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Why Pfizer (PFE) Shares Are Sliding Today

By: StockStory
November 14, 2025 at 11:36 AM EST

PFE Cover Image

What Happened?

Shares of global pharmaceutical company Pfizer (NYSE: PFE) fell 2.5% in the morning session after the company cut its stake in its pandemic partner BioNTech by more than half, a move that overshadowed other company developments. 

According to a regulatory filing, Pfizer reduced its ownership in the German firm by 54.7%, leaving it with about 1.66 million American Depositary Shares. This decision was viewed as a strategic shift by the company to make up for declining sales of pandemic-related products. The news overshadowed the completion of Pfizer's acquisition of Metsera, a deal that brought multiple obesity and cardiometabolic drug candidates into its pipeline. However, the Metsera transaction was expected to be dilutive through 2030, which likely added to investor concerns.

The stock market overreacts to news, and big price drops can present good opportunities to buy high-quality stocks. Is now the time to buy Pfizer? Access our full analysis report here.

What Is The Market Telling Us

Pfizer’s shares are not very volatile and have only had 4 moves greater than 5% over the last year. In that context, today’s move indicates the market considers this news meaningful, although it might not be something that would fundamentally change its perception of the business.

The previous big move we wrote about was 3 days ago when the stock gained 4.1% on the news that the market experienced a sharp sector rotation, as investors fled growth-oriented technology stocks and piled into value-oriented names amid growing valuation concerns. This divergence was stark: the tech-heavy Nasdaq struggled, losing 0.2%, while the Dow rallied. This shift away from tech was triggered by a series of negative catalysts in the AI sector. AI cloud provider CoreWeave slid on disappointing guidance, while chip darling Nvidia pulled back after SoftBank sold its stake. This "hurt the AI trade," dragging down related names like Micron and Oracle. As capital left tech, it sought safety in "higher quality" defensive names. Health care giants like Merck, Amgen, and Johnson & Johnson saw significant buying, boosting the Dow.

Pfizer is down 5.1% since the beginning of the year, but at $25.25 per share, it is still trading close to its 52-week high of $27.37 from October 2025. Investors who bought $1,000 worth of Pfizer’s shares 5 years ago would now be looking at an investment worth $676.29.

While Wall Street chases Nvidia at all-time highs, an under-the-radar semiconductor supplier is dominating a critical AI component these giants can’t build without. Click here to access our full research report.

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