Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
KLEINHEINZ CAPITAL PARTNERS, INC.
  2. Issuer Name and Ticker or Trading Symbol
InfuSystem Holdings, Inc [INHI.OB]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
301 COMMERCE STREET, SUITE 1900
3. Date of Earliest Transaction (Month/Day/Year)
02/25/2010
(Street)

FORT WORTH, TX 76102
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, par value $0.0001 per share 02/25/2010   P   500,000 A $ 2.4 2,072,480 (1) I See Footnote (2)
Common Stock, par value $0.0001 per share 02/25/2010   S   5,000 D $ 2.23 2,067,480 (1) I See Footnote (2)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
KLEINHEINZ CAPITAL PARTNERS, INC.
301 COMMERCE STREET
SUITE 1900
FORT WORTH, TX 76102
    X    
Kleinheinz Capital Partners LDC
C/O WALKERS SPV LIMITED
WALKER HOUSE, 87 MARY STREET
GEORGE TOWN, GRAND CAYMAN, E9 KYI-9002
    X    
KLEINHEINZ JOHN B
301 COMMERCE STREET
SUITE 1900
FORT WORTH, TX 76102
    X    

Signatures

 /s/ John Kleinheinz, Director of Kleinheinz Capital Partners, Inc.   03/01/2010
**Signature of Reporting Person Date

 /s/ John Kleinheinz, Managing Director of Kleinheinz Capital Partners, LDC   03/01/2010
**Signature of Reporting Person Date

 /s/ John Kleinheinz   03/01/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The filing of this Form 4 shall not be construed as an admission that Kleinheinz Capital Partners, Inc., Kleinheinz Capital Partners LDC or John Kleinheinz is or was for the purpose of Section 16(a) of the Securties Exchange Act of 1934, as amended, or otherwise a beneficial owner of any of the shares of common stock, par value $0.0001 per share ("Common Stock") of Infusystem Holdings, Inc. held and owned by Global Undervalued Securities Master Fund, LP. (and by Global Undervalued Securities Fund, LP, Global Undervalued Securities Fund (QP), LP, and Global Undervalued Securities Fund, Ltd., each of which serves as a general partner to, and a feeder fund of, Global Undervalued Securities Master Fund, LP). Pursuant to Rule 16a-1, each of Kleinheinz Capital Partners, Inc., Kleinheinz Capital Partners LDC and John Kleinheinz disclaims such beneficial ownership.
(2) Kleinheinz Capital Partners LDC holds indirectly shares of Common Stock on behalf of Global Undervalued Securities Fund, LP, and Global Undervalued Securities Fund (QP), LP for which Kleinheinz Capital Partners LDC serves as general partner. Kleinheinz Capital Partners, Inc. holds indirectly shares of Common Stock on behalf of Global Undervalued Securities Fund, LP, Global Undervalued Securities Fund (QP), LP, Global Undervalued Securitites Fund, Ltd. and Global Undervalued Securities Master Fund, LP, for which Kleinheinz Capital Partners, Inc. serves as investment manager. John Kleinheinz report the shares of Common Stock held indirectly by Kleinheinz Capital Partners LDC and Kleinheinz Capital Partners, Inc. because, as managing director and director, respectively, at the time of purchase, he controlled the voting and disposition of the securitites.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.