SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 AMENDMENT ONE FOR PERMA-FIX ENVIRONMENT SERVICES INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 7141571049 (CUSIP Number) 17/03/2006 (Date of Event Which Requires Filing of this Statement) Check appropriate box to designate the rule pursuant to which this Schedule is filed: [ ] Rule 13d-1(b) [X] Rule 13d-1(c) [ ] Rule 13d-1(d) -------------------- ----------------- CUSIP No. 7141571049 13G Page 1 of 1 Pages -------------------- ----------------- -------------------------------------------------------------------------------- 1 Names of Reporting Persons/I.R.S. Identification Nos. of Above Persons (Entities Only) Pictet (London) Limited Pictet Asset Management Limited ("PAM") Pictet (London) Limited is the parent corporation of PAM The reporting persons disclaim beneficial ownership of the shares reported, which are owned of record and beneficially by two non-U.S. investment funds, both managed by PAM. -------------------------------------------------------------------------------- 2 Check the Appropriate Box if a Member of a Group (a) [ ] (b) [ ] -------------------------------------------------------------------------------- 3 SEC Use Only -------------------------------------------------------------------------------- 4 Citizenship or Place of Organization Pictet (London) Limited - United Kingdom Pictet Asset Management Limited - United Kingdom -------------------------------------------------------------------------------- 5 Sole Voting Power: Pictet (London) Limited: 4,199,160 (indirect through PAM) PAM: 4,199,160 ----------------------------------------------------------------- Number of 6 Shared Voting Power: Shares Pictet (London) Limited: None Beneficially PAM: None Owned by ----------------------------------------------------------------- Each 7 Sole Dispositive Power: Reporting Pictet (London) Limited: 4,199,160 Person With (indirect through PAM) PAM: 4,199,160 ----------------------------------------------------------------- 8 Shared Dispositive Power: Pictet (London) Limited: None PAM: None -------------------------------------------------------------------------------- 9 Aggregate Amount Beneficially Owned by Each Reporting Person Pictet (London) Limited: 4,199,160 (indirect through PAM) PAM: 4,199,160 -------------------------------------------------------------------------------- 10 Check if the Aggregate Amount in Row (9) Excludes Certain Shares [ ] -------------------------------------------------------------------------------- 11 Percent of Class Represented by Amount in Row (9) Pictet (London) Limited: 10.01% (indirect through PAM) PAM: 10.01% -------------------------------------------------------------------------------- 12 Type of Reporting Person: Pictet (London) Limited: HC PAM: IA -------------------------------------------------------------------------------- Item 1. (a) Name of Issuer: PERMA-FIX ENVIRONMENT (b) Address of Issuer's Principal Executive Offices: 1940 Northwest 67th Place Gainesville Florida 32653 United States Item 2 (a) Names of Persons Filing: Pictet (London) Limited, holding company for: Pictet Asset Management Limited ("PAM") Pictet (London) Limited is the parent corporation of PAM (b) Address of Principal Business Office or, if none, Residence: Pictet (London) Limited: Tower 42 Level 37 25 Old Broad Street London EC2N 1HQ UNITED KINGDOM PAM: Same (c) Citizenship: Pictet (London) Limited: United Kingdom PAM: Same (d) Title of Class Securities: Common Stock (e) CUSIP Number: 7141571049 Item 3. If this statement is filed pursuant to Rule 13d-1 (b), or 13d-2 (b) or (c), check whether the person is A Not applicable. Item 4. Ownership The reporting persons disclaim beneficial ownership of the shares reported, which are owned of record and beneficially by two non-U.S. investment funds, both are managed by PAM. (a) Amount Beneficially Owned: Pictet (London) Limited: 4,199,160 (indirect through PAM) PAM: 4,199,160 (b) Percent of Class: Pictet (London) Limited: 10.01% (indirect through PAM) PAM: 10.01% (c) Number of shares as to which such person has: Pictet (London) Limited (indirectly through PAM): (i) sole power to vote or to direct the vote: 4,199,160 (ii) shared power to vote or to direct the vote: None (iii) sole power to dispose or to direct the disposition of: 4,199,160 (iv) shared power to dispose or to direct the disposition of: None PAM: (i) sole power to vote or to direct the vote: 4,199,160 (ii) shared power to vote or to direct the vote: None (iii) sole power to dispose or to direct the disposition of: 4,199,160 (iv) shared power to dispose or to direct the disposition of: None Item 5. Ownership of Five Percent or Less of a Class Not applicable. Item 6. Ownership of More than Five Percent on Behalf of Another Person Not applicable. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company See answer to Item 2 (a) Item 8. Identification and Classification of Members of the Group Not applicable. Item 9. Notice of Dissolution of the Group Not applicable. Item 10. Certification By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect. SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Date: 2 April, 2006 ---------------------------------- /s/ David Cawthrow ---------------------------------------- David Cawthrow Chief Compliance Officer AGREEMENT OF REPORTING PERSONS The undersigned herby agree that the foregoing Schedule 13G is filed on behalf of each of the undersigned. Pictet (London) Limited Pictet Asset Management Limited By: /s/ David Cawthrow By: /s/ David Cawthrow --------------------------------- ------------------------------------ David Cawthrow, Chief Compliance David Cawthrow, Chief Compliance Officer Officer