H&Q HEALTHCARE INVESTORS [LOGO] SEMIANNUAL REPORT MARCH 31, 2003 To our Shareholders: At quarter end on March 31, 2003, the net asset value per share of your Fund was $16.66. Total return for this quarter at net asset value was (1.9%), a change that lagged the Amex Biotech and NASDAQ Industrials Indices but which was favorable to the Dow Jones Industrial Average and the Russell 2000 Index for the same time period. Total return at market price was 0.21% during the quarter and 10.77% for the semi-annual period. Net asset value performance compared to the major indices for the quarter and six-month period ended March 31, 2003 was as follows: FISCAL YEAR TO DATE QUARTER ENDED 9/30/02 - 3/31/03 3/31/03 ------------------- ------------- Net Asset Value +1.0% -1.9% AMEX Biotech Index +4.2% -1.5% Dow Jones Industrial Average +5.3% -4.2% NASDAQ Industrials +9.3% -0.7% Russell 2000 +0.6% -4.8% The question, of course, is what can we expect from here. While we obviously don't know for certain, we believe that the recently completed quarter may signify a turning point. In the last few years we have been through a great deal of market turmoil. We saw a tremendous run up in market value in 2000, only to see a very significant and prolonged subsequent decline. As a benchmark, it is quite amazing to note that the NASDAQ Composite Index, which reached the 5000 level in 2000, was at 1341 at the close of the most recent quarter. This decline was punctuated along the way by a series of very tough blows to our collective psyche, including the September 11 attacks and last year's corporate governance crisis. During 2002 we detected a great deal of apprehension and even fear of the unknown in many investors. Entering the first quarter of 2003, geopolitical concerns were significant. As the quarter progressed, the focus of nearly the entire country rested on Iraq. A lot has changed in the last month or two. The scope and cost of loss in Iraq have been quantified. Importantly, the global and political worst-case scenarios have not come to pass. We are grateful and relieved about this, of course. And significantly, it looks to us that we have entered a more normal phase wherein performance of the economy and of individual companies could have a greater effect on the stock market and the share prices of individual companies. We think that there is an increasing likelihood that companies that 1 discover, develop and commercialize quality products will be rewarded with increased share price. Moreover, it appears to us that healthcare companies will be at the forefront of such a trend. We believe that all this bodes well for your Fund as we continue to identify innovative companies that may be able to cure recalcitrant diseases based on the application of novel scientific discoveries. Having said all this, we acknowledge that there are obviously other factors that could change this equation. As a general positive, we believe there is evidence that the economy is recovering, albeit slowly and with the creation of relatively few jobs. In recent months our view has been tempered by high corporate and household debt levels relative to income, concerns about employment, low savings rates, and by our sense of general public unease about the loss of paper wealth that has occurred in the last couple of years. However, more recently we have sensed a shift in the general mood of the public. It seems to us that after spending a month or more focused on the events in Iraq, the public is now looking forward rather than back. Importantly, a number of first quarter reports have met or exceeded expectations, including reports in the healthcare sector. This makes us more optimistic about the potential for progress in the next few quarters. We hope to see some modest improvement in the economy and particularly in the healthcare sector over the coming months. We are not sure how sustainable the current trends are - so we are not overly bullish - but we are certainly optimistic that 2003 will turn out to be a better year than the last two have proven to be. In this past quarter, we did not add any new private companies to the portfolio. We continue to evaluate a number of private investment opportunities, and have made new public purchases for the Fund. The Fund did, however, make follow-on investments in the following non-public companies in the portfolio: ACADIA Pharmaceuticals, CardioNet and Concentric Medical. As always, we encourage the Fund's shareholders to contact us with any questions or concerns they may have relating to the Fund, and hope to see you at the Annual Meeting of Shareholders on June 18th here in Boston. /s/ Alan G. Carr /s/ Daniel R. Omstead Alan G. Carr Daniel R. Omstead President Emeritus President 2 H&Q HEALTHCARE INVESTORS PRIVACY NOTICE If you are a registered shareholder of the Fund, the Fund and Hambrecht & Quist Capital Management, the Funds' investment adviser, may receive nonpublic personal information about you from the information collected by the transfer agent from your transactions in Fund shares. Any nonpublic personal information is not disclosed to third parties, except as permitted or required by law. In connection with servicing your account and effecting transactions, the information received may be shared with the investment adviser and non-affiliates, including transfer agents, custodians or other service companies. Access to your nonpublic personal information is restricted to employees who need to know that information to provide products or services to you. To maintain the security of your nonpublic personal information, physical, electronic, and procedural safeguards are in place that comply with federal standards. The policies and practices described above apply to both current and former shareholders. If your Fund shares are held in "street name" at a bank or brokerage, we do not have access to your personal information and you should refer to your bank's or broker's privacy policies for a statement of the treatment of your personal information. H&Q HEALTHCARE INVESTORS [CHART] PORTFOLIO AS OF MARCH 31, 2003 TOTAL VENTURE DIFFERENCE AGRI/ENVIRO 2% 2% 0% BIOTECHNOLOGY 48% 12% 36% CROs 1% 0% 1% DIAGNOSTICS 6% 4% 2% HEALTHCARE INFO SERVICES 4% 2% 2% MEDICAL SPECIALTY 14% 6% 8% MEDICAL SUPPLIES 2% 1% 0% PHARMACEUTICALS 5% 2% 3% LIQUID ASSETS 18% 0% 18% 3 H&Q HEALTHCARE INVESTORS LARGEST HOLDINGS AS OF MARCH 31, 2003 % OF NET ASSETS --------------- Martek Biosciences 5.31% Celgene 4.51% Gilead Sciences 3.77% MedImmune 3.57% CV Therapeutics 2.38% CardioNet (Restricted) 2.33% Cubist Pharmaceuticals 2.27% IDEXX Laboratories 2.24% Telik 2.10% Exelixis 2.06% H&Q HEALTHCARE INVESTORS SIGNIFICANT PORTFOLIO TRANSACTIONS QUARTER ENDED MARCH 31, 2003 UNITS HELD UNITS HELD 12/31/02 3/31/03 ---------- ---------- PURCHASES ACADIA Pharmaceuticals (Restricted) Series F 0 277,778 CardioNet (Restricted) 1,457,144 1,577,144 Charles River Labs 0 85,200 Concentric Medical (Restricted) 4,411,764 4,852,940 Eclipsys 0 142,200 IMPAX Laboratories 231,600 486,100 Kosan Biosciences 263,300 442,600 Lexicon Genetics 208,400 342,200 Millennium Pharmaceuticals 0 418,500 SALES Cytyc 324,330 0 Digene 18,500 0 Endologix 198,000 0 Gilead Sciences 426,636 213,000 4 H&Q HEALTHCARE INVESTORS SCHEDULE OF INVESTMENTS March 31, 2003 (UNAUDITED) SHARES VALUE --------- ------------ CONVERTIBLE SECURITIES - 29.8% OF NET ASSETS CONVERTIBLE PREFERRED (RESTRICTED) - 27.7% AGRICULTURAL/ENVIRONMENTAL TECHNOLOGIES - 1.7% 375,000 Ceres Series C* $ 2,250,000 27,443 Ceres Series C-1*# 164,658 277,967 Ceres Series D*# 1,667,801 222,222 EPR Series A* 22,222 BIOTECHNOLOGY - 11.4% 460,000 ACADIA Pharmaceuticals Series E* 1,242,000 277,778 ACADIA Pharmaceuticals Series F* 750,001 952,381 Agensys Series C* 3,000,000 2,380,953 Agilix Series B* 3,000,001 850,436 Avalon Pharmaceuticals Series B* 2,999,998 1,212,709 IDUN Pharmaceuticals Series A-1* 3,000,000 1,818,182 Raven biotechnologies Series B*^ 1,509,091 2,809,157 Raven biotechnologies Series C*^ 2,331,600 47,407 Therion Biologics Series A* 89,125 240,000 Therion Biologics Series B*# 451,200 407,712 Therion Biologics Series C*# 766,499 36,092 Therion Biologics Sinking Fund* 67,853 1,750,000 Triad Therapeutics Series A* 1,750,000 525,000 Triad Therapeutics Series B* 525,000 1,200,000 Triad Therapeutics Series C* 1,200,000 923,077 Zyomyx Series B* 1,846,153 600,000 Zyomyx Series C* 1,200,000 600,000 Zyomyx Series E* 1,200,000 DIAGNOSTICS - 3.3% 1,577,144 CardioNet Series C*^ 5,520,004 484,829 CytoLogix Series A*^ 400,178 227,130 CytoLogix Series B*#^ 187,472 160,000 Masimo Series D* 1,760,000 HEALTHCARE INFORMATION SERVICES - 1.8% 5,384,615 PHT Series D*^ 4,200,000 MEDICAL SPECIALTY - 6.3% 636,364 AbTox Series F*+ 6,364 4,852,940 Concentric Medical Series B* 3,299,999 1,632,653 OmniSonics Medical Technologies Series B*^ 2,400,000 1,034,519 Senomyx Series E* 3,000,002 639,659 Songbird Hearing Series D* 6,397 652,173 TherOx Series H* 1,976,084 820,313 VNUS Medical Technologies Series E*^ 4,200,003 MEDICAL SUPPLIES - 1.4% 343,750 LocalMed Series D* 3,438 631,580 Novacept Series G*# 2,178,951 347,826 Novacept Series H* 1,200,000 The accompanying notes are an integral part of these financial statements. 5 SHARES VALUE ---------- ------------ CONVERTIBLE SECURITIES - CONTINUED CONVERTIBLE PREFERRED (RESTRICTED) - 27.7% PHARMACEUTICALS/DRUG DELIVERY - 1.8% 139,873 Galileo Laboratories Series F* $ 489,555 211,765 Theravance Series C* 1,905,885 200,000 Theravance Series D-1* 1,800,000 ------------ $ 65,567,534 ------------ PRINCIPAL AMOUNT ---------- CONVERTIBLE BONDS AND NOTES - 2.1% BIOTECHNOLOGY - 1.9% $6,800,000 CuraGen 6% Cvt. Deb. due 2007~ $ 4,624,000 DIAGNOSTICS - 0.1% 168,336 CytoLogix (Restricted) 6.75% Cvt. Note, due 2003*^ 168,337 HEALTHCARE INFORMATION SERVICES - 0.0% 1,577,366 FitForAll.com (Restricted) 10% Prom. Note*#+ 158 MEDICAL SPECIALTY - 0.1% 180,000 AbTox (Restricted) 12% Prom. Note*+ 180,000 ------------ $ 4,972,495 ------------ TOTAL CONVERTIBLE SECURITIES (Cost $91,868,175) $ 70,540,029 ------------ SHARES ---------- COMMON STOCKS - 52.0% AGRICULTURAL/ENVIRONMENTAL TECHNOLOGY - 0.1% 71,483 Catalytica Energy Systems* $ 182,282 ------------ 182,282 ------------ BIOTECHNOLOGY - 34.5% BIOPHARMACEUTICALS - 25.1% 311,300 Adolor* 3,084,983 429,898 BioTransplant* 64,485 2,760 BioTransplant (Restricted) Warrants (expire 8/12/04)* 0 6,300 BioTransplant (Restricted) Warrants (expire 10/31/04)* 0 1,150 BioTransplant (Restricted) Warrants (expire 8/15/05)* 76 410,400 Celgene* 10,703,232 441,471 Corixa* 3,019,662 33,164 Corixa Warrants (expire 8/14/07)* 16,482 The accompanying notes are an integral part of these financial statements. 6 SHARES VALUE ---------- ------------ BIOTECHNOLOGY - CONTINUED 550,556 Cubist Pharmaceuticals* $ 4,409,954 200,001 Cubist Pharmaceuticals (Restricted) Warrants (expire 9/23/03)* 979,205 312,823 CV Therapeutics* 5,640,199 83,000 Genzyme* 3,025,350 213,000 Gilead Sciences* 8,943,870 442,600 Kosan Biosciences* 1,973,996 258,000 MedImmune* 8,470,140 226,760 Therion Biologics (Restricted)* 426,309 264,912 Transkaryotic Therapies* 1,568,279 270,270 Tularik* 1,364,863 113,700 Vertex Pharmaceuticals* 1,264,344 418,165 Vicuron Pharmaceuticals* 4,528,727 18,696 Vicuron Pharmaceuticals (Restricted) Warrants (expire 8/3/05)* 91,386 GENOMICS/DRUG DISCOVERY - 9.4% 297,000 Abgenix* 2,583,900 933,000 deCODE Genetics* 1,726,050 387,802 Dyax* 674,775 732,600 Exelixis* 4,879,116 342,200 Lexicon Genetics* 1,365,378 170,142 Lynx Therapeutics* 304,554 386,400 Lynx Therapeutics Warrants (expire 4/29/07)* 0 418,500 Millennium Pharmaceuticals* 3,289,410 174,461 Molecular Devices* 2,110,978 616,100 Rigel Pharmaceuticals* 455,914 370,237 Telik* 4,975,985 ------------ 81,941,602 ------------ CONTRACT RESEARCH ORGANIZATIONS - 1.4% 85,200 Charles River Labs* 2,174,304 91,400 Quintiles Transnational* 1,111,424 ------------ 3,285,728 ------------ DIAGNOSTICS - 2.7% 522,617 Biofield* 141,107 600,000 Biofield (Restricted)* 129,600 152,000 IDEXX Laboratories* 5,315,440 160,000 Masimo Labs (Restricted)* 1,600 685,621 Sontra Medical (Restricted)*^ 795,320 ------------ 6,383,067 ------------ The accompanying notes are an integral part of these financial statements. 7 SHARES VALUE ---------- ------------ HEALTHCARE INFORMATION SERVICES - 2.2% 142,200 Eclipsys* $ 1,133,476 454,500 WebMD* 4,099,590 306,208 Syntiro Healthcare Services (Restricted)* 3,062 188,096 Syntiro Healthcare Services (Restricted) Warrants (expire 10/15/04)* 0 ------------ 5,236,128 ------------ MEDICAL SPECIALTY - 7.9% 101,848 Biopure Class A* 340,172 8,333 Biopure (Restricted) Warrants (expire 8/4/03)* 0 1,000,000 Endocardial Solutions*^ 2,770,000 441,409 Martek Biosciences* 12,588,985 1,020,000 Orthovita*^ 3,060,000 ------------ 18,759,157 ------------ MEDICAL SUPPLIES - 0.5% 645,000 EP MedSystems* 1,070,700 ------------ 1,070,700 ------------ PHARMACEUTICALS/DRUG DELIVERY - 2.7% 225,000 Aradigm* 281,250 486,100 IMPAX Laboratories* 2,182,589 326,600 IVAX* 4,000,850 ------------ 6,464,689 ------------ TOTAL COMMON STOCKS (Cost $101,988,449) $123,323,353 ------------ PRINCIPAL AMOUNT ---------- TEMPORARY CASH INVESTMENTS - 13.2% $ 9,800,000 General Electric Capital Corp., 1.24%, due 4/16/03 $ 9,794,937 21,500,000 U.S. Treasury Bill, 1.10%, due 4/10/03 21,494,087 ------------ TOTAL TEMPORARY CASH INVESTMENTS (Cost $31,289,024) $ 31,289,024 ------------ TOTAL INVESTMENTS (Cost $225,145,648) $225,152,406 ============ ---------- * Non income-producing security. # With warrants attached. ^ Affiliated issuers in which the Fund holds 5% or more of the voting securities (Total Value of $27,542,005). ~ Security exempt from registration under Rule 144A of the Securities Act of 1933. These securities may be resold in transactions exempt from registration, normally to qualified institutional buyers. + Issuer filed for bankruptcy. The accompanying notes are an integral part of these financial statements. 8 H&Q HEALTHCARE INVESTORS STATEMENT OF ASSETS AND LIABILITIES March 31, 2003 (UNAUDITED) ASSETS: Investments, at value (identified cost $225,145,648; see Schedule of Investments) $ 225,152,406 Cash 2,066,024 Interest receivable 76,367 Receivable for investments sold 10,153,863 Prepaid expenses 36,390 ------------- Total assets $ 237,485,050 ------------- LIABILITIES: Accrued advisory fee $ 261,532 Accrued other 151,200 ------------- Total liabilities $ 412,732 ------------- NET ASSETS $ 237,072,318 ============= SOURCES OF NET ASSETS: Shares of beneficial interest, par value $.01 per share, unlimited number of shares authorized, amount paid in on 14,227,676 shares issued and outstanding $ 228,358,122 Accumulated net investment loss (1,413,618) Accumulated net realized gain on investments 10,121,056 Net unrealized gain on investments 6,758 ------------- Total net assets (equivalent to $16.66 per share based on 14,227,676 shares outstanding) $ 237,072,318 ============= The accompanying notes are an integral part of these financial statements. 9 H&Q HEALTHCARE INVESTORS STATEMENT OF OPERATIONS For the Six Months Ended March 31, 2003 (UNAUDITED) INVESTMENT INCOME: Dividend income (net of foreign tax of $606) $ 2,583 Interest income 521,948 ----------- Total investment income $ 524,531 EXPENSES: Advisory fees $ 1,612,744 Legal fees 37,953 Shareholder reporting 40,847 Trustees' fees and expenses 72,123 Custodian fees 49,775 Transfer agent fees 26,903 Stock exchange listing fee 29,831 Accounting and auditing fees 39,550 Other 28,423 ----------- Total expenses 1,938,149 ------------ Net investment loss $ (1,413,618) ------------ NET REALIZED AND UNREALIZED GAIN (LOSS) ON INVESTMENTS: Net realized gain on investments $ 13,732,359 Decrease in net unrealized gain on investments (10,854,871) ------------ Net gain on investments $ 2,877,488 ------------ Net increase in net assets resulting from operations $ 1,463,870 ============ The accompanying notes are an integral part of these financial statements. 10 H&Q HEALTHCARE INVESTORS STATEMENTS OF CHANGES IN NET ASSETS FOR THE SIX FOR THE MONTHS ENDED YEAR ENDED MARCH 31, 2003 SEPTEMBER 30, (UNAUDITED) 2002 -------------- ------------- NET INCREASE (DECREASE) IN NET ASSETS RESULTING FROM OPERATIONS: Net investment loss $ (1,413,618) $ (3,593,224) Net realized gain on investments 13,732,359 33,875,011 Decrease in net unrealized gain on investments (10,854,871) (106,220,050) -------------- ------------- Net increase (decrease) in net assets resulting from operations $ 1,463,870 $ (75,938,263) -------------- ------------- DISTRIBUTIONS TO SHAREHOLDERS FROM: Net realized capital gains $ (19,552,950) $ (39,468,231) -------------- ------------- CAPITAL SHARE TRANSACTIONS: Value of shares issued in reinvestment of distributions (904,193 and 1,281,419 shares, respectively) $ 13,155,620 $ 28,039,066 -------------- ------------- Net decrease in net assets $ (4,933,460) $ (87,367,428) NET ASSETS: Beginning of period 242,005,778 329,373,206 -------------- ------------- End of period $ 237,072,318 $ 242,005,778 ============== ============= The accompanying notes are an integral part of these financial statements. 11 H&Q HEALTHCARE INVESTORS STATEMENT OF CASH FLOWS For the Six Months Ended March 31, 2003 (UNAUDITED) CASH FLOWS USED FOR OPERATING ACTIVITIES: Interest income received $ 456,227 Dividends received 2,583 Operating expenses paid (2,000,494) ------------- Net cash used for operating activities $ (1,541,684) ------------- CASH FLOWS PROVIDED FROM INVESTING ACTIVITIES Purchases of portfolio securities $ (23,811,686) Net maturities of temporary cash investments 16,385,769 Sales and maturities of portfolio securities 17,388,136 ------------- Net cash provided from investing activities $ 9,962,219 ------------- CASH FLOWS USED FOR FINANCING ACTIVITIES: Cash distributions paid, net $ (6,397,330) ------------- Net cash used for financing activities $ (6,397,330) ------------- NET INCREASE IN CASH $ 2,023,205 CASH AT BEGINNING OF PERIOD 42,819 ------------- CASH AT END OF PERIOD $ 2,066,024 ============= RECONCILIATION OF NET INCREASE IN NET ASSETS RESULTING FROM OPERATIONS TO NET CASH USED FOR OPERATING ACTIVITIES: Net increase in net assets resulting from operations $ 1,463,870 Accretion of discount (56,221) Net realized gain on investments (13,732,359) Net decrease in unrealized gain on investments 10,854,871 Increase in interest receivable (9,500) Increase in prepaid expenses (6,975) Decrease in accrued expenses (55,370) ------------- Net cash used for operating activities $ (1,541,684) ============= Noncash financing activities not included herein consist of stock distributions of $13,155,620. The accompanying notes are an integral part of these financial statements. 12 H&Q HEALTHCARE INVESTORS FINANCIAL HIGHLIGHTS (SELECTED DATA FOR EACH SHARE OF BENEFICIAL INTEREST OUTSTANDING THROUGHOUT THE PERIOD INDICATED) FOR THE SIX MONTHS ENDED FOR THE YEARS ENDED SEPTEMBER 30, MARCH 31, 2003 ------------------------------------------------------------------------------- (UNAUDITED) 2002(1) 2001 2000 1999 1998 ------------ ------------ ------------ ------------ ------------ ------------ Net asset value per share: Beginning of period $ 18.160 $ 27.350 $ 46.147 $ 21.771 $ 16.711 $ 23.106 ------------ ------------ ------------ ------------ ------------ ------------ Net investment loss $ (0.103)(2) $ (0.283)(2) $ (0.195)(2) $ (0.290) $ (0.176) $ (0.217) Net realized and unrealized gain (loss) on investments 0.053 (5.727) (13.822) 28.131 5.596 (5.108) ------------ ------------ ------------ ------------ ------------ ------------ Total increase (decrease) from investment operations $ (0.050) $ (6.010) $ (14.017) $ 27.841 $ 5.420 $ (5.325) ------------ ------------ ------------ ------------ ------------ ------------ Capital gains distributions to shareholders $ (1.450) $ (3.180) $ (4.780) $ (3.465) $ (0.360) $ (1.070) ------------ ------------ ------------ ------------ ------------ ------------ Net asset value per share: End of period $ 16.660 $ 18.160 $ 27.350 $ 46.147 $ 21.771 $ 16.711 ============ ============ ============ ============ ============ ============ Per share market value: End of period $ 14.180 $ 14.100 $ 21.740 $ 36.188 $ 16.313 $ 13.125 Total investment return at market value 10.77% (25.24%) (27.23%) 151.66% 27.39% (26.05%) RATIOS AND SUPPLEMENTAL DATA: Net assets at end of period $237,072,318 $242,005,778 $329,373,206 $485,582,570 $209,519,627 $157,976,073 Ratio of operating expenses to average net assets 1.63%* 1.64% 1.42% 1.45% 1.46% 1.46% Ratio of net investment loss to average net assets (1.19%)* (1.16%) (0.62%) (0.86%) (0.91%) (1.11%) Portfolio turnover rate 11.90% 17.40% 16.17% 12.90% 24.88% 17.15% Number of shares outstanding at end of period 14,227,676 13,323,483 12,042,064 10,522,490 9,623,524 9,453,317 (1) The Fund adopted the provisions of the AICPA Audit and Accounting Guide for Investment Companies and began accreting discounts and amortizing premiums on all debt securities. The effect of this change for the year ended September 30, 2002 was a decrease in net investment loss per share of $.009, an increase in net realized and unrealized loss on investments per share of $.009, and a decrease in the ratio of net investment loss to average net assets from (1.20%) to (1.16%). Per share data and ratios for the periods prior to October 1, 2001 have not been restated to reflect this change in presentation. (2) Net investment loss per share has been computed using average shares outstanding. * Annualized. The accompanying notes are an integral part of these financial statements. 13 H&Q HEALTHCARE INVESTORS NOTES TO FINANCIAL STATEMENTS March 31, 2003 (UNAUDITED) (1) ORGANIZATION H&Q Healthcare Investors (the Fund) is a Massachusetts business trust registered under the Investment Company Act of 1940 as a diversified closed-end management investment company. The Fund's investment objective is long-term capital appreciation through investment in securities of companies in the healthcare industries. The Fund invests primarily in securities of public and private companies that are believed to have significant potential for above-average growth. The Fund was organized on October 31, 1986 and commenced operations on April 22, 1987. The preparation of these financial statements requires the use of certain estimates by management in determining the entity's assets, liabilities, revenues and expenses. Actual results could differ from these estimates. The following is a summary of significant accounting policies consistently followed by the Fund, which are in conformity with those generally accepted in the United States of America. INVESTMENT SECURITIES Investments traded on national securities exchanges or in the over-the-counter market that are National Market System securities are valued at the last sale price or, lacking any sales, at the mean between the last bid and asked prices. Other over-the-counter securities are valued at the most recent bid prices as obtained from one or more dealers that make markets in the securities. As indicated in Note 4, investments for which market quotations are not readily available are valued at fair value as determined in good faith by the Trustees of the Fund. Temporary cash investments with maturity of 60 days or less are valued at amortized cost. Investment transactions are recorded on a trade date basis. Gains and losses from sales of investments are recorded using the "identified cost" method. Interest income is recorded on the accrual basis, adjusted for amortization of premiums and accretion of discounts. Dividend income is recorded on the ex-dividend date. FEDERAL INCOME TAXES It is the Fund's policy to comply with the requirements of the Internal Revenue Code applicable to regulated investment companies and to distribute to its shareholders substantially all of its taxable income and its net realized capital gains, if any. Therefore, no Federal income or excise tax provision is required. DISTRIBUTIONS The Fund records all distributions to shareholders from net investment income, if any, and realized gains on the ex-dividend date. Such distributions are determined in conformity with income tax regulations. Due to permanent book/tax differences in accounting for certain transactions, certain distributions may be treated as distributions from capital as opposed to distributions of net investment income or realized capital gains. DISTRIBUTION POLICY The current distribution policy is to declare distributions in stock. Stock distributions will automatically be paid in newly issued shares of the Fund unless otherwise instructed by the shareholder. Pursuant to an SEC exemptive order, the Fund has implemented a fixed distribution policy that permits the Fund to make quarterly distributions at a rate of 2% of the Fund's net assets to shareholders of record. The Fund intends to use net realized capital gains when making quarterly distributions. This could result in a return of capital to shareholders if the amount of the distribution exceeds the Fund's net investment income and realized capital gains. 14 It is anticipated that net realized capital gains in excess of the total distributed under this policy would be included in the December distribution. STATEMENT OF CASH FLOWS The cash amount shown in the Statement of Cash Flows is the amount included in the Fund's Statement of Assets and Liabilities and represents cash on hand at its custodian and does not include temporary cash investments at March 31, 2003. (2) SECURITIES TRANSACTIONS The aggregate cost of purchases and proceeds from sales of investment securities (other than temporary cash investments) for the six months ended March 31, 2003 totaled $23,811,686 and $25,868,376, respectively. At March 31, 2003, the total cost of securities for Federal income tax purposes was $225,145,648. The net unrealized gain on securities held by the Fund was $6,758, including gross unrealized gain of $59,417,969 and gross unrealized loss of $59,411,211. (3) INVESTMENT ADVISORY FEES AND OTHER TRANSACTIONS WITH AFFILIATES The Fund has entered into an Investment Advisory Agreement (the Advisory Agreement) with Hambrecht & Quist Capital Management LLC (the Adviser). Pursuant to the terms of the Advisory Agreement, the Fund pays the Adviser a monthly fee at the rate when annualized of (i) 2.5% of the average net assets for the month of its venture capital and other restricted securities up to 25% of net assets and (ii) for the month, for all other assets, 1.0% of the average net assets up to $250 million, 0.9% of the average net assets for the next $250 million, 0.8% of the average net assets for the next $500 million and 0.7% of the average net assets thereafter. The aggregate fee may not exceed a rate when annualized of 1.375%. Certain officers and Trustees of the Fund are also officers of the Adviser. Trustees who are not affiliates of the Adviser receive an annual fee of $15,000 plus $1,500 for each meeting attended. (4) VENTURE CAPITAL AND OTHER RESTRICTED SECURITIES The Fund may invest in venture capital and other restricted securities if these securities would currently comprise 40% or less of net assets. The value of these securities represents 29% of the Fund's net assets at March 31, 2003. The value of the venture capital and other restricted securities is determined in good faith by the Trustees. However, because of the inherent uncertainty of valuations, these estimated values may differ significantly from the values that would have been used had a ready market for the securities existed, and the differences could be material. During the six-month period ended March 31, 2003, the Fund sold restricted securities for cash and a proportionate interest in a 5% interest-bearing promissory note due October 31, 2004. The Fund's interest in the note has a par value of $121,200 whose estimated value of $60,000 at March 31, 2003 has also been determined by the Trustees and which is included in the Receivable for Investments Sold in the Statement of Assets and Liabilities. 15 The following table details the acquisition date, cost, carrying value per unit, and value of the Fund's venture capital and other restricted securities at March 31, 2003, as determined by the Trustees of the Fund. ACQUISITION CARRYING VALUE SECURITY DATE COST PER UNIT VALUE ------------------------------------ --------------- ----------- -------------- ----------- AbTox Series F Cvt. Pfd. 3/7/97 $ 1,463,562 $ 0.010 $ 6,364 12% Promissory Note 2/26/98-3/26/98 180,000 1.000 180,000 ACADIA Pharmaceuticals Series E Cvt. Pfd. 5/2/00-3/24/03 3,000,594 2.700 1,242,000 Series F Cvt. Pfd. 3/19/03 750,001 2.700 750,001 Agensys Series C Cvt. Pfd. 2/14/02 3,005,073 3.150 3,000,000 Agilix Series B Cvt. Pfd. 11/8/01 3,014,260 1.260 3,000,001 Avalon Pharmaceuticals Series B Cvt. Pfd. 10/22/01 3,008,325 3.528 2,999,998 Biofield Common 12/15/00 302,984 0.216 129,600 Biopure Common Warrants (expire 8/4/03) 5/13/99 0 0.000 0 BioTransplant Common Warrants (expire 8/12/04) 8/12/94 0 0.000 0 Common Warrants (expire 10/31/04) 10/31/94 0 0.000 0 Common Warrants (expire 8/15/05) 8/18/95 0 0.066 76 CardioNet^ Series C Cvt. Pfd. 5/3/01-3/25/03 5,546,931 3.500 5,520,004 Ceres Series C Cvt. Pfd. 12/23/98 1,502,620 6.000 2,250,000 Series C-1 Cvt. Pfd.* 1/4/01 111,488 6.000 164,658 Series D Cvt. Pfd.* 3/14/01 1,668,122 6.000 1,667,801 Concentric Medical Series B Cvt. Pfd. 5/7/02-1/24/03 3,328,055 0.680 3,299,999 Cubist Pharmaceuticals Common Warrants (expire 9/23/03) 9/23/98 235 4.896 979,205 CytoLogix^ Series A Cvt. Pfd. 1/13/98-7/21/99 2,332,441 0.825 400,178 Series B Cvt. Pfd.* 1/11/01 1,153,658 0.825 187,472 Cvt. Note 5/29/02 168,337 1.000 168,337 EPR Series A Cvt. Pfd. 3/9/94 1,000,409 0.100 22,222 FitForAll.com 10% Promissory Note* 2/22/00-9/18/00 1,613,493 0.010 158 Galileo Laboratories Series F Cvt. Pfd. 8/18/00 3,002,319 3.500 489,555 IDUN Pharmaceuticals Series A-1 Cvt. Pfd. 11/26/02 3,001,966 2.474 3,000,000 LocalMed Series D Cvt. Pfd. 2/9/96 1,376,970 0.010 3,438 16 ACQUISITION CARRYING VALUE SECURITY DATE COST PER UNIT VALUE ------------------------------------ ---------------- ------------ -------------- ------------ Masimo Series D Cvt. Pfd. 8/14/96 $ 1,120,040 $ 11.000 $ 1,760,000 Masimo Labs Common 8/14/96 0 0.010 1,600 Novacept Series G Cvt. Pfd.* 3/27/01 3,001,927 3.450 2,178,951 Series H Cvt. Pfd. 4/25/02 1,200,000 3.450 1,200,000 Omnisonics Medical Technologies^ Series B Cvt. Pfd. 5/24/01 2,404,472 1.470 2,400,000 PHT^ Series D Cvt. Pfd. 7/23/01 4,200,000 0.780 4,200,000 Raven biotechnologies^ Series B Cvt. Pfd. 12/12/00 3,001,725 0.830 1,509,091 Series C Cvt. Pfd. 11/26/02 2,331,600 0.830 2,331,600 Senomyx Series E Cvt. Pfd. 2/19/02 3,003,903 2.900 3,000,002 Songbird Hearing Series D Cvt. Pfd. 12/14/00 3,004,861 0.010 6,397 Sontra Medical^ Common 6/24/02 1,679,749 1.160 795,320 Syntiro Heathcare Services Common 2/5/97 1,200,325 0.010 3,062 Warrants (expire 10/15/04) 10/15/98 0 0.000 0 Theravance Series C Cvt. Pfd. 2/5/99 1,800,123 9.000 1,905,885 Series D-1 Cvt. Pfd. 8/28/00 1,800,900 9.000 1,800,000 Therion Biologics Common 7/12/90-10/16/96 511,365 1.880 426,309 Series A Cvt. Pfd. 8/20/96-10/16/96 444,850 1.880 89,125 Series B Cvt. Pfd.* 2/24/99-6/22/99 900,914 1.880 451,200 Series C Cvt. Pfd.* 9/26/01 1,528,922 1.880 766,499 Sinking Fund Cvt. Pfd. 10/17/94-4/3/96 721,291 1.880 67,853 TherOx Series H Cvt. Pfd. 9/11/00 3,001,873 3.030 1,976,084 Triad Therapeutics Series A Cvt. Pfd. 6/8/99 1,751,170 1.000 1,750,000 Series B Cvt. Pfd. 12/20/00 1,053,135 1.000 525,000 Series C Cvt. Pfd. 11/25/02 1,200,000 1.000 1,200,000 Vicuron Pharmaceuticals Warrants (expire 8/3/05) 6/28/99 905 4.888 91,386 VNUS Medical Technologies^ Series E Cvt. Pfd. 8/20/01 4,200,003 5.120 4,200,003 Zyomyx Series B Cvt. Pfd. 2/19/99 1,200,550 2.000 1,846,153 Series C Cvt. Pfd. 3/2/00 1,200,690 2.000 1,200,000 Series E Cvt. Pfd. 7/22/02 1,200,000 2.000 1,200,000 ------------ ------------ $ 89,197,136 $ 68,342,587 ============ ============ * With warrants attached. ^ Affiliated issuers. 17 H&Q HEALTHCARE INVESTORS New York Stock Exchange Symbol: HQH 30 Rowes Wharf, 4th Floor Boston, Massachusetts 02110-3328 (617) 772-8500 www.hqcm.com OFFICERS Daniel R. Omstead, ENGSCD, President Alan G. Carr, President Emeritus Kimberley L. Carroll, Treasurer Jennifer L. Morris, Secretary TRUSTEES Alan G. Carr Lawrence S. Lewin Robert P. Mack, M.D. Eric Oddleifson Oleg M. Pohotsky Uwe E. Reinhardt, Ph.D. Henri A. Termeer INVESTMENT ADVISER Hambrecht & Quist Capital Management LLC CUSTODIAN AND TRANSFER AGENT State Street Bank and Trust Company INDEPENDENT ACCOUNTANTS PricewaterhouseCoopers LLP LEGAL COUNSEL Dechert LLP ---------- Shareholders with questions regarding share transfers may call 1-800-426-5523 Interim daily net asset value may be obtained from our website (www.hqcm.com) or by calling 1-800-451-2597 For copies of the Fund's DIVIDEND REINVESTMENT PLAN, please contact the Plan Agent, State Street Bank & Trust Co. P.O. Box 8200, Boston, MA 02266-8200 Telephone: 1-800-426-5523 ---------- Out of concern for the environment and in an effort to reduce Fund expenses, this report is printed on recycled paper. HQHCM-SAR-03