SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 ---------------------------- FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 ---------------------------- Date of Report (Date of earliest event reported): November 25, 2003 HYBRIDON, INC. -------------------------------------------------------------------------------- (Exact name of Registrant as Specified in its Charter) Delaware 0-027352 04-3072298 -------- -------- ---------- (State or Other Jurisdiction (Commission File Number (IRS Employer of Incorporation) Identification No.) 345 Vassar Street, Cambridge, Massachusetts 02139 -------------------------------------------------------------------------------- (Address of Principal Executive Offices) (Zip Code) Registrant's telephone number, including area code: (617) 679-5500 Not Applicable -------------------------------------------------------------------------------- (Former Name or Former Address if Changed Since Last Report) ITEM 5. OTHER EVENTS AND REQUIRED FD DISCLOSURE On November 25, 2003, Hybridon, Inc., a Delaware corporation ("Hybridon"), announced that its application to list its common stock on the American Stock Exchange (the "Exchange") had been approved. Hybridon expects that trading on the Exchange will begin at 9:30 a.m. on Friday, December 5, 2003. Hybridon's common stock will continue to trade on the Over the Counter Bulletin Board until that date. The Exchange approval is contingent upon Hybridon being in compliance with all applicable standards on the date it begins trading on the Exchange and may be rescinded if Hybridon is not in compliance with such standards. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Date: November 25, 2003 HYBRIDON, INC. /s/ Robert G. Andersen ----------------------------------- Robert G. Andersen Chief Financial Officer and Vice President of Operations