REGULATED INFORMATION

Publication relating to transparency notifications

Mont-Saint-Guibert (Belgium), May 30, 2025, 10:30 pm CET / 4:30 pm ET – In accordance with article 14 of the Act of 2 May 2007 on the disclosure of large shareholdings, Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) announces that it received a transparency notification as detailed below.

Vestal Point Capital

On May 27, 2025, Nyxoah received a transparency notification from Vestal Point Capital following an acquisition or disposal of voting securities or voting rights. Based on the notification, Vestal Point Capital holds 1,809,843 voting rights, representing 4.84% of the total number of voting rights on May 21, 2025 (37,427,265).

The notification dated May 27, 2025 contains the following information:

• Reason for the notification: acquisition or disposal of voting securities or voting rights
• Notification by: a parent undertaking or a controlling person
• Persons subject to the notification requirement:
  • Vestal Point Capital, LLC (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
  • Vestal Point Capital, LP (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
  • Ryan Wilder (with address at 632 Broadway, Suite 602, New York, NY 10012, USA)
• Date on which the threshold was crossed: May 21, 2025
• Threshold that is crossed: 5%
• Denominator: 37,427,265
• Notified details:

• Full chain of controlled undertakings through which the holding is effectively held: Vestal Point Capital, LP (investment manager) is controlled by Vestal Point Capital, LLC (general partner). Vestal Point Capital, LLC is controlled by Mr. Ryan Wilder (managing member).
• Additional information: Vestal Point Capital, LP is the investment management company that can exercise the voting rights at its discretion, in the absence of specific instruction.

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Contact:
Nyxoah
John Landry, CFO
IR@nyxoah.com

Attachment

• 2025 05 30 PR Transparency notifications 2025 05 (Vestal Point) (ENG)