Crude oil prices rebounded but the markets closed lower with the Dow losing 57 points to 17,675 as British voters prepared for the Brexit referendum next week. Nasdaq tumbled 44 points to 4,800.
On the upside
Speculation that GlobeImmune (Nasdaq: GBIM) may be an acquisition target sent shares of the biopharmaceutical soaring.
Rising crude oil prices lifted shares of SM Energy (NYSE: SM).
Citizens Community Bancorp (Nasdaq: CZWI) retained the services of FIG Partners to explore strategic opportunities.
On the downside
Beijing ordered Apple (Nasdaq: AAPL) to halt sales of its iPhone 6 and iPhone 6 Plus.
Shares of Prothena (Nasdaq: PRTA) fell again.
Profit taking weighed down shares of Eleven Biotherapeutics (Nasdaq: EBIO).
In the broad market, advancing issues outpaced decliners by a margin of more than 3 to 2 on the NYSE while decliners edged out advancers by more than 9 to 7 on Nasdaq. The broader S&P 500 lost 6 points to 2,071. Bitcoin tumbled $17 to $736.