------------------------------------------------------------
(3)   SEC Use Only:

--------------------------------------------------------------------------------
(4)   Source of Funds (See Instructions):
      AF
--------------------------------------------------------------------------------
(5)   Check Box if Disclosure of Legal Proceedings is Required Pursuant to Items
      2(d) or 2(e): [ ]

--------------------------------------------------------------------------------
(6)   Citizenship or Place of Organization:
      United States
--------------------------------------------------------------------------------
NUMBER OF SHARES                    (7)   Sole Voting Power
BENEFICIALLY OWNED                        0
BY EACH REPORTING                  ---------------------------------------------
PERSON WITH                         (8)   Shared Voting Power
                                          14,705,882
                                   ---------------------------------------------
                                    (9)   Sole Dispositive Power
                                          0
                                   ---------------------------------------------
                                   (10)   Shared Dispositive Power
                                          14,705,882
                                   ---------------------------------------------

(11)  Aggregate Amount Beneficially Owned by Each Reporting Person:
      14,705,882
--------------------------------------------------------------------------------
(12)  Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares
      (See Instructions):     1
                           [x]
--------------------------------------------------------------------------------
(13)  Percent of Class Represented by Amount in Row (11):
      41.1%
--------------------------------------------------------------------------------
(14)  Type of Reporting Person (See Instructions):
      IN
--------------------------------------------------------------------------------

1    The Reporting Person disclaims ownership of 65,957,490 additional Shares,
     which it may be deemed to indirectly  beneficially  own, as described more
     fully in Items 4 and 5 below.



                                                                    Page 6 of 16
--------------------------------------------------------------------------------
(1)   Name of Reporting Persons:
      S.S. or I.R.S. Identification Nos. of above persons (entities only):
      Jerry N. Karabelas
--------------------------------------------------------------------------------
(2)   Check the Appropriate Box if a Member of a Group (See Instructions)
      (a)  [x]
      (b)  [ ]

--------------------------------------------------------------------------------
(3)   SEC Use Only:

--------------------------------------------------------------------------------
(4)   Source of Funds (See Instructions):
      AF
--------------------------------------------------------------------------------
(5)   Check Box if Disclosure of Legal Proceedings is Required Pursuant to Items
      2(d) or 2(e): [ ]

--------------------------------------------------------------------------------
(6)   Citizenship or Place of Organization:
      United States
--------------------------------------------------------------------------------
NUMBER OF SHARES                    (7)   Sole Voting Power
BENEFICIALLY OWNED                        0
BY EACH REPORTING                  ---------------------------------------------
PERSON WITH                         (8)   Shared Voting Power
                                          14,705,882
                                   ---------------------------------------------
                                    (9)   Sole Dispositive Power
                                          0
                                   ---------------------------------------------
                                   (10)   Shared Dispositive Power
                                          14,705,882
                                   ---------------------------------------------

(11)  Aggregate Amount Beneficially Owned by Each Reporting Person:
      14,705,882
--------------------------------------------------------------------------------
(12)  Check Box if the Aggregate Amount in Row (11) Excludes Certain Shares
      (See Instructions):     1
                           [x]
--------------------------------------------------------------------------------
(13)  Percent of Class Represented by Amount in Row (11):
      41.1%
--------------------------------------------------------------------------------
(14)  Type of Reporting Person (See Instructions):
      IN
--------------------------------------------------------------------------------

1    The Reporting Person disclaims ownership of 65,957,490 additional Shares,
     which it may be deemed to indirectly  beneficially  own, as described more
     fully in Items 4 and 5 below.


                                                                    Page 7 of 16

Item 1.       Security and Issuer.

     This statement on Schedule 13D (this  "Schedule 13D") relates to the Common
Stock,  par value $0.01 per share (the Shares") of Halsey Drug Co.,  Inc., a New
York corporation (the "Company"). The principal executive offices of the Company
are located at 695 N. Perryville Road, Crimson Building No. 2, Unit 4, Rockford,
Illinois 61107.

     Item 2. Identity and Background.

     This Schedule 13D is being filed jointly on behalf of the following persons
(the "Filing  Persons"):  Care Capital  Investments  II, LP, a Delaware  limited
partnership  ("CC LP"),  Care  Capital  II,  LLC, a Delaware  limited  liability
company ("CC LLC"),  Jan Leschly,  a managing member of CC LLC, David Ramsay,  a
managing member of CC LLC, and Jerry Karabelas, a managing member of CC LLC. The
Joint Filing Agreement among the Filing Persons is annexed hereto as Exhibit 1.

     The address of the principal  business and office of CC LP and CC LLC is 47
Hulfish Street, Suite 310, Princeton,  NJ 08542. The principal business of CC LP
is to invest in securities.  The principal business of CC LLC is to serve as the
general partner of CC LP.

     Attached as Schedule 1, which is incorporated  herein by reference,  is the
name,  business  address,  present  principal  occupation or  employment,  name,
principal  business and address of the  organization in which such employment is
conducted, and citizenship of each of the managing members of CC LLC.

     During the five years prior to the date hereof,  none of the Filing Persons
or, to the best knowledge of the Filing  Persons,  any managing member of CC LLC
has been convicted in a criminal  proceeding  (excluding  traffic violations and
similar misdemeanors).

     During the five years prior to the date hereof,  none of the Filing Persons
or, to the best knowledge of the Filing  Persons,  any managing member of CC LLC
was a party  to a civil  proceeding  of a  judicial  or  administrative  body of
competent  jurisdiction  as a result of which such person was or is subject to a
judgment,  decree or final order enjoining future  violations of, or prohibiting
or mandating  activities subject to, Federal or State securities laws or finding
any violation with respect to such laws.

     Pursuant to certain  provisions  described  more fully in Item 4 below,  CC
LLC,  CC LP,  Mr.  Leschly,  Mr.  Ramsay and Mr.  Karabelas  may be deemed to be
members of a group along with the other 2002 Holders,  Galen (as defined below),
Oracle (as defined  below),  Michael  Reicher,  Chief  Executive  Officer of the
Company, and Peter Clemens,  Chief Financial Officer of the Company and thus may
be  deemed  to  indirectly   beneficially  own  65,957,490   additional   Shares
beneficially owned by the other 2002 Holders, Galen, Oracle, Mr. Reicher and Mr.
Clemens.  Each of CC LLC,  CC LP, Mr.  Leschly,  Mr.  Ramsay  and Mr.  Karabelas
disclaims ownership of such additional Shares.



                                                                    Page 8 of 16
--------------------------------------------------------------------------------

     Item 3. Source and Amount of Funds or Other Consideration.


     The general and limited  partners of CC LP  contributed,  in the aggregate,
$5,000,000 to CC LP to fund CC LP and the acquisition of a 5% convertible senior
secured debenture of the Company in the principal amount of $5,000,000.

     Item 4. Purpose of Transaction.

     Pursuant to the Debenture Purchase  Agreement,  dated December 20, 2002, by
and  among  the  Company,  CC LP and the other  parties  set forth on  Exhibit A
attached thereto (the "Debenture Purchase Agreement"), annexed hereto as Exhibit
2 and described more fully below, the Company completed a private sale of its 5%
convertible  senior secured  debentures (the  "Debentures") to CC LP and certain
other  purchasers  (collectively,  together  with CC LP,  the  "2002  Holders").
Pursuant to the terms and conditions of the Debenture Purchase Agreement,  CC LP
acquired  a  Debenture  in  the  principal  amount  of  $5,000,000  (the  "CC LP
Debenture")  for  a  purchase  price  of  $5,000,000.  The  CC LP  Debenture  is
convertible  into  Shares at any time at the option of the  holder.  The current
conversion price of the Debentures is $0.34 per share. Thus, CC LP may currently
be deemed to beneficially own 14,705,882 Shares.

     The CC LP Debenture and the Shares  underlying the CC LP Debenture that may
be  acquired by CC LP upon  conversion  thereof and which CC LP may be deemed to
beneficially own were acquired for, and are being held for, investment purposes,
and were acquired in the ordinary  course of business and not for the purpose of
acquiring control of the Company.

     A. Debenture Purchase Agreement

     i. Preemptive Rights

     The Debenture  Purchase  Agreement  provides that if the Company desires to
sell any equity  securities  (including  convertible debt securities) to a third
party,  the Company must first offer to sell such securities to the 2002 Holders
on a pro rata basis on the terms and  conditions  specified  by the Company (the
"Offer").  The Offer must  remain  open for at least 30 days,  and is subject to
certain  limitations  and  exceptions,  as more fully described in the Debenture
Purchase Agreement.

     ii. Co-Sale Rights

     The Debenture  Purchase  Agreement  provides that if Galen Partners,  L.P.,
Galen  Partners   International   III,  L.P.,  Galen  Employee  Fund  III,  L.P.
(collectively,  "Galen"),  Oracle Strategic  Partners L.P.  ("Oracle"),  Michael
Reicher,  Chief  Executive  Officer  of the  Company,  or Peter  Clemens,  Chief
Financial Officer of the Company, intends to transfer any Shares owned by it/him
or any  Debentures  or certain  other  debt  securities  owned by  it/him,  such
transferor  (the  "Selling  Security  Holder")  must notify the 2002  Holders in
writing of such proposed transfer and the terms and conditions  thereof.  Within
15 business  days of the date of such  notice,  each 2002 Holder must notify the
Selling  Security  Holder if such holder elects to  participate  in the proposed
transfer  described  in the written  notice  provided  by the  Selling  Security
Holder.  Any 2002 Holder that desires to  participate in such transfer may do so
on a pro rata  basis,  subject to certain  terms and  conditions,  as more fully
described in the Debenture Purchase Agreement.



                                                              Page 9 of 16 pages
--------------------------------------------------------------------------------

     iii. Amendments to Company's Certificate of Incorporation and Voting Rights

     The Debenture  Purchase Agreement provides that the Company will present to
its shareholders and  debentureholders  for  consideration at the Company's next
annual  meeting  of  shareholders:   (a)  a  proposal  to  amend  the  Company's
Certificate  of  Incorporation  to  increase  the  number of  authorized  Shares
available for issuance  from  80,000,000 to such number of Shares as shall equal
the sum of (I) the Company's issued and outstanding Shares, plus (II) the number
of Shares issuable upon the conversion and exercise of the Company's outstanding
convertible securities, plus (III) the number of Shares issuable upon conversion
of the  Debentures  and the exercise of certain  warrants,  plus (IV) 50 million
shares,  as such sum shall be  rounded  up to the  nearest  whole  five  million
Shares;  (b) a proposal to amend the Company's  Certificate of  Incorporation to
provide that holders of the Debentures shall have the right to vote as part of a
single  class  with all  holders  of  Shares  on all  matters  to be voted on by
shareholders,  with the  holders of  Debentures  having  such number of votes as
shall  equal the number of votes  they would have had had such  debentureholders
converted  the entire  outstanding  principal  amount of their  Debentures  into
Shares  immediately  prior to the record date  relating to such vote,  provided,
that any  Debentures  held by CC LP shall  have no such  voting  rights  and the
Certificate of  Incorporation  shall state the same; and (c) a proposal to elect
as directors one designee of each of CC LP and Essex  Woodlands  Health Ventures
Fund V ("Essex"),  which designees  shall also be appointed,  if so requested by
such designee in its sole discretion,  to the Company's  Executive Committee and
Compensation Committee and any other committee of the Company.

     iv. Appointment of CC LP Designee

     Pursuant to the terms and conditions of the Debenture  Purchase  Agreement,
as of December 20, 2002, the Board of Directors of the Company was reconstituted
to include one  director-designee of CC LP, Mr. Karabelas.  Mr. Karabelas filled
an existing vacancy on the Company's Board of Directors.

     The above summary  description of the Debenture  Purchase  Agreement is not
intended to be complete  and is  qualified  in its  entirety by reference to the
full text of the Debenture Purchase Agreement annexed hereto as Exhibit 2, which
is incorporated herein by reference.

     B. The CC LP Debenture

     The CC LP  Debenture,  annexed  hereto as Exhibit 4, bears  interest at the
rate of 5% per annum. Such interest payments are to be made (i) 50% in cash, and
(ii)  50%  in  kind  (i.e.,  in the  form  of  additional  Debentures  that  are
substantially  identical  to the CC LP  Debenture),  subject  to the  terms  and
conditions  set forth in the CC LP  Debenture.  The  maturity  date of the CC LP
Debenture is March 31, 2006. The CC LP Debenture is  convertible  into Shares at
any time at the  option of CC LP.  The  conversion  price is  subject to certain
downward adjustments,  as set forth more fully in the CC LP Debenture. The above
summary description of the CC LP Debenture is not intended to be complete and is
qualified in its entirety by reference to the full text of the CC LP  Debenture,
which is incorporated herein by reference.



                                                             Page 10 of 16 pages
--------------------------------------------------------------------------------

     C. The Debentureholders Agreement

     CC LP is a party to the  Debentureholders  Agreement,  dated as of December
20, 2002, by and among the Company,  the 2002 Holders and the holders of certain
other Company debentures (the "Debentureholders  Agreement"),  annexed hereto as
Exhibit 5. The Debentureholders Agreement provides the 2002 Holders with certain
veto rights with respect to any modification of the rights of the holders of the
Debentures,  the  issuance  of any senior  securities  by the  Company,  certain
distributions to Company security  holders and certain  extraordinary  corporate
transactions   by  the  Company   (including,   without   limitation,   mergers,
liquidations,  certain joint ventures,  etc.). Any such transaction requires the
affirmative  prior  written  consent  of at  least  66 2/3%  of the  outstanding
principal  amount  of  the  Debentures  then  outstanding.   The  above  summary
description of the Debentureholders Agreement is not intended to be complete and
is   qualified   in  its   entirety  by  reference  to  the  full  text  of  the
Debentureholders Agreement, which is incorporated herein by reference.

     D. Registration Rights Agreement

     CC LP, the other 2002 Holders and the other parties  signatory  thereto are
party to the  Registration  Rights  Agreement,  dated as of December  20,  2002,
annexed  hereto as Exhibit 6, that provides that, in certain  circumstances  and
upon the terms and  conditions  stated  therein,  the 2002 Holders will have the
right to request the Company to effect a registration (a "Registration Request")
of the Debentures and the Shares underlying the Debentures.  In addition, in the
event that the Company  proposes to register any of its  securities  for its own
account  (other than certain  registrations  relating to a stock option or other
similar employee benefit plan or relating to certain business combinations),  CC
LP will have the right,  subject to a priority in favor of the Company,  to have
the Shares  issuable  upon  conversion  of the CC LP Debenture  included in such
registration  on a pro rata basis with other holders of  registrable  securities
being included in such registration.

     The above summary  description of the Registration  Rights Agreement is not
intended to be complete  and is  qualified  in its  entirety by reference to the
full text of the Registration Rights Agreement,  which is incorporated herein by
reference.

     E. Reserved Shares Waiver Agreement

     CC LP is  party  to the  Reserved  Shares  Waiver  Agreement,  dated  as of
December 20, 2002, by and among the Company, Galen, Oracle, CC LP, Essex, Watson
Pharmaceuticals,  Inc.  ("Watson") and the other parties  signatory thereto (the
"Reserved Shares Waiver"), annexed hereto as Exhibit 7. Pursuant to the Reserved
Shares Waiver,  each of Galen and Oracle  (collectively,  the "Waiving Parties")
agreed to release in favor of CC LP,  Essex and  Watson  their  rights to Shares
previously  reserved by the Company for issuance to the Waiving Parties upon the
conversion  into Shares of convertible  securities  held by the Waiving  Parties
(collectively,  the "Reserved Shares").  Pursuant to the Reserved Shares Waiver,
the  Reserved  Shares were  reallocated  to and  reserved for issuance to CC LP,
Essex and  Watson on a pro rata  basis.  The above  summary  description  of the
Reserved  Shares  Waiver is not  intended to be complete and is qualified in its
entirety by reference to the full text of the Reserved  Shares Waiver,  which is
incorporated herein by reference.



                                                             Page 11 of 16 pages
--------------------------------------------------------------------------------

     F. Voting Agreement

     In  connection   with  the  proposed   amendments  to  the  Certificate  of
Incorporation  of the Company and the election of directors of the Company,  the
Company,  CC LP and certain other security holders executed a Voting  Agreement,
dated December 20, 2002 (the "Voting  Agreement"),  annexed hereto as Exhibit 3,
providing  that,  among other  things,  each such  person  shall vote the Shares
(including Shares underlying any existing debentures of the Company) owned by it
in favor of the  proposals  described  above  in Item 4, A.  Debenture  Purchase
Agreement,  iii. Amendments to Company's Certificate of Incorporation and Voting
Rights,  above.  The Voting Agreement also provides that each of the signatories
to the Voting Agreement shall vote the Shares  (including  Shares underlying any
existing  debentures of the  Company),  and take or cause to be taken such other
actions, as may be required from time to time to elect to the Board of Directors
of the Company one person designated by CC LP.

     The above summary description of the Voting Agreement is not intended to be
complete  and is  qualified in its entirety by reference to the full text of the
Voting  Agreement  annexed hereto as Exhibit 3, which is incorporated  herein by
reference.

     Except as set forth herein, or as set forth in the Exhibits annexed hereto,
none of the Filing  Persons has any plans or  proposals  that relate to or would
result in any of the following:

     (i) the acquisition by any person of additional  securities of the Company,
or the disposition of securities of the Company;

     (ii)  an   extraordinary   corporate   transaction,   such  as  a   merger,
reorganization or liquidation, involving the Company or any of its subsidiaries;

     (iii) a sale or transfer  of a material  amount of assets of the Company or
of any of its subsidiaries;

     (iv) any change in the present  board of  directors  or  management  of the
Company,  including plans or proposals to change the number or term of directors
or to fill any existing vacancies on the board;

     (v) any material change in the present capitalization or dividend policy of
the Company;

     (vi) any other  material  change in the  Company's  business  or  corporate
structure,  including  but  not  limited  to,  if the  Company  is a  registered
closed-end investment company, any plans or proposals to make any changes in its
investment  policy for which a vote is required by Section 13 of the  Investment
Company Act of 1940;

     (vii) changes in the Company's charter, bylaws or instruments corresponding
thereto or other  actions  which may impede  the  acquisition  of control of the
Company by any person;



                                                             Page 12 of 16 pages
--------------------------------------------------------------------------------

     (viii)  causing a class of  securities of the Company to be delisted from a
national  securities  exchange or to cease to be  authorized  to be quoted in an
inter-dealer quotation system of a registered national securities association;

     (ix) a class of equity  securities  of the Company  becoming  eligible  for
termination of registration pursuant to Section 12(g)(4) of the Act; or

     (x) any action similar to any of those enumerated above. The Filing Persons
may in the  future  directly  acquire  or  dispose  of Shares in open  market or
private  transactions,  block  purchases or  otherwise.  The Filing  Persons may
continue  to hold or dispose of all or some of the  securities  reported  herein
from time to time,  in each case in open market or private  transactions,  block
sales or purchases or otherwise,  subject to compliance  with applicable law. In
that  regard,  pursuant  to  the  Registration  Rights  Agreement,  CC LP may be
entitled to certain registration rights with respect to the Shares to permit the
public sale thereof in accordance  with the  Securities Act of 1933, as amended,
and applicable  state  securities  laws.  Each of the Filing Persons may, at any
time and  from  time to time,  review  or  reconsider  his or its  position  and
formulate plans or proposals with respect thereto,  but has no present intention
of doing so.

     Item 5. Interest in Securities of the Issuer.

     (a) As more fully  described  in Item 4 above,  because of the  convertible
feature  of the  Debentures,  the  Debenture  Purchase  Agreement  and the other
documents  entered into by CC LP with respect to the  transaction,  CC LP may be
deemed to be the beneficial  owner of  approximately  14,705,882  Shares,  which
constitutes approximately 41.1% of the outstanding capital stock of the Company.
By virtue of CC LLC's  status as general  partner of CC LP, CC LLC may be deemed
to be the indirect  beneficial owner of the 14,705,882  Shares that CC LP may be
deemed  to  beneficially  own,  which  constitutes  approximately  41.1%  of the
outstanding capital stock of the Company. Messrs. Leschly, Karabelas and Ramsay,
as  managing  members of CC LLC,  may be deemed to be the  beneficial  owners of
14,705,882  Shares,  which  constitutes  approximately  41.1% of the outstanding
capital stock of the Company.  As more fully  described in Item 4 above, CC LLC,
CC LP,  Mr.  Leschly,  Mr.  Ramsay  and Mr.  Karabelas  may be  deemed to be the
indirect beneficial owner of 65,957,490  additional Shares beneficially owned by
the other 2002  Holders,  Galen,  Oracle,  Mr.  Reicher and Mr.  Clemens,  which
additional Shares together with the 14,705,882 Shares constitutes  approximately
79.3% of the  outstanding  capital stock of the Company.  Each of CC LLC, CC LP,
Mr. Leschly, Mr. Ramsay and Mr. Karabelas disclaims ownership of such additional
Shares.  Ownership  interests set forth herein are based on the number of shares
of capital stock of the Company  outstanding as of December 20, 2002 provided to
the Filing Persons by the Company.

     (b) By virtue  of its  status as  general  partner  of CC LP, CC LLC may be
deemed to have shared  voting and  dispositive  power with respect to the Shares
that CC LP may be  deemed to  beneficially  own.  By  virtue of their  status as
managing members of CC LLC, each of Messrs. Leschly, Karabelas and Ramsay may be
deemed to have shared voting and dispositive  power with respect to such Shares.
Each of Messrs. Leschly, Karabelas and Ramsay hereby disclaim such ownership.



                                                             Page 13 of 16 pages

--------------------------------------------------------------------------------
     (c) During the past sixty days prior to the date hereof, none of the Filing
Persons or, to the  knowledge  of the Filing  Persons,  any  executive  officer,
director  or  managing  member of any of the Filing  Persons  has engaged in any
transaction in the Shares.

     (d) No person, other than the Filing Persons, is known to have the right to
receive or the power to direct the receipt of  dividends  from,  or the proceeds
from the sale of, any Shares owned by the Filing Persons.

     (e) Not applicable.

     Item 6.  Contracts,  Arrangements,  Understandings  or  Relationships  with
Respect to Securities of the Issuer.

     See response to Item 4.

     A copy of the Debenture  Purchase Agreement is attached hereto as Exhibit 2
and is incorporated herein by reference.

     A copy of the  Voting  Agreement  is  attached  hereto as  Exhibit 3 and is
incorporated herein by reference.

     A copy of the CC LP  Debenture  is  attached  hereto  as  Exhibit  4 and is
incorporated herein by reference.

     A copy of the  Debentureholders  Agreement is attached  hereto as Exhibit 5
and is incorporated herein by reference.

     A copy of the Registration Rights Agreement is attached hereto as Exhibit 6
and is incorporated herein by

reference.

     A copy of the Reserved Shares Waiver is attached hereto as Exhibit 7 and is
incorporated herein by reference.

     Except for the agreements and instruments described in the response to Item
4,  to the  best  knowledge  of the  Filing  Persons,  there  are no  contracts,
arrangements,  understandings  or  relationships  (legal or otherwise) among the
persons  named in Item 2 and between such persons and any person with respect to
any securities of the Company, including, but not limited to, transfer or voting
of any of  the  securities,  finder's  fees,  joint  ventures,  loan  or  option
arrangements, puts or calls, guarantees of profits, division of profits or loss,
or the giving or withholding of proxies.



                                                             Page 14 of 16 pages
--------------------------------------------------------------------------------

     Item 7. Material to be Filed as Exhibits.

     Exhibit 1         Joint Filing  Agreement dated as of December 30, 2002,
                       among the Filing Persons.

     Exhibit 2         Debenture Purchase  Agreement,  dated as of December
                       20, 2002, by and among the Company, Care Capital
                       Investments II, LP and the other parties set forth on
                       Exhibit A attached thereto.

     Exhibit 3         Voting Agreement, dated as of December 20, 2002, by and
                       among the Company, Care Capital Investments II, LP and
                       the other parties set forth on the signature pages
                       attached thereto.

     Exhibit 4         5% Convertible Senior Secured Debenture due March 31,
                       2006, dated December 20, 2002, executed by the Company
                       in favor of Care Capital Investments II, LP.

     Exhibit 5         Debentureholders Agreement, dated as of December 20,
                       2002, by and among the Company, Care Capital Investments
                       II, LP and the other parties set forth on the signature
                       pages attached thereto.

     Exhibit 6         Registration Rights Agreement, dated as of December 20,
                       2002, by and among the Company, Care Capital Investments
                       II, LP and the other parties set forth on Schedule 1
                       attached thereto.

     Exhibit 7         Reserved Shares Waiver Agreement, dated as of December
                       20, 2002, by and among the Company, Care Capital
                       Investments II, LP and the other parties set forth on the
                       signature pages attached thereto.

     Exhibit 8         Power of Attorney of Jan Leschly and Jerry N. Karabelas,
                       dated December 30, 2002.




                                                             Page 15 of 16 pages
--------------------------------------------------------------------------------


                                    SIGNATURE

     After  reasonable  inquiry  and to the best  knowledge  and  belief  of the
undersigned,  the  undersigned  certify that the  information  set forth in this
statement is true, complete and correct.

Dated:  December 30, 2002       CARE CAPITAL INVESTMENTS II, LP
                                By: Care Capital II, LLC, as General Partner


                                By: /s/ David R. Ramsay
                                    --------------------------------------------
                                    Name:  David R. Ramsay
                                    Title: Attorney-in-Fact


Dated:  December 30, 2002

                                  Care Capital II, LLC


                                  By: /s/ David R. Ramsay
                                      ------------------------------------------
                                      Name:   David R. Ramsay
                                      Title:  Attorney-in-Fact


Dated:  December 30, 2002        /s/ David R. Ramsay
                                 -----------------------------------------------
                                 David R. Ramsay, as attorney-in-fact
                                 for Jan Leschly



Dated:  December 30, 2002       /s/ David R. Ramsay
                                ------------------------------------------------
                                David R. Ramsay



Dated:  December 30, 2002      /s/ David R. Ramsay
                               -------------------------------------------------
                               David R. Ramsay, as attorney-in-fact
                               for Jerry N. Karabelas





                                                             Page 16 of 16 pages
--------------------------------------------------------------------------------
                                                                      Schedule 1

                    Managing Members of Care Capital II, LLC

     The  following  table  sets  forth  the  name,  business  address,  present
principal occupation or employment,  the name, principal business and address of
the organization in which such employment is conducted,  and citizenship of each
of the managing members of Care Capital II, LLC:



                         

------------------------------------------------------------------------------------------------------------------------------------
           NAME                    ADDRESS                         CITIZENSHIP                PRINCIPAL OCCUPATION
------------------------------------------------------------------------------------------------------------------------------------
------------------------------------------------------------------------------------------------------------------------------------
Jan Leschly                  c/o Care Capital, LLC, 47              Denmark                  Managing Member, Care Capital II, LLC
                             Hulfish Street, Suite 310,
                             Princeton, NJ 08542
------------------------------------------------------------------------------------------------------------------------------------
------------------------------------------------------------------------------------------------------------------------------------
Jerry N. Karabelas           c/o Care Capital, LLC, 47              United States            Managing Member, Care Capital II, LLC
                             Hulfish Street, Suite 310,
                             Princeton, NJ 08542

------------------------------------------------------------------------------------------------------------------------------------
------------------------------------------------------------------------------------------------------------------------------------
David R. Ramsay              c/o Care Capital, LLC, 47             United States            Managing Member, Care Capital II, LLC
                             Hulfish Street, Suite 310,
                             Princeton, NJ 08542
------------------------------------------------------------------------------------------------------------------------------------