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For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

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Thermo Fisher Scientific Signs Companion Diagnostic Agreement with Boehringer Ingelheim to Select Patients with NSCLC for Targeted Therapy Treatment

Collaboration leverages two CDx assays from Thermo Fisher to support greater access to genomic testing for cancer patients in Japan and the United States

To support emerging precision therapies and improve patient outcomes by increasing access to reliable genomic testing needed to match patients with targeted cancer treatments, Thermo Fisher Scientific today announced a companion diagnostic (CDx) partnership with Boehringer Ingelheim. Through this collaboration, the companies will work to develop CDx tests to help identify patients with non-small cell lung cancer (NSCLC) with specific genomic mutations.

Lung cancer is one of the most common cancers, with 2.2 million cases worldwide in 2020 and is the leading cause of cancer death in both Japani and the U.S.ii The collaboration will leverage the Oncomine Dx Express Test* on the Ion Torrent Genexus Dx System* as well as the Oncomine Dx Target Test.**

“Our proven track record of co-developing CDx tests reinforces our commitment to working with leading pharma companies to ensure patients may have immediate access to these targeted therapies once approved,” said Garret Hampton, president of clinical next-generation sequencing and oncology at Thermo Fisher Scientific. “Boehringer Ingelheim has made a generational commitment to transforming cancer care, and we’re excited to be supporting their pipeline as they work to ensure the appropriate tests are available to match eligible patients with emerging targeted therapies.”

Boehringer Ingelheim has the aspiration to transform the lives of people with cancer by delivering meaningful advances, with the ultimate goal of curing a range of cancers. By partnering with Thermo Fisher, Boehringer Ingelheim aims to develop multiple companion diagnostic tests to ensure that labs using a variety of testing technologies will have the ability to match eligible patients with emerging NSCLC treatments as they become available.

A recently published, real-world study in stage 4 NSCLC found that patients whose treatments were initiated before genomic insights were available experienced inferior outcomes, supporting the need for more rapid molecular testing.iii Thermo Fisher’s Oncomine Dx Express Test in combination with the Genexus Dx System offers a fully integrated, NGS platform that can test a patient’s tumor biopsy or blood specimen, returning actionable results in as little as 24 hours. The Genexus Dx System delivers a turnkey, end-to-end NGS system that requires as little as 10 minutes of hands-on time, simplifying the testing workflow and making this technology feasible for more labs.

The Oncomine Dx Target Test remains the only distributed NGS CDx kit that has received regulatory approval and is available in 18 countries worldwide for 17 targeted therapies.

*The Genexus Dx instrument and the Oncomine Dx Express Test are currently CE-IVD and only available to those countries who accept the CE-IVD mark.

**The Oncomine Dx Target Test is for In Vitro Diagnostic use

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue over $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our global team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit www.thermofisher.com.

i https://tlcr.amegroups.org/article/view/35680/html

ii https://www.cdc.gov/cancer/lung/statistics/index.htm

iii https://ascopubs.org/doi/full/10.1200/OP.22.00611

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