FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Blackford Quentin S.   2. Issuer Name and Ticker or Trading Symbol NUVASIVE INC [NUVA] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) CFO and CAO (Last) (First) (Middle) 7475 LUSK BLVD. 3. Date of Earliest Transaction (Month/Day/Year) 02/01/2016 (Street) SAN DIEGO, CA 92121 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 02/01/2016   M   1,250 A $ 0 7,427 (1) D   Common Stock 02/01/2016   M   5,339 A $ 0 12,766 (1) D   Common Stock 02/01/2016   M   3,193 A $ 0 15,959 (1) D   Common Stock 02/01/2016   F   3,674 (2) D $ 46.6 12,285 (1) D

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

RSUs (3)

$ 0

02/01/2016

M

1,250

(4)

(4)

Common Stock

1,250

$ 0

0

D

RSUs (3)

$ 0

02/01/2016

M

5,339

(5)

(5)

Common Stock

5,339

$ 0

5,339

D

PRSUs (6)

$ 0

01/26/2016

M

3,193

(7)

(7)

Common Stock

3,193

$ 0

9,576

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Blackford Quentin S. 7475 LUSK BLVD. SAN DIEGO, CA 92121			CFO and CAO

Signatures

/s/ Jason M. Hannon, Attorney-in-Fact for Quentin Blackford		02/03/2016
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Shares directly held by the Reporting Person. The Reporting Person also holds conditional rights to receive shares pursuant to previously disclosed Issuer equity awards.
(2)	Shares withheld by the Issuer to satisfy tax withholding obligations.
(3)	Each Restricted Stock Unit ("RSU") represents the right to receive one share of the Issuer's common stock upon vesting.
(4)	This RSU award was granted to the Reporting Person on February 27, 2012. In accordance with the terms of the RSU award, the award vested as to 1,250 shares on each of February 1, 2013, February 1, 2014, February 1, 2015 and February 1, 2016.
(5)	This RSU award was granted to the Reporting Person on February 26, 2013. In accordance with the terms of the RSU award, the award vested as to 5,340 shares on February 1, 2014, 5,399 shares on each of February 1, 2015 and February 1, 2016 and will vest as to 5,399 shares February 1, 2017.
(6)	Each Performance Restricted Stock Unit ("PRSU") represents the right to receive one share of the Issuer's common stock upon vesting.
(7)	This PRSU award was granted to the Reporting Person on February 17, 2015. In accordance with the terms of the PRSU award, the award vested as to 3,193 shares on February 1, 2016 and will vest as to 3,192 shares on each of February 1, 2017, February 1, 2018 and February 1, 2019.

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