Silence Therapeutics plc (Nasdaq: SLN), a global clinical-stage biotechnology company developing novel siRNA (short interfering RNA) therapies, today announced that management will participate in the following conferences and invited investors to participate by webcast.

• Cantor Global Healthcare Conference 2026
  Fireside chat on Wednesday, September 9, 2026 at 10:55 a.m. ET

• H.C. Wainwright 28th Annual Global Investment Conference
  Fireside chat on Tuesday, September 15, 2026 at 3:00 p.m. ET

• Morgan Stanley 24th Annual Global Healthcare Conference
  Fireside chat on Wednesday, September 16, 2026 at 8:30 a.m. ET

The live webcast can be accessed in the Investors section of the Silence website at www.silence-therapeutics.com/events. An archived replay of the webcast will be available following the conference.

About Silence Therapeutics

Silence Therapeutics is a global clinical-stage biotechnology company committed to transforming people’s lives by silencing diseases through precision engineered medicines created with proprietary siRNA (short interfering RNA) technology. Silence leverages its mRNAi GOLD™ platform to create innovative siRNA therapies designed to precisely target and silence genes that cause disease. The Company is advancing a growing pipeline of siRNA product candidates targeting areas of high unmet need across rare and common diseases where treatments are limited or inadequate. For more information, please visit https://www.silence-therapeutics.com/.

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