UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   ___________

                                    FORM 8-K

                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934



Date of Report (Date of earliest event reported)            April 1, 2006
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                           ENZON PHARMACEUTICALS, INC.
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             (Exact name of registrant as specified in its charter)



 Delaware                        0-12957                        22-2372868
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(State or other jurisdiction   (Commission File No.)  (IRS Identification No.)
of incorporation)


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                685 Route 202/206, Bridgewater, New Jersey 08807
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               (Address of principal executive offices) (Zip Code)



Registrant's telephone number, including area code          (908) 541-8600
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         (Former name or former address, if changed since last report)
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Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions:

[ ] Written communication  pursuant to Rule 425 under the Securities Act (17 CFR
230.425)

[ ] Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17 CFR
240.14a-12)

[ ] Pre-commencement  communication pursuant to Rule 14d-2(b) under the Exchange
Act (17 CFR 240.14d-2(b)

[ ] Pre-commencement  communication pursuant to Rule 13e-4(c) under the Exchange
Act (17 CFR 240.13e-4(c))




Item 1.01 Entry into a Material Definitive Agreement.

On April 1, 2006, the Compensation  Committee of the Board of Directors of Enzon
Pharmaceuticals,  Inc.  ("Enzon")  approved an increase in the  compensation  of
certain  executive  officers  of Enzon.  In  November  2005,  at the time of the
determination  of  executive  officer  annual  bonuses  for 2005 and the regular
annual  increase in executive  officer base salaries for 2006, the  Compensation
Committee determined that the advice of an outside compensation  consulting firm
was  necessary  to  assist  the   Compensation   Committee  in  determining  the
appropriate  compensation  for the  Company's  executive  officers for 2006.  In
February 2006, the Compensation  Committee  engaged an independent  compensation
consulting   firm  to  prepare  a  benchmarking   study  of  executive   officer
compensation.  After  taking  into  account  the results of this study and other
relevant information, the Compensation Committee determined to increase the base
salary of, and provide  incentive  compensation to, certain of Enzon's executive
officers as set forth below.

                         

-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
  Name and Title of Executive      Base Salary      Target 2006 Cash    2006 Cash Bonus    Restricted      Stock
            Officer                 effective            Bonus               Range            Stock       Options
                                  April 1, 2006    (as percentage of   (as percentage of   Units Grant     Grant
                                                      base salary)        base salary)
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
Jeffrey Buchalter,                       $700,000  100%                0-200%              198,100      367,900
President and Chief Executive
Officer
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
Ivan Horak, Executive Vice               $475,000  60%                 0-120%              66,200       122,900
President, Research and
Development and Chief
Scientific Officer
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
Craig Tooman, Executive Vice             $400,000  60%                 0-120%              55,800       103,500
President, Finance and Chief
Financial Officer
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
Ralph del Campo, Executive               $367,500  50%                 0-100%              42,000       78,000
Vice President, Operations
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------
Paul Davit, Executive Vice               $325,000  50%                 0-100%              31,900       59,200
President, Human Resources
-------------------------------- ----------------- ------------------- ------------------- ------------ -------------


The restricted  stock units and options to purchase common stock were granted on
April 3, 2006.  The 2006 annual cash bonuses for the executive  officers will be
based on objective individual and corporate objectives,  targets and factors and
evaluation as to the extent of achievement thereof.  The individual  objectives,
targets and factors were  separately  determined for each executive  officer and
reflect operational and other achievements  specific to such executive officer's
position and duties.




                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

Dated:  April 5, 2006

                                 By:  /s/ CRAIG A. TOOMAN
                                 Name:  Craig A. Tooman
                                 Title:  Executive Vice President, Finance
                                 and Chief Financial Officer