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For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

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Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

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Thermo Fisher Scientific Launches PangenomiX Array to Support Population-Scale Disease Studies and Pharmacogenomics Research

Most comprehensive and ethnically diverse genomic coverage on a high throughput microarray delivers multi-disease and pharmacogenomic research analysis across global populations

Earlier this year, scientists unveiled the first draft of the pangenome, based on full genetic blueprints from 47 people around the world to create a more diverse representation of the human genome1. To more accurately account for this richer picture of human genomic variation, Thermo Fisher Scientific has launched the new Axiom™ PangenomiX Array*, its largest and most ethnically diverse array to date, offering optimal genetic coverage for population scale disease studies and pharmacogenomic research.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20240104569788/en/

Most comprehensive and ethnically diverse genomic coverage on a high throughput microarray delivers multi-disease and pharmacogenomic research analysis across global populations. (Photo: Business Wire)

Most comprehensive and ethnically diverse genomic coverage on a high throughput microarray delivers multi-disease and pharmacogenomic research analysis across global populations. (Photo: Business Wire)

Current large scale genomic datasets, which are used for downstream meta-analysis to build and understand disease risk prediction models, are predominantly based off European and Caucasian cohorts. With an increasingly diverse and blended global community, there is an urgent need for ethnically diverse data sets to drive genetic insights in other populations, such as African, Asian and increasing mixed populations. Furthermore, the healthcare industry is increasingly moving toward a proactive care model, highlighting the importance of conducting research on the role of genetics in disease risk and drug response.

The PangenomiX Array is currently the only research solution that combines four assays in one test: SNP genotyping, whole genome copy number variant detection, fixed copy number discovery, blood and HLA typing. The high-throughput array is designed to advance disease risk and detection research, population-scale disease research programs, ancestry and wellness testing, drug efficacy testing, and drug development research.

Inclusive of clinically relevant pharmacogenomic markers and pathogenic variants, the PangenomiX Array offers researchers enhanced whole-genome imputation and a high level of diversity for testing different ethnicities to keep pace with the growing understanding of the genome. The array has already been used to analyze nearly half a million ethnically diverse samples at a predominant biobank in the U.S. to advance more inclusive research studies related to the prevention, diagnosis and treatment of disease.

“With more diverse genomic data sets, population-scale testing for diseases is reaching even greater heights with long-term ramifications for our understanding of human disease, drug development, pharmacogenomics and ancestry,” said Kim Caple, president, genetic sciences, Thermo Fisher Scientific. “The research projects underway today will usher in a new standard of care for the future, with healthcare providers routinely using patients’ genetic information to predict disease risk and improve treatment decision-making. With its depth and breadth of coverage, the PangenomiX Array offers a cost-effective, accurate and reproducible solution that builds on our 30+ years in dedicated microarray research and testing with the goal of powering research that helps people live longer, healthier lives.”

To learn more about the PangenomiX Array, please visit our website: www.thermofisher.com/PangenomiX

*The PangenomiX Array is for research use only. Not for use in diagnostic procedures.

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue over $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our global team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit www.thermofisher.com

1 https://www.nytimes.com/2023/05/10/science/pangenome-human-dna-genetics.html

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