About Cabling Installation & Maintenance

Our mission: Bringing practical business and technical intelligence to today's structured cabling professionals

For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

Throughout our annual magazine, weekly email newsletters and 24/7/365 website, Cabling Installation & Maintenance digs into the essential topics our audience focuses on.

  • Design, Installation and Testing: We explain the bottom-up design of cabling systems, from case histories of actual projects to solutions for specific problems or aspects of the design process. We also look at specific installations using a case-history approach to highlight challenging problems, solutions and unique features. Additionally, we examine evolving test-and-measurement technologies and techniques designed to address the standards-governed and practical-use performance requirements of cabling systems.
  • Technology: We evaluate product innovations and technology trends as they impact a particular product class through interviews with manufacturers, installers and users, as well as contributed articles from subject-matter experts.
  • Data Center: Cabling Installation & Maintenance takes an in-depth look at design and installation workmanship issues as well as the unique technology being deployed specifically for data centers.
  • Physical Security: Focusing on the areas in which security and IT—and the infrastructure for both—interlock and overlap, we pay specific attention to Internet Protocol’s influence over the development of security applications.
  • Standards: Tracking the activities of North American and international standards-making organizations, we provide updates on specifications that are in-progress, looking forward to how they will affect cabling-system design and installation. We also produce articles explaining the practical aspects of designing and installing cabling systems in accordance with the specifications of established standards.

Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

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Charles River Launches Endosafe Nexus 200, Emphasizes Critical Importance of Smart Automation for Endotoxin Detection

Next generation robotic endotoxin testing system boosts manufacturing productivity in the lab

Charles River Laboratories International, Inc. (NYSE: CRL) launches the Endosafe® Nexus 200™, expanding its robust endotoxin testing portfolio. The Nexus 200 is the next evolution of Charles River’s data integrity compliant, fully robotic instrument, capable of processing both undiluted or complex, serial dilutions for water, in-process, and final product testing via Endosafe Limulus Amebocyte Lysate (LAL) cartridge technology in a fully enclosed system. Powered by Endosafe EndoScan-V version 6.1, the system allows for data to be exported into a Laboratory Information Management System (LIMS) integration and provides improved traceability, security, and data management on an integrated touch screen.

Automation through robotics represents an evolution of bacterial endotoxin testing and streamlines quality control (QC) processes. Smart automation can improve overall process efficiency, including:

  • Minimizing variation, time, and resources of performing laboratory investigations.
  • Improving workflow of quality control operations, which can reduce product lead times by 60-70 percent, enabling real-time product releases.
  • Avoiding the cost and time needed to train individuals to perform repetitive tasks to allocate to more high-priority tasks, such as interpreting data, analyzing trends, and proactively addressing risks.
  • Reducing the risk for human error in testing processes by implementing automation, leading to greater confidence in product quality and setting a standard of excellence in line with the new revisions to Annex 1.

Unlocking the Benefits of Endosafe LAL Cartridge Technology

Nexus 200 combines technology, innovation, and control to optimize and streamline testing by combining the Endosafe LAL cartridge technology, the Endosafe® nexgen-MCS™ multi-cartridge system, and the Hamilton Microlab® Nimbus platforms for a low-maintenance, high-precision walkaway platform. Charles River’s FDA-licensed LAL cartridge is designed to optimize the standard LAL test. All necessary components are included in the self-contained disposable cartridge, including precise amounts of LAL reagent, chromogenic substrate, and control standard endotoxin (CSE). Cartridges are manufactured in accordance with rigid QC procedures and have been approved by the FDA for in-process and final product release testing.

Approved Quotes

  • “As pharmaceutical manufacturing becomes more efficient, the demand for reliable, compliant, and high-throughput automated bacterial endotoxin solutions increases. Since the launch of Endosafe Nexus in 2014, these demands have inspired our Research and Product Development team to reimagine robotic endotoxin testing with the Endosafe Nexus 200. We are proud of this advancement of our testing portfolio.” –Birgit Girshick, Corporate Executive Vice President & Chief Operating Officer, Charles River
  • “As we move towards future-proofing the micro QC lab, priorities continue to be driven by the need to accommodate increasing sample volumes, data integrity compliance, and evolving regulations, all while focusing on efficiency, quality, and patient safety.” –Gregory Marshall, Vice President and General Manager, Microbial Solutions, Charles River

About Charles River

Charles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit www.criver.com.

Contacts

Investor Contact:

Todd Spencer

Corporate Vice President,

Investor Relations

781.222.6455

todd.spencer@crl.com

Media Contact:

Amy Cianciaruso

Corporate Vice President,

Chief Communications Officer

781.222.6168

amy.cianciaruso@crl.com

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