ATHEROGENICS, INC
Table of Contents

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549


FORM 10-Q


QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended June 30, 2003

Commission File No. 0-31261

ATHEROGENICS, INC.

(Exact name of registrant as specified in its charter)
     
Georgia   58-2108232

 
(State of incorporation)   (I.R.S. Employer Identification Number)

8995 Westside Parkway, Alpharetta, Georgia 30004


(Address of registrant’s principal executive offices, including zip code)


(Registrant’s telephone number, including area code): (678) 336-2500

     Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.   Yes x    No o

     Indicate by check mark whether the registrant is an accelerated filer (as defined in Rule 12b-2 of the Act).   Yes x    No o

     As of August 8, 2003, there were 36,533,448 shares of the registrant’s common stock outstanding.


 


TABLE OF CONTENTS

PART I — FINANCIAL INFORMATION
Item 1. Financial Statements
CONDENSED BALANCE SHEETS
CONDENSED STATEMENTS OF OPERATIONS
CONDENSED STATEMENTS OF CASH FLOWS
NOTES TO CONDENSED FINANCIAL STATEMENTS
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
Item 3. Quantitative And Qualitative Disclosures About Market Risk
Item 4. Controls and Procedures
PART II — OTHER INFORMATION
Item 4. Submission of Matters to a Vote of Security Holders
Item 6. Exhibits and Reports on Form 8-K
SIGNATURES
EX-10.23 LOAN MODIFICATION AGREEMENT DATED 6/20/03
EX-31 SECTION 302 CERTIFICATIONS
EX-32 SECTION 906 CERTIFICATIONS


Table of Contents

ATHEROGENICS, INC.
FORM 10-Q
INDEX

           
      Page No.
     
PART I. FINANCIAL INFORMATION
       
Item 1. Financial Statements (unaudited)
       
 
Condensed Balance Sheets June 30, 2003 and December 31, 2002
    3  
 
Condensed Statements of Operations Three and six months ended June 30, 2003 and 2002
    4  
 
Condensed Statements of Cash Flows Six months ended June 30, 2003 and 2002
    5  
 
Notes to Condensed Financial Statements
    6  
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations
    8  
Item 3. Quantitative and Qualitative Disclosures About Market Risk
    12  
Item 4. Controls and Procedures
    12  
PART II. OTHER INFORMATION
       
Item 4. Submission of Matters to a Vote of Security Holders
    13  
Item 6. Exhibits and Reports on Form 8-K
    13  
SIGNATURES
    14  

 


Table of Contents

PART I — FINANCIAL INFORMATION

Item 1. Financial Statements

ATHEROGENICS, INC.

CONDENSED BALANCE SHEETS
                     
        June 30,   December 31,
        2003   2002
       
 
        (Unaudited)   (Audited)
ASSETS
               
Current assets:
               
 
Cash and cash equivalents
  $ 38,718,011     $ 32,132,329  
 
Short-term investments
    22,482,048       2,538,802  
 
Prepaid expense
    2,211,828       166,995  
 
Notes receivable and other current assets
    172,077       56,726  
 
   
     
 
   
Total current assets
    63,583,964       34,894,852  
Equipment and leasehold improvements, net of accumulated depreciation and amortization
    2,806,595       2,825,267  
Notes receivable, net of current portion
    211,809       231,925  
 
   
     
 
   
Total assets
  $ 66,602,368     $ 37,952,044  
 
   
     
 
LIABILITIES AND SHAREHOLDERS’ EQUITY
               
Current liabilities:
               
 
Accounts payable
  $ 1,979,247     $ 1,959,295  
 
Accrued research and development costs
    4,315,637       945,506  
 
Accrued liabilities
    708,413       589,345  
 
Accrued compensation
    606,762       957,056  
 
Current portion of equipment loan facility
    461,415       434,637  
 
   
     
 
   
Total current liabilities
    8,071,474       4,885,839  
Equipment loan facility, net of current portion
    327,934       572,492  
Shareholders’ equity:
               
 
Preferred stock, no par value: Authorized — 5,000,000 shares
           
 
Common stock, no par value: Authorized — 100,000,000 shares; issued and outstanding — 36,522,896 and 28,133,560 shares at June 30, 2003 and December 31, 2002, respectively
    171,273,523       122,182,607  
   
Warrants
    1,087,536       798,076  
   
Deferred stock compensation
    (1,072,843 )     (1,243,786 )
 
Accumulated deficit
    (113,074,173 )     (89,243,494 )
 
Accumulated other comprehensive (loss) income
    (11,083 )     310  
 
   
     
 
   
Total shareholders’ equity
    58,202,960       32,493,713  
 
   
     
 
   
Total liabilities and shareholders’ equity
  $ 66,602,368     $ 37,952,044  
 
   
     
 

The accompanying notes are an integral part of these condensed financial statements.

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ATHEROGENICS, INC.

CONDENSED STATEMENTS OF OPERATIONS
(Unaudited)
                                     
        Three months ended   Six months ended
        June 30,   June 30,
       
 
        2003   2002   2003   2002
       
 
 
 
Revenues
  $     $     $     $  
Operating expenses:
                               
 
Research and development
    10,833,917       5,317,582       20,992,318       10,703,196  
 
General and administrative
    1,238,980       1,024,849       2,432,272       2,008,195  
 
Amortization of deferred stock compensation
    469,517       499,323       790,186       998,646  
 
   
     
     
     
 
   
Total operating expenses
    12,542,414       6,841,754       24,214,776       13,710,037  
 
   
     
     
     
 
Operating loss
    (12,542,414 )     (6,841,754 )     (24,214,776 )     (13,710,037 )
Net interest income
    206,436       269,260       384,097       573,828  
 
   
     
     
     
 
Net loss
  $ (12,335,978 )   $ (6,572,494 )   $ (23,830,679 )   $ (13,136,209 )
 
   
     
     
     
 
Net loss per share — basic and diluted
  $ (0.34 )   $ (0.24 )   $ (0.68 )   $ (0.47 )
 
   
     
     
     
 
Weighted average shares outstanding — basic and diluted
    36,458,982       27,925,386       34,884,745       27,900,963  
 
   
     
     
     
 

The accompanying notes are an integral part of these condensed financial statements.

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ATHEROGENICS, INC.

CONDENSED STATEMENTS OF CASH FLOWS
(Unaudited)
                       
          Six months ended
          June 30,
         
          2003   2002
         
 
Operating activities:
               
Net loss
  $ (23,830,679 )   $ (13,136,209 )
Adjustments to reconcile net loss to net cash used in operating activities:
               
 
Depreciation and amortization
    398,460       359,113  
 
Amortization of deferred stock compensation
    790,186       998,646  
 
Changes in operating assets and liabilities:
               
   
Prepaid expenses
    (2,044,833 )     (20,944 )
   
Notes receivable and other current assets
    (95,235 )     (46,413 )
   
Accounts payable
    19,952       (420,051 )
   
Accrued research and development
    3,370,131       203,983  
   
Accrued liabilities
    (231,226 )     (201,694 )
 
   
     
 
     
Net cash used in operating activities
    (21,623,244 )     (12,263,569 )
Investing activities:
               
Purchases of equipment and leasehold improvements
    (379,788 )     (395,342 )
(Purchases) sales of short-term investments
    (19,954,639 )     11,625,629  
 
   
     
 
     
Net cash (used in) provided by investing activities
    (20,334,427 )     11,230,287  
Financing activities:
               
Proceeds from the issuance of common stock
    48,411,649        
Proceeds from the exercise of common stock options
    349,484       58,521  
Proceeds from equipment loan facility
          936,851  
Payments on equipment loan facility and capital lease obligation
    (217,780 )     (126,911 )
 
   
     
 
     
Net cash provided by financing activities
    48,543,353       868,461  
 
   
     
 
Increase (decrease) in cash and cash equivalents
    6,585,682       (164,821 )
Cash and cash equivalents at beginning of period
    32,132,329       28,682,050  
 
   
     
 
Cash and cash equivalents at end of period
  $ 38,718,011     $ 28,517,229  
 
   
     
 
Supplemental disclosures of cash flow information:
               
Interest paid
  $ 35,175     $ 17,255  
Remeasurement adjustment for variable options and warrants issued for technology license agreements and consulting agreements
    619,243       147,015  

The accompanying notes are an integral part of these condensed financial statements.

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ATHEROGENICS, INC.

NOTES TO CONDENSED FINANCIAL STATEMENTS
(Unaudited)

1. Basis of Presentation

     The accompanying unaudited condensed financial statements reflect all adjustments (consisting solely of normal recurring adjustments) which management considers necessary for a fair presentation of the financial position, results of operations and cash flows of AtheroGenics for the interim periods presented. Certain footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States have been condensed or omitted from the interim financial statements as permitted by the rules and regulations of the Securities and Exchange Commission. Interim results are not necessarily indicative of results for the full year.

     The interim results should be read in conjunction with the financial statements and notes thereto included in AtheroGenics’ Annual Report on Form 10-K for the year ended December 31, 2002. Shareholders are encouraged to review the Form 10-K for a broader discussion of AtheroGenics’ opportunities and risks inherent in the business. Copies of the Form 10-K are available on request.

2. Recently Issued Accounting Standards

     In December 2002, the Financial Accounting Standards Board (“FASB”) issued Statement of Financial Accounting Standards (“SFAS”) No. 148, Accounting for Stock-Based Compensation — Transition and Disclosure (“SFAS 148”), that amends SFAS No. 123, Accounting for Stock-Based Compensation (“SFAS 123”), to provide alternative methods of transition to SFAS 123’s fair value method of accounting for stock-based employee compensation. SFAS 148 also amends the disclosure provisions of SFAS 123 and APB Opinion No. 28, Interim Financial Reporting, to require disclosure in the summary of significant accounting policies of the effects of an entity’s accounting policy with respect to stock-based employee compensation on reported net income and earnings per share in annual and interim financial statements. SFAS 148 does not amend SFAS 123 to require companies to account for employee stock options using the fair value method. SFAS 148 is effective for fiscal years beginning after December 15, 2002. AtheroGenics adopted the new disclosure provisions in accordance with SFAS 148, as discussed in note 4 “Stock-Based Compensation.”

3. Net Loss per Share

     SFAS No. 128, Earnings per Share, requires presentation of both basic and diluted earnings per share. Basic earnings per share is computed by dividing net income (loss) by the weighted average number of shares of common stock outstanding during the period. Diluted earnings per share is computed in the same manner as basic earnings per share except that diluted earnings per share reflects the potential dilution that would occur if outstanding options and warrants were exercised. Because AtheroGenics reported a net loss for all periods presented, shares associated with stock options and warrants are not included because they are antidilutive. Basic and diluted net loss per share amounts are the same for the periods presented.

4. Stock-Based Compensation

     AtheroGenics has elected to follow Accounting Principles Board (“APB”) Opinion No. 25, Accounting for Stock Issued to Employees (“APB 25”), in accounting for its stock-based employee compensation plans, rather than the alternative fair value accounting method provided for under SFAS 123, as SFAS 123 requires the use of option valuation models that were not developed for use in valuing employee stock options. AtheroGenics accounts for transactions in which services are received in exchange for equity instruments based on the fair value of such services received from non-employees, in accordance with SFAS 123 and Emerging Issues Task Force (“EITF”) Issue No. 96-18, Accounting for Equity Instruments that are Issued to Other than Employees for Acquiring, or in Conjunction with Selling, Goods or Services.

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     The following table illustrates the effect on net loss and net loss per share if the fair value based method had been applied to all outstanding and unvested options in each period, based on the provisions of SFAS 123 and SFAS 148.

                   
      June 30,
     
      2003   2002
     
 
Net loss, as reported
  $ (23,830,679 )   $ (13,136,209 )
Add: Stock-based employee compensation expense included in reported net loss
    281,560       784,020  
Deduct: Total stock-based employee compensation expense determined under fair value based method for all awards
    (1,723,627 )     (1,683,509 )
 
   
     
 
Pro forma net loss
  $ (25,272,746 )   $ (14,035,698 )
 
   
     
 
Net loss per share:
               
 
Basic and diluted, as reported
  $ (0.68 )   $ (0.47 )
 
   
     
 
 
Basic and diluted, pro forma
  $ (0.72 )   $ (0.50 )
 
   
     
 

5. Deferred Stock Compensation

     Deferred compensation for options granted to employees represents the difference between the exercise price and the deemed fair value of AtheroGenics’ common stock on the dates these stock options were granted. The deferred compensation is included as a reduction of shareholders’ equity and is amortized over the vesting periods of the individual options, generally four years, using the graded vesting method. The graded vesting method provides for vesting of portions of the overall award at interim dates and results in higher vesting in earlier years than straight-line vesting.

     Deferred compensation for options and warrants granted to consultants is determined in accordance with SFAS 123 and EITF Issue No. 96-18 as the fair value of the equity instruments issued. Deferred compensation for options and warrants granted to consultants is adjusted to fair market value on each balance sheet date.

     At June 30, 2003, AtheroGenics had a total of $1,072,843 remaining to be amortized over the vesting periods of all stock options and warrants.

6. Follow-on Offering

     In February 2003, AtheroGenics completed a follow-on public offering of 8,280,000 shares of common stock (including the exercise of the underwriters’ over-allotment option) that raised net proceeds of approximately $48,400,000.

7. Bank Credit Agreements

     In March 2002, AtheroGenics entered into a revolving credit facility with Silicon Valley Bank for up to a maximum amount of $5,000,000 to be used for working capital requirements. Under the terms of the facility, interest on advances is charged at the Bank’s prime rate plus 1.50% per year, provided that certain liquidity levels are maintained; otherwise interest will be charged at prime rate plus 2.0% per year. Amounts borrowed under the revolving credit facility may be repaid and reborrowed at any time and from time to time during the term of the facility. The revolving line of credit terminates on September 5, 2004 and all outstanding amounts and accrued interest will be due and payable on that date. As of June 30, 2003, there were no outstanding balances under the revolving credit facility.

     In addition, in March 2002, AtheroGenics entered into an equipment loan facility with Silicon Valley Bank for up to a maximum amount of $2,500,000 to be used to finance existing and new equipment purchases. The interest rate on the equipment advances was equal to the greater of (1) the Bank’s prime rate plus 3.0% or (2) 7.5% per year and was fixed at the time of each advance. Amounts borrowed under the equipment loan facility are repaid in 33 equal installments of principal and interest beginning on the first business day of the month following an

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advance. As of June 30, 2003, there was an outstanding balance of $789,349 under the equipment loan facility and the weighted average interest rate was 7.7%.

     As collateral for the revolving credit facility and for the equipment loan facility, AtheroGenics granted to Silicon Valley Bank a security interest in all of its assets other than its intellectual property, and granted a negative pledge on its intellectual property. Also, in conjunction with these facilities, AtheroGenics was required to maintain a $15 million compensating cash balance in an account with the Bank.

     In June 2003, AtheroGenics entered into a loan modification agreement related to the equipment loan facility extending the borrowing period until September 30, 2003 and canceling the compensating cash balance requirement on the revolving credit facility and the equipment loan facility.

8. Reclassifications

     Certain prior year balances have been reclassified to conform with the current year presentation. These reclassifications had no effect on previously reported net loss or shareholders’ equity.

9. Subsequent Events

     On August 12, 2003, we announced an offer to issue $75.0 million of convertible notes due 2008 through a Rule 144A offering to qualified institutional buyers. These notes will be convertible into AtheroGenics, Inc. common stock at a price to be determined.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations

     The following should be read with the financial statements and related footnotes and Management’s Discussion and Analysis of Financial Condition and Results of Operations included in AtheroGenics’ Annual Report on Form 10-K for the fiscal year ended December 31, 2002. The results discussed below are not necessarily indicative of the results to be expected in any future periods. The following discussion contains forward-looking statements that are subject to risks and uncertainties which could cause actual results to differ from the statements made. These risks are set forth in more detail in our Annual Report on Form 10-K.

OVERVIEW

     Since our operations began in 1994, we have focused on the discovery, development and commercialization of novel drugs for the treatment of chronic inflammatory diseases, including heart disease (atherosclerosis), rheumatoid arthritis, organ transplant rejection and asthma. Based on our proprietary vascular protectant, or v-protectant™, technology platform, we have four drug programs in the clinic, and are pursuing a number of other preclinical programs.

     AGI-1067 is our v-protectant candidate that is most advanced in clinical development, and is designed to benefit patients with heart disease. AGI-1067 is currently in a Phase III clinical trial, referred to as ARISE, or Aggressive Reduction of Inflammation Stops Events, to evaluate the impact of AGI-1067 on important outcome measures such as death due to heart disease, myocardial infarction, stroke, coronary revascularization and unstable angina in patients who have coronary heart disease. ARISE will enroll 4,000 patients who will be followed for an average of 18 months or until a minimum of 1,160 primary events, or outcome measures, have occurred. We recently completed enrollment in our AGI-1067 CART-2 Phase IIb clinical trial. CART-2 is a 12-month, 500 patient, double-blind, placebo-controlled trial of AGI-1067 280mg, administered orally once daily, versus placebo, to assess the effect of AGI-1067 on the progression of atherosclerosis in patients with heart disease. We expect to complete the treatment phase of CART-2 in 12 months and will then proceed with data analysis and disclosure of the results.

     Our second clinical compound, AGIX-4207, is a novel oral agent being developed for the treatment of the signs and symptoms of rheumatoid arthritis. We have completed a Phase II clinical trial that evaluated safety, tolerability and the effect of orally administered AGIX-4207 on biological markers of inflammation in rheumatoid arthritis patients. Data from the trial demonstrated that treatment with AGIX-4207 was safe and well tolerated by patients and also inhibited an increase in the inflammatory biomarker know as the erythrocyte sedimentation rate, or ESR, by more than 90 percent. Planning is underway for a 220 patient Phase II trial of AGIX-4207, called OSCAR,

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or Oral Suppression of Cellular Inflammation Attenuates Rheumatoid Arthritis, which is scheduled to begin later this year. OSCAR will evaluate the impact of various doses of AGIX-4207 versus placebo on clinical efficacy, biomarkers and safety in patients with mild to moderate rheumatoid arthritis. AGIX-4207 I.V., our third v-protectant candidate, is an intravenous drug designed to treat rheumatoid arthritis patients in whom the rapid attainment of target drug levels in the blood is desirable. We have completed a Phase I clinical trial that assessed the safety and tolerability of AGIX-4207 I.V. in healthy volunteers. The results from this trial demonstrated that single infusions of AGIX-4207 I.V. were well tolerated and adverse events were generally mild and not considered clinically significant.

     Our fourth v-protectant drug, AGI-1096, is a novel antioxidant and selective anti-inflammatory agent that is being developed to address the accelerated inflammation of grafted blood vessels, known as transplant arteritis, common in chronic organ transplant rejection. We have completed a Phase I clinical trial that assessed safety and tolerability of AGI-1096 in healthy volunteers. The results of AGI-1096 clinical trial data demonstrated the drug was well tolerated at all oral doses, with no drug-related adverse events.

     To date, we have devoted substantially all of our resources to research and development. We have not received any commercial revenues from product sales. We expect to incur significant losses in most years prior to deriving any product revenue as we continue to increase research and development costs. We have incurred significant losses since we began operations in 1994 and as of June 30, 2003, we had an accumulated deficit of $113.1 million. We cannot assure you that we will become profitable. We expect that losses will fluctuate from quarter to quarter and that these fluctuations may be substantial. Our ability to achieve profitability depends upon a variety of factors, including our ability, alone or with others, to complete the successful development of our product candidates, to obtain required regulatory clearances, and to manufacture and market our future products.

     On August 12, 2003, we announced an offer to issue $75.0 million of convertible notes due 2008 through a Rule 144A offering to qualified institutional buyers. These notes will be convertible into our common stock at a price to be determined.

RESULTS OF OPERATIONS

Comparison of the Three and Six Month Periods Ended June 30, 2003 and 2002

Revenues

     There were no revenues during the three and six months ended June 30, 2003 and 2002.

Expenses

     Research and Development. Research and development expenses increased 104% to $10.8 million for the three months ended June 30, 2003 from $5.3 million for the comparable period in 2002, and 96% to $21.0 million for the six months ended June 30, 2003 from $10.7 million in the comparable period in 2002. The increase in research and development expenses for the three and six months ended June 30, 2003 was primarily due to start-up expenditures related to the AGI-1067 ARISE Phase III clinical trial, such as manufacturing activities for clinical drug supply, clinical site selection and investigator recruitment. In addition, there were increased expenditures for the ongoing AGI-1067 CART-2 Phase IIb clinical trial.

     General and Administrative. General and administrative expenses increased 21% to $1.2 million for the three months ended June 30, 2003 from $1.0 million for the comparable period in 2002, and 21% to $2.4 million for the six months ended June 30, 2003 from $2.0 million in the comparable period in 2002. The increase in general and administrative expenses for the three and six months ended June 30, 2003 was primarily due to business development activities, including increased staffing and partnership discussions for AGI-1067.

     Amortization of Deferred Stock Compensation. Amortization of deferred stock compensation was $469,517 for the three months ended June 30, 2003, compared to $499,323 for the comparable period in 2002, and $790,186 for the six months ended June 30, 2003, compared to $998,646 for the comparable period in 2002. The decrease in the three and six months ended June 30, 2003 is due to the deferred stock compensation being amortized using the graded vesting method, which results in higher amortization in the earlier years. The decrease was partially offset by the effect of remeasuring options and warrants granted to consultants to current fair market value.

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Net Interest Income

     Net interest income decreased 23% from $269,260 for the three months ended June 30, 2002 to $206,436 for the comparable period in 2003. Net interest income decreased 33% from $573,828 for the six months ended June 30, 2002 to $384,097 for the comparable period in 2003. The decrease in net interest income is a reflection of lower average interest rates.

LIQUIDITY AND CAPITAL RESOURCES

     Since inception, we have financed our operations primarily through sales of equity securities, borrowings and payments received from a license agreement, which was subsequently terminated. At June 30, 2003, we had cash, cash equivalents and short-term investments of $61.2 million, compared with $34.7 million at December 31, 2002. Working capital at June 30, 2003 was $55.5 million, compared to $30.0 million at December 31, 2002. The increase in cash, cash equivalents, short-term investments and working capital is primarily due to a follow-on public offering of 8.3 million shares of common stock (including the exercise of the underwriters’ over-allotment option) in the first quarter of 2003 that raised net proceeds of approximately $48.4 million.

     Net cash used in operating activities was $21.6 million for the six months ended June 30, 2003, compared to $12.3 million for the comparable period in 2002. The increase in the use of cash in operating activities is principally due to funding a net loss of $23.8 million and an increase in prepaid expense of $2.0 million. The increase in cash to fund the net loss is primarily attributable to the expenditures for the initiation of our ARISE Phase III clinical trial and the continuation of our CART-2 Phase IIb clinical trial for AGI-1067 as well as other ongoing product development activities. The increase in prepaid expense is due pre-commencement payments to contractors for the ARISE clinical trial. In connection with entering into the ARISE clinical trial for AGI-1067 and the resultant increase in cash usage, we expect that prepaid expenses and the research and development accrual may fluctuate more significantly than in previous periods. We anticipate net cash usage in 2003 for the ARISE clinical trial, in combination with our other operating activities and on-going clinical programs, to be approximately $48.0 million.

     Net cash used in investing activities was $20.3 million for the six months ended June 30, 2003, compared to $11.2 million provided by investing activities for the comparable period in 2002. Net cash used in investing activities during the six months ended June 30, 2003 consisted primarily of the purchases of available-for-sale securities and equipment and leasehold improvements. Net cash provided by investing activities during the six months ended June 30, 2002 consisted primarily of the sales of available-for-sale securities, with the proceeds reinvested in interest bearing cash equivalents, partially offset by the purchase of equipment and leasehold improvements.

     Net cash provided by financing activities was $48.5 million for the six months ended June 30, 2003, and $868,461 for the comparable period in 2002. Net cash provided by financing activities in the six months ended June 30, 2003 consisted primarily of proceeds of approximately $48.4 million from the follow-on public offering of 8.3 million shares of our common stock. This was partially offset by payments on our equipment loan facility. Net cash provided by financing activities in the six months ended June 30, 2002 consisted of the receipt of funds from the equipment loan facility and exercise of stock options, offset by payments for capital lease obligations.

     In March 2002, we entered into a revolving credit facility with Silicon Valley Bank in the amount of up to $5.0 million to be used for working capital requirements. In addition, we entered into an equipment loan facility with Silicon Valley Bank in the amount of up to $2.5 million to be used to finance existing and new equipment purchases. At June 30, 2003 there was no outstanding balance on the revolving credit facility and an outstanding balance of $789,349 with a weighted average interest rate of 7.7% on the equipment loan facility. As collateral for the revolving credit facility and for the equipment loan facility, AtheroGenics granted to Silicon Valley Bank a security interest in all of its assets other than its intellectual property, and granted a negative pledge on its intellectual property. Also, in conjunction with these facilities, AtheroGenics was required to maintain a $15 million compensating cash balance in an account with the Bank.

     In June 2003, AtheroGenics entered into a loan modification agreement related to the equipment loan facility extending the borrowing period until September 30, 2003 and canceling the compensating cash balance requirement on the revolving credit facility and the equipment loan facility.

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     On August 12, 2003, we announced an offer to issue $75.0 million of convertible notes due 2008 through a Rule 144A offering to qualified institutional buyers. These notes will be convertible into our common stock at a price to be determined.

     The following table summarizes our long-term contractual obligations as of June 30, 2003.

                                 
    2003   2004-2005   2006-2007   Thereafter
   
 
 
 
Operating leases, net of sublease income
  $ 529,470     $ 2,086,674     $ 2,273,790     $ 1,326,378  
Long-term debt
    216,857       572,492              
 
   
     
     
     
 
Total contractual obligations
  $ 746,327     $ 2,659,166     $ 2,273,790     $ 1,326,378  
 
   
     
     
     
 

     Based upon the current status of our product development and commercialization plans, we believe that our existing cash and cash equivalents and short-term investments, along with our revolving credit facility with Silicon Valley Bank and the expected proceeds from the recent offer to issue convertible notes, will be adequate to satisfy our capital needs for at least the next 12 months. However, our actual capital requirements will depend on many factors, including:

    the status of product development;
 
    the time and cost involved in conducting clinical trials and obtaining regulatory approvals;
 
    the costs of filing, prosecuting and enforcing patent and other intellectual property claims;
 
    competing technological and market developments; and
 
    our ability to establish new licensing agreements.

FORWARD-LOOKING STATEMENTS

     The Private Securities Litigation Reform Act of 1995 (the “Reform Act”) provides a safe harbor for forward-looking statements made by or on behalf of AtheroGenics. AtheroGenics and its representatives may from time to time make written or oral forward-looking statements, including statements contained in this report and our other filings with the Securities and Exchange Commission and in our reports to our shareholders. Generally, the words “believe,” “expect,” “intend,” “estimate,” “anticipate,” “will” and similar expressions identify forward-looking statements. All statements which address operating performance, events or developments that we expect or anticipate will occur in the future, such as projections about our future results of operations or our financial condition, research, development and commercialization of our product candidates and anticipated trends in our business, are forward-looking statements within the meaning of the Reform Act. The forward-looking statements are and will be based on management’s then current views and assumptions regarding future events and operating performance, and speak only as of their dates. AtheroGenics undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

     The following are some of the factors that could affect our financial performance or could cause actual results to differ materially from those expressed or implied in our forward-looking statements:

    AGI-1067, AGIX-4207, AGIX-4207 I.V. and AGI-1096 may fail in clinical trials;
 
    our ability to generate positive cash flow in light of our history of operating losses;
 
    our inability to obtain additional financing on satisfactory terms, which could preclude us from developing or marketing our products;
 
    our ability to successfully develop our other product candidates;
 
    our ability to commercialize our product candidates if we fail to demonstrate adequately their safety and efficacy;

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    possible delays in our clinical trials;
 
    our inability to predict whether or when we will obtain regulatory approval to commercialize our product candidates or the timing of any future revenue from these product candidates;
 
    our need to comply with applicable regulatory requirements in the manufacture and distribution of our products to avoid incurring penalties that may inhibit our ability to commercialize our products;
 
    our ability to protect adequately or enforce our intellectual property rights or secure rights to third party patents;
 
    the ability of our competitors to develop and market anti-inflammatory products that are more effective, have fewer side effects or are less expensive than our current or future product candidates;
 
    third parties’ failure to synthesize and manufacture our product candidates, which could delay our clinical trials or hinder our commercialization prospects;
 
    our ability to create sales, marketing and distribution capabilities or enter into agreements with third parties to perform these functions;
 
    our ability to attract, retain and motivate skilled personnel and cultivate key academic collaborations;
 
    our ability to obtain an adequate level of reimbursement or acceptable prices for our products; and
 
    if plaintiffs bring product liability lawsuits against us, we may incur substantial financial loss or may be unable to obtain future product liability insurance at reasonable prices, if at all, either of which could diminish our ability to commercialize our future products.

     The foregoing list of important factors is discussed in more detail in our Annual Report on Form 10-K for the fiscal year ended December 31, 2002 and is not exclusive.

Item 3. Quantitative And Qualitative Disclosures About Market Risk

     Market risk represents the risk of loss that may impact our financial position, operating results or cash flows due to changes in U.S. interest rates. This exposure is directly related to our normal operating activities. Our cash, cash equivalents and short-term investments are invested with high quality issuers and are generally of a short-term nature. Interest rates payable on our lease obligations are generally fixed. As a result, we do not believe that near-term changes in interest rates will have a material effect on our future results of operations.

     The following table summarizes information on our equipment loan facility. The table presents maturity of the debt and projected annual average interest rates as of June 30, 2003.

                                           
                                      Value as of
      2003   2004   2005   Total   June 30, 2003
     
 
 
 
 
Long-term debt — fixed rate
                                       
 
Maturity
  $ 216,857     $ 488,870     $ 83,622     $ 789,349     $ 789,349  
 
Average interest rate
    7.7 %     7.7 %     7.7 %                

Item 4. Controls and Procedures

     Evaluation of disclosure controls and procedures. Our chief executive officer and chief financial officer are responsible for establishing and maintaining “disclosure controls and procedures” (as defined in the Securities Exchange Act of 1934 Rules 13a-15(e) and 15d-15(e)) for AtheroGenics. Our chief executive officer and chief financial officer, after evaluating the effectiveness of our disclosure controls and procedures as of the end of the period covered by this quarterly report, have concluded that our disclosure controls and procedures are adequate and effective in timely alerting them to material information relating to us required to be included in our periodic SEC filings.

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     Changes in internal control over financial reporting. There were no material changes in our internal control over financial reporting that occurred during our most recent fiscal quarter that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

PART II — OTHER INFORMATION

Item 4. Submission of Matters to a Vote of Security Holders

     Our annual meeting of shareholders was held on May 8, 2003. At the annual meeting, the shareholders of AtheroGenics (1) elected three Class III directors to serve until the 2006 Annual Meeting of Shareholders and (2) ratified the appointment of Ernst & Young LLP as our independent auditors for the fiscal year ending December 31, 2003.

     We had 36,426,960 shares of common stock outstanding as of March 3, 2003, the record date of the annual meeting. At the annual meeting, we had 29,552,915 share of common stock present in person or represented by proxy for the two proposals indicated above. The following sets forth detailed information regarding the results of the voting at the annual meeting:

Proposal 1. Election of three Class II directors

                 
Name of Nominee   No. of Votes For   No. of Votes Withheld

 
 
Michael A. Henos
    27,123,672       2,429,243  
Russell M. Medford
    27,911,208       1,641,707  
Arthur M. Pappas
    28,779,103       773,812  

Proposal 2. Ratifications of the appointment of independent auditors

                 
No. of Votes For   No. of Votes Against   Abstention

 
 
29,367,363
    181,500       4,052  

Item 6. Exhibits and Reports on Form 8-K

(a)  Exhibits

         
Exhibit 10.23     First Loan Modification dated June 20, 2003 between AtheroGenics, Inc. and Silicon Valley Bank.
Exhibit 31     Certifications of Chief Executive Officer and Chief Financial Officer under Rule 13a-14(a).
Exhibit 32     Certifications of Chief Executive Officer and Chief Financial Officer under Section 1350.

(b)  Reports on Form 8-K

     On April 23, 2003, we furnished a Current Report on Form 8-K under Item 12, reporting the issuance of our press release announcing our financial results for the first quarter ended March 31, 2003.

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SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

     
    ATHEROGENICS, INC
     
Date: August 13, 2003   /s/ MARK P. COLONNESE
   
    Mark P. Colonnese
Senior Vice President of Finance and Administration and Chief Financial Officer

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