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For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

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  • Design, Installation and Testing: We explain the bottom-up design of cabling systems, from case histories of actual projects to solutions for specific problems or aspects of the design process. We also look at specific installations using a case-history approach to highlight challenging problems, solutions and unique features. Additionally, we examine evolving test-and-measurement technologies and techniques designed to address the standards-governed and practical-use performance requirements of cabling systems.
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Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

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Lunaphore and Massachusetts General Hospital Pathology Department to Develop Spatial Biology-Based Cancer Diagnostics

Lunaphore, a Swiss life sciences company developing technology to enable spatial biology in every laboratory, today announced it has entered a collaboration with the Pathology Department at Massachusetts General Hospital to develop an in vitro diagnostic (IVD) that evaluates sensitivity of solid tumors to poly-ADP ribose polymerase (PARP) inhibitors, with an initial focus on ovarian, breast and prostate cancers. The project will be led by Markus D. Herrmann, M.D., Ph.D., Director of Computational Pathology at Massachusetts General Hospital, who is also Assistant Professor of Pathology at Harvard Medical School. Lunaphore and Dr. Herrmann will collaborate to develop a multiplexed immunofluorescence assay that can measure the expression of multiple proteins using the COMET platform currently installed at Massachusetts General Hospital.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220217005660/en/

COMET 6-plex on breast cancer [Photo: Lunaphore]

COMET 6-plex on breast cancer [Photo: Lunaphore]

“Spatial biology tools enhance the visualization and quantification of the expression of multiple proteins at once, providing valuable information for treatment decisions,” said Diego G. Dupouy, Ph.D., Chief Technology Officer of Lunaphore. “This partnership will further solidify spatial biology’s role in both improved diagnostics and treatment selection with targeted therapies.”

PARP inhibitors are targeted therapies that are designed to kill cancer cells by preventing them from repairing their damaged DNA. The DNA repair pathway called homologous recombination is of clinical interest as tumors with homologous recombination deficiency (HRD) have been found to be sensitive to PARP inhibitors. However, current methods of identifying HRD in tumors have been varied and imperfect. For example, current biomarker assays are not able to identify epigenetic changes in HRD genes with traditional genotyping assays.

“We look forward to developing a quantitative image-based proteomic assay to comprehensively assess DNA repair at the single-cell level in spatial tissue context and to better predict response to PARP inhibitor therapy,” said Dr. Herrmann. “Adopting spatial biology methods can help us gain pathophysiological insight into the biological processes involved in DNA repair in tumor tissue that may yield clinically actionable biomarkers to improve treatment selection and patient outcomes.”

To learn more about Lunaphore, please visit: https://lunaphore.com/

About Lunaphore

Lunaphore Technologies S.A. is a Swiss company born in 2014 with the vision of enabling spatial biology in every laboratory. Lunaphore has developed a game-changing chip technology which can extract spatial proteomic and genomic data from tumors and transform any simple assay into multiplex spatial biology without complexity. Lunaphore empowers researchers to push the boundaries of research to ultimately develop the next generation personalized therapies. For further information on Lunaphore and its products, please visit www.lunaphore.com.

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