FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * QUEST DIAGNOSTICS INC   2. Issuer Name and Ticker or Trading Symbol VERMILLION, INC. [VRML] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director __X__ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 1290 WALL STREET WEST 3. Date of Earliest Transaction (Month/Day/Year) 08/24/2007 (Street) LYNDHURST, NJ 07071 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 08/24/2007   A   2,380,952 A $ 0.74 8,605,952 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Warrant to Purchase (1)

$ 3.5

08/24/2007

D

2,200,000

07/22/2005

07/22/2010

Common Stock

2,200,000

$ 0

0

D

Warrant to Purchase (2)

$ 2.5

08/24/2007

A

2,200,000

08/24/2007

07/22/2011

Common Stock

2,200,000

$ 0

2,200,000

D

Warrant to Purchase

$ 0.925

08/24/2007

A

1,904,761

08/29/2007

08/29/2012

Common Stock

1,904,761

$ 0.125

1,904,761

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
QUEST DIAGNOSTICS INC 1290 WALL STREET WEST LYNDHURST, NJ 07071		X

Signatures

Leo C. Farrenkopf, Jr., VP, Quest Diagnostics		08/28/2007
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	This warrant, previously reported on Form 3 filed by Reporting Person on 7/29/2005, is being amended to reduce the exercise price from $3.50 to $2.50 and to extend the expiration date from 7/22/2010 to 7/22/2011. For SEC reporting purposes, it is being reported herein as a "disposition" of the original warrant and an "acquisition" of the warrant referred to in footnote (2) below. The amendment of the warrant is conditioned on the closing of the purchase reported in Table I, which is scheduled for 8/29/2007.
(2)	This warrant, reported herein as an "acquisition," is in fact an amendment of a warrant originally reported to the SEC on Form 3 on 7/29/2005. See also footnote (1) above.

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