As market volatility continues, small-cap stocks are attracting investor attention with groundbreaking technological advancements, biotech breakthroughs, and resource expansion projects. Companies across multiple industries are making major strides, positioning themselves for growth and long-term value creation. Here are some of the most compelling penny stocks that are making headlines

Sharps Technology (NASDAQ: STSS), is advancing its SecureGard and SoloGard agreements following a $20 million capital raise that eliminated its debt and enhanced manufacturing operations in Hungary. The company is executing a five-year deal with a U.S. medical products firm to supply 500 million SoloGard syringes, expected to generate $50 million in revenue. Sharps remains focused on strategic growth, operational efficiency, and accelerating shipments under its existing agreements, positioning itself for strong revenue generation in late 2025.

Aditxt, Inc. (NASDAQ: ADTX) announced that its subsidiary, Adimune, Inc., is preparing to ship drug substances for the final formulation of ADI-100, a next-generation immune modulation therapy targeting Type 1 Diabetes (T1D), Psoriasis, and Stiff Person Syndrome. With all preclinical studies completed, data suggests ADI-100 restores immune tolerance without compromising immune system function. Clinical trials are set to launch in Germany and at Mayo Clinic in the U.S., marking a major step forward in autoimmune disease treatment. Aditxt remains focused on regulatory approvals and commercialization strategies to bring ADI-100 to market.

CS Diagnostics Corp. (OTCQB: CSDX) is advancing healthcare technology with the launch of CS Protect-Hydrogel, a next-generation tissue spacer for radiation therapy, designed to enhance treatment precision and patient safety. Additionally, the company introduced MEDUSA, a smart disinfectant providing long-lasting 10-day surface protection, addressing hospital-acquired infections and contamination risks. With regulatory approvals underway, CS Diagnostics is positioning itself as a key player in medical innovation, expanding market opportunities in oncology and infection prevention.

SciSparc Ltd. (NASDAQ: SPRC) and Clearmind Medicine Inc. (NASDAQ: CMND) have announced the publication of a patent application by the South Korean Intellectual Property Office (KIPO) for their psychedelic-based cocaine addiction treatment. The patent covers a novel combination therapy using Clearmind’s MEAI and SciSparc’s PEA, developed from preclinical studies demonstrating significant reductions in cocaine-induced cravings without affecting natural reward responses. This milestone builds on global patent filings, reinforcing the companies' leadership in psychedelic-assisted addiction therapies. SciSparc continues expanding its cannabinoid-based pharmaceutical portfolio, targeting Tourette syndrome, Alzheimer’s, chronic pain, and epilepsy.

1606 Corp. (OTC: CBDW) is transforming the $327.6B gas station and convenience store industry with AI-powered PRISM+ technology, optimizing logistics, inventory, and operations across 152,396 U.S. locations. By integrating AI-driven analytics, predictive modeling, and real-time optimization, the company is redefining efficiency and profitability in Direct Store Delivery (DSD) solutions. By implementing AI-driven route optimization, predictive inventory management, and machine learning-powered demand forecasting, 1606 Corp. is setting a new benchmark for efficiency and profitability in Direct Store Delivery (DSD) solutions.

Gold Terra Resource Corp. (TSXV: YGT) (OTCQB: YGTFF) is making significant progress in its 2025 wedge drilling program at the Campbell Shear (CS) high-grade gold target on the Con Mine Option (CMO) Property in the Northwest Territories. The first wedge hole, GTCM25-056A, has reached 2,162 metres depth, with the target intersection expected at 2,600 metres, extending below historic high-grade gold zones (5.1 Moz @ 16 g/t). The CMO Property, optioned from Newmont Corporation, remains 100% acquirable by Gold Terra. As drilling progresses, the company aims to confirm new high-grade gold zones to expand its resource potential.

While market uncertainty remains a concern for investors, these small-cap stocks are proving to be resilient by advancing cutting-edge technology, securing key partnerships, and expanding into high-growth markets. With major milestones in AI, biotech, medical devices, mining, and alternative therapeutics, these emerging companies present compelling growth opportunities for investors looking to capitalize on the next big market movers. Keep an eye on STSS, ADTX, CSDX, SPRC, CBDW, YGTFF and CMND, as they continue making waves across industries.

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