UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    Form 13F
                               Form 13F COVER PAGE
Report for the Calendar Year or Quarter Ended: 12/31/2010
Check here if Amendment []; Amendment Number:
                                               -------
This Amendment (Check only one.):               [] is a restatement.
                                                [] adds new holdings entries.

Institutional Investment Manager Filing this Report:


Name:      Burke & Herbert Bank & Trust Co.

Address:   PO Box 268 Alexandria


Form 13F File Number: 028-05313


The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.

Persons Signing this Report on Behalf of Reporting Manager:

Name:   M. Patricia Barron
Title:  Vice President
Phone:  703-549-6600

Signature,  Place,  and  Date  of  Signing:

/s/ M. Patricia Barron             Alexandria, VA                     1/4/2011
---------------------------------  ---------------------------------  ----------
[Signature]                        [City, State]                      [Date]



Report  Type  (Check  only  one):

[X]     13F HOLDINGS REPORT. (Check here if all holdings of this reporting
        manager are reported in this report.)

[ ]     13F NOTICE. (Check here if no holdings reported are in this report,
        and all holdings are reported by other reporting manager(s).)

[ ]     13F COMBINATION REPORT. (Check here if a portion of the holdings for
        this reporting manager are reported in this report and a portion are
        reported by other reporting manager(s).)

List of Other Managers Reporting for this Manager:




                              Form 13F SUMMARY PAGE

Report Summary:

Number of Other Included Managers:                    0

Form 13F Information Table Entry Total:             154

Form 13F Information Table Value Total:  $       86,464
                                         --------------
                                         (In Thousands)


List of Other Included Managers:

Provide a numbered list of the name(s) and 13F file number(s) of all
institutional investment managers with respect to which this report is filed,
other than the manager filing this report.
NONE







                                                  FORM 13F INFORMATION TABLE

          COLUMN 1              COLUMN 2    COLUMN 3  COLUMN 4     COLUMN 5       COLUMN 6  COLUMN 7      COLUMN 8
---------------------------- -------------- --------- -------- ----------------- ---------- -------- -------------------
                                                       VALUE   SHRS OR  SH/ PUT/ INVESTMENT  OTHER    VOTING AUTHORITY
       NAME OF ISSUER        TITLE OF CLASS   CUSIP   (x$1000) PRN AMT  PRN CALL DISCRETION MANAGERS  SOLE   SHARED NONE
---------------------------- -------------- --------- -------- -------- --- ---- ---------- -------- ------- ------ ----
                                                                                   
AT&T INC                     COM            00206R102      829   28,229 SH       SOLE                 28,229      0    0
AT&T INC                     COM            00206R102      810   27,561 SH       DEFINED              27,561      0    0
ABBOTT LABS                  COM            002824100      556   11,600 SH       SOLE                 11,600      0    0
ABBOTT LABS                  COM            002824100      492   10,260 SH       DEFINED              10,260      0    0
ALTRIA GROUP INC             COM            02209S103      476   19,350 SH       SOLE                 19,350      0    0
ALTRIA GROUP INC             COM            02209S103      155    6,300 SH       DEFINED               6,300      0    0
AMERICAN EXPRESS CO          COM            025816109      220    5,116 SH       SOLE                  5,116      0    0
AMERICAN EXPRESS CO          COM            025816109       58    1,350 SH       DEFINED               1,350      0    0
APPLE INC                    COM            037833100      273      845 SH       SOLE                    845      0    0
APPLE INC                    COM            037833100      573    1,775 SH       DEFINED               1,775      0    0
ATLAS PIPELINE PARTNERS LP   UNIT L P INT   049392103      244    9,900 SH       DEFINED               9,900      0    0
BP PLC                       SPONSORED ADR  055622104      637   14,432 SH       SOLE                 14,432      0    0
BP PLC                       SPONSORED ADR  055622104       74    1,666 SH       DEFINED               1,666      0    0
BANCO BILBAO VIZCAYA ARGENTA SPONSORED ADR  05946K101      143   14,045 SH       SOLE                 14,045      0    0
BANK OF AMERICA CORPORATION  COM            060505104      117    8,760 SH       SOLE                  8,760      0    0
BANK OF AMERICA CORPORATION  COM            060505104      406   30,402 SH       DEFINED              30,402      0    0
BANK OF NEW YORK MELLON CORP COM            064058100        5      150 SH       SOLE                    150      0    0
BANK OF NEW YORK MELLON CORP COM            064058100      563   18,639 SH       DEFINED              18,639      0    0
BAXTER INTL INC              COM            071813109      154    3,050 SH       SOLE                  3,050      0    0
BAXTER INTL INC              COM            071813109       48      950 SH       DEFINED                 950      0    0
BERKSHIRE HATHAWAY INC DEL   CL A           084670108      361        3 SH       SOLE                      3      0    0
BERKSHIRE HATHAWAY INC DEL   CL A           084670108      241        2 SH       DEFINED                   2      0    0
BERKSHIRE HATHAWAY INC DEL   CL B NEW       084670702       85    1,055 SH       SOLE                  1,055      0    0
BERKSHIRE HATHAWAY INC DEL   CL B NEW       084670702      209    2,607 SH       DEFINED               2,607      0    0
BLACKROCK INC                COM            09247X101      114      600 SH       SOLE                    600      0    0
BLACKROCK INC                COM            09247X101      124      650 SH       DEFINED                 650      0    0
BOEING CO                    COM            097023105      183    2,802 SH       SOLE                  2,802      0    0
BOEING CO                    COM            097023105       33      500 SH       DEFINED                 500      0    0
BRISTOL MYERS SQUIBB CO      COM            110122108      250    9,446 SH       SOLE                  9,446      0    0
BRISTOL MYERS SQUIBB CO      COM            110122108      159    6,020 SH       DEFINED               6,020      0    0
BUCKEYE PARTNERS L P         UNIT LTD PARTN 118230101      207    3,100 SH       DEFINED               3,100      0    0
BURKE&HERBERT B&T ALEXANDRIA COM            121331102   15,047    6,614 SH       SOLE                  6,614      0    0
BURKE&HERBERT B&T ALEXANDRIA COM            121331102    1,863      819 SH       DEFINED                 819      0    0
CIGNA CORP                   COM            125509109      556   15,180 SH       DEFINED              15,180      0    0
CHEVRON CORP NEW             COM            166764100      979   10,724 SH       SOLE                 10,724      0    0
CHEVRON CORP NEW             COM            166764100    2,042   22,379 SH       DEFINED              22,379      0    0
CISCO SYS INC                COM            17275R102      251   12,399 SH       SOLE                 12,399      0    0
CISCO SYS INC                COM            17275R102      158    7,800 SH       DEFINED               7,800      0    0
CITIGROUP INC                COM            172967101       43    9,003 SH       SOLE                  9,003      0    0
CITIGROUP INC                COM            172967101      419   88,495 SH       DEFINED              88,495      0    0
COCA COLA CO                 COM            191216100      741   11,264 SH       SOLE                 11,264      0    0
COCA COLA CO                 COM            191216100      510    7,750 SH       DEFINED               7,750      0    0
COLGATE PALMOLIVE CO         COM            194162103      265    3,295 SH       SOLE                  3,295      0    0
COLGATE PALMOLIVE CO         COM            194162103      157    1,950 SH       DEFINED               1,950      0    0
CONOCOPHILLIPS               COM            20825C104       39      580 SH       SOLE                    580      0    0
CONOCOPHILLIPS               COM            20825C104      223    3,280 SH       DEFINED               3,280      0    0
DELL INC                     COM            24702R101       75    5,500 SH       SOLE                  5,500      0    0
DELL INC                     COM            24702R101       64    4,700 SH       DEFINED               4,700      0    0
DISNEY WALT CO               COM DISNEY     254687106      253    6,742 SH       SOLE                  6,742      0    0
DISNEY WALT CO               COM DISNEY     254687106      191    5,100 SH       DEFINED               5,100      0    0
DOMINION RES INC VA NEW      COM            25746U109      480   11,226 SH       SOLE                 11,226      0    0
DOMINION RES INC VA NEW      COM            25746U109      313    7,324 SH       DEFINED               7,324      0    0
DU PONT E I DE NEMOURS & CO  COM            263534109      642   12,872 SH       SOLE                 12,872      0    0
DU PONT E I DE NEMOURS & CO  COM            263534109      614   12,301 SH       DEFINED              12,301      0    0
DUN & BRADSTREET CORP DEL NE COM            26483E100      205    2,500 SH       DEFINED               2,500      0    0
EMERSON ELEC CO              COM            291011104      169    2,964 SH       SOLE                  2,964      0    0
EMERSON ELEC CO              COM            291011104      106    1,860 SH       DEFINED               1,860      0    0
EXELON CORP                  COM            30161N101      120    2,882 SH       SOLE                  2,882      0    0
EXELON CORP                  COM            30161N101      231    5,550 SH       DEFINED               5,550      0    0
EXXON MOBIL CORP             COM            30231G102    3,076   42,074 SH       SOLE                 42,074      0    0






                                                  FORM 13F INFORMATION TABLE

          COLUMN 1              COLUMN 2    COLUMN 3  COLUMN 4     COLUMN 5       COLUMN 6  COLUMN 7      COLUMN 8
---------------------------- -------------- --------- -------- ----------------- ---------- -------- -------------------
                                                       VALUE   SHRS OR  SH/ PUT/ INVESTMENT  OTHER    VOTING AUTHORITY
       NAME OF ISSUER        TITLE OF CLASS   CUSIP   (x$1000) PRN AMT  PRN CALL DISCRETION MANAGERS  SOLE   SHARED NONE
---------------------------- -------------- --------- -------- -------- --- ---- ---------- -------- ------- ------ ----
                                                                                   
EXXON MOBIL CORP             COM            30231G102    4,749   64,946 SH       DEFINED              64,946      0    0
FEDERAL REALTY INVT TR       SH BEN INT NEW 313747206      713    9,150 SH       DEFINED               9,150      0    0
FLUOR CORP NEW               COM            343412102      417    6,300 SH       DEFINED               6,300      0    0
FORTUNE BRANDS INC           COM            349631101      362    6,000 SH       DEFINED               6,000      0    0
FREEPORT-MCMORAN COPPER & GO COM            35671D857    1,396   11,621 SH       DEFINED              11,621      0    0
FRONTIER COMMUNICATIONS CORP COM            35906A108       46    4,764 SH       SOLE                  4,764      0    0
FRONTIER COMMUNICATIONS CORP COM            35906A108       56    5,763 SH       DEFINED               5,763      0    0
GENERAL ELECTRIC CO          COM            369604103    1,872  102,341 SH       SOLE                102,341      0    0
GENERAL ELECTRIC CO          COM            369604103    2,021  110,523 SH       DEFINED             110,523      0    0
GOOGLE INC                   CL A           38259P508       27       45 SH       SOLE                     45      0    0
GOOGLE INC                   CL A           38259P508      190      320 SH       DEFINED                 320      0    0
HEWLETT PACKARD CO           COM            428236103      859   20,412 SH       SOLE                 20,412      0    0
HEWLETT PACKARD CO           COM            428236103      487   11,575 SH       DEFINED              11,575      0    0
HOME DEPOT INC               COM            437076102      153    4,375 SH       SOLE                  4,375      0    0
HOME DEPOT INC               COM            437076102      189    5,383 SH       DEFINED               5,383      0    0
HONEYWELL INTL INC           COM            438516106      280    5,262 SH       SOLE                  5,262      0    0
HONEYWELL INTL INC           COM            438516106       80    1,500 SH       DEFINED               1,500      0    0
INTEL CORP                   COM            458140100      331   15,728 SH       SOLE                 15,728      0    0
INTEL CORP                   COM            458140100      185    8,775 SH       DEFINED               8,775      0    0
INTERNATIONAL BUSINESS MACHS COM            459200101      736    5,012 SH       SOLE                  5,012      0    0
INTERNATIONAL BUSINESS MACHS COM            459200101      466    3,177 SH       DEFINED               3,177      0    0
ISHARES TR                   BARCLY USAGG B 464287226      250    2,365 SH       SOLE                  2,365      0    0
ISHARES TR                   RUSSELL 3000   464287689      245    3,270 SH       DEFINED               3,270      0    0
ISHARES TR                   DJ US INDEX FD 464287846      209    3,300 SH       SOLE                  3,300      0    0
JPMORGAN CHASE & CO          COM            46625H100      183    4,307 SH       SOLE                  4,307      0    0
JPMORGAN CHASE & CO          COM            46625H100      107    2,520 SH       DEFINED               2,520      0    0
JOHNSON & JOHNSON            COM            478160104    2,824   45,661 SH       SOLE                 45,661      0    0
JOHNSON & JOHNSON            COM            478160104      585    9,460 SH       DEFINED               9,460      0    0
JOHNSON CTLS INC             COM            478366107      256    6,700 SH       DEFINED               6,700      0    0
KIMBERLY CLARK CORP          COM            494368103      261    4,139 SH       SOLE                  4,139      0    0
KIMBERLY CLARK CORP          COM            494368103      183    2,898 SH       DEFINED               2,498    400    0
KRAFT FOODS INC              CL A           50075N104      400   12,703 SH       SOLE                 12,703      0    0
KRAFT FOODS INC              CL A           50075N104       62    1,961 SH       DEFINED               1,961      0    0
LOCKHEED MARTIN CORP         COM            539830109      159    2,280 SH       SOLE                  2,280      0    0
LOCKHEED MARTIN CORP         COM            539830109       42      600 SH       DEFINED                 600      0    0
MANULIFE FINL CORP           COM            56501R106      154    8,988 SH       SOLE                  8,988      0    0
MANULIFE FINL CORP           COM            56501R106      285   16,608 SH       DEFINED              16,608      0    0
MCDONALDS CORP               COM            580135101      261    3,404 SH       SOLE                  3,404      0    0
MCDONALDS CORP               COM            580135101      111    1,450 SH       DEFINED               1,450      0    0
MEDCO HEALTH SOLUTIONS INC   COM            58405U102      283    4,626 SH       SOLE                  4,626      0    0
MEDCO HEALTH SOLUTIONS INC   COM            58405U102       84    1,372 SH       DEFINED               1,372      0    0
MEDTRONIC INC                COM            585055106      268    7,224 SH       SOLE                  7,224      0    0
MEDTRONIC INC                COM            585055106      124    3,350 SH       DEFINED               3,350      0    0
MERCK & CO INC NEW           COM            58933Y105      554   15,380 SH       SOLE                 15,380      0    0
MERCK & CO INC NEW           COM            58933Y105      644   17,880 SH       DEFINED              17,880      0    0
MICROSOFT CORP               COM            594918104      320   11,453 SH       SOLE                 11,453      0    0
MICROSOFT CORP               COM            594918104      539   19,325 SH       DEFINED              19,325      0    0
NATURAL RESOURCE PARTNERS L  COM UNIT L P   63900P103       43    1,300 SH       SOLE                  1,300      0    0
NATURAL RESOURCE PARTNERS L  COM UNIT L P   63900P103      169    5,100 SH       DEFINED               5,100      0    0
NEXTERA ENERGY INC           COM            65339F101      256    4,932 SH       SOLE                  4,932      0    0
NEXTERA ENERGY INC           COM            65339F101      158    3,040 SH       DEFINED               3,040      0    0
NORFOLK SOUTHERN CORP        COM            655844108      737   11,739 SH       SOLE                 11,739      0    0
NORFOLK SOUTHERN CORP        COM            655844108      415    6,600 SH       DEFINED               6,600      0    0
OMNICOM GROUP INC            COM            681919106       33      720 SH       SOLE                    720      0    0
OMNICOM GROUP INC            COM            681919106      183    4,000 SH       DEFINED               4,000      0    0
ORACLE CORP                  COM            68389X105      108    3,450 SH       SOLE                  3,450      0    0
ORACLE CORP                  COM            68389X105      186    5,930 SH       DEFINED               5,930      0    0
PPG INDS INC                 COM            693506107      256    3,050 SH       SOLE                  3,050      0    0
PEPSICO INC                  COM            713448108      637    9,755 SH       SOLE                  9,755      0    0
PEPSICO INC                  COM            713448108      684   10,473 SH       DEFINED              10,473      0    0






                                                  FORM 13F INFORMATION TABLE

          COLUMN 1              COLUMN 2    COLUMN 3  COLUMN 4     COLUMN 5       COLUMN 6  COLUMN 7      COLUMN 8
---------------------------- -------------- --------- -------- ----------------- ---------- -------- -------------------
                                                       VALUE   SHRS OR  SH/ PUT/ INVESTMENT  OTHER    VOTING AUTHORITY
       NAME OF ISSUER        TITLE OF CLASS   CUSIP   (x$1000) PRN AMT  PRN CALL DISCRETION MANAGERS  SOLE   SHARED NONE
---------------------------- -------------- --------- -------- -------- --- ---- ---------- -------- ------- ------ ----
                                                                                   
PFIZER INC                   COM            717081103    1,036   59,169 SH       SOLE                 59,169      0    0
PFIZER INC                   COM            717081103    1,041   59,437 SH       DEFINED              59,437      0    0
PHILIP MORRIS INTL INC       COM            718172109    1,115   19,050 SH       SOLE                 19,050      0    0
PHILIP MORRIS INTL INC       COM            718172109      430    7,342 SH       DEFINED               7,342      0    0
PROCTER & GAMBLE CO          COM            742718109      608    9,446 SH       SOLE                  9,446      0    0
PROCTER & GAMBLE CO          COM            742718109      453    7,041 SH       DEFINED               7,041      0    0
PROTECTIVE LIFE CORP         COM            743674103    6,193  232,488 SH       SOLE                232,488      0    0
REGIONS FINANCIAL CORP NEW   COM            7591EP100      568   81,091 SH       SOLE                 81,091      0    0
ROYAL DUTCH SHELL PLC        SPONS ADR A    780259206      359    5,370 SH       SOLE                  5,370      0    0
SPDR SERIES TRUST            BRCLYS YLD ETF 78464A417       39      979 SH       SOLE                    979      0    0
SPDR SERIES TRUST            BRCLYS YLD ETF 78464A417      265    6,675 SH       DEFINED               6,675      0    0
SARA LEE CORP                COM            803111103      144    8,225 SH       SOLE                  8,225      0    0
SARA LEE CORP                COM            803111103       67    3,800 SH       DEFINED               3,800      0    0
SCHLUMBERGER LTD             COM            806857108      272    3,253 SH       SOLE                  3,253      0    0
SCHLUMBERGER LTD             COM            806857108      124    1,490 SH       DEFINED               1,490      0    0
SPACE PROPULSION SYS INC     COM            846192102        0   16,250 SH       SOLE                 16,250      0    0
TARGET CORP                  COM            87612E106       80    1,326 SH       SOLE                  1,326      0    0
TARGET CORP                  COM            87612E106      122    2,035 SH       DEFINED               2,035      0    0
3M CO                        COM            88579Y101      588    6,813 SH       SOLE                  6,813      0    0
3M CO                        COM            88579Y101      393    4,558 SH       DEFINED               4,558      0    0
TRAVELERS COMPANIES INC      COM            89417E109        3       45 SH       SOLE                     45      0    0
TRAVELERS COMPANIES INC      COM            89417E109      246    4,421 SH       DEFINED               4,421      0    0
UNITED TECHNOLOGIES CORP     COM            913017109      262    3,330 SH       SOLE                  3,330      0    0
UNITED TECHNOLOGIES CORP     COM            913017109      469    5,955 SH       DEFINED               5,955      0    0
UNITEDHEALTH GROUP INC       COM            91324P102      209    5,800 SH       SOLE                  5,800      0    0
UNITEDHEALTH GROUP INC       COM            91324P102       29      800 SH       DEFINED                 800      0    0
VERIZON COMMUNICATIONS INC   COM            92343V104      707   19,757 SH       SOLE                 19,757      0    0
VERIZON COMMUNICATIONS INC   COM            92343V104      879   24,565 SH       DEFINED              24,565      0    0
WAL MART STORES INC          COM            931142103      943   17,486 SH       SOLE                 17,486      0    0
WAL MART STORES INC          COM            931142103      367    6,800 SH       DEFINED               6,800      0    0
WASHINGTON REAL ESTATE INVT  SH BEN INT     939653101      174    5,599 SH       SOLE                  5,599      0    0
WASHINGTON REAL ESTATE INVT  SH BEN INT     939653101      102    3,300 SH       DEFINED               3,300      0    0
WELLS FARGO & CO NEW         COM            949746101      449   14,476 SH       SOLE                 14,476      0    0
WELLS FARGO & CO NEW         COM            949746101      224    7,228 SH       DEFINED               7,228      0    0