About Cabling Installation & Maintenance

Our mission: Bringing practical business and technical intelligence to today's structured cabling professionals

For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

Throughout our annual magazine, weekly email newsletters and 24/7/365 website, Cabling Installation & Maintenance digs into the essential topics our audience focuses on.

  • Design, Installation and Testing: We explain the bottom-up design of cabling systems, from case histories of actual projects to solutions for specific problems or aspects of the design process. We also look at specific installations using a case-history approach to highlight challenging problems, solutions and unique features. Additionally, we examine evolving test-and-measurement technologies and techniques designed to address the standards-governed and practical-use performance requirements of cabling systems.
  • Technology: We evaluate product innovations and technology trends as they impact a particular product class through interviews with manufacturers, installers and users, as well as contributed articles from subject-matter experts.
  • Data Center: Cabling Installation & Maintenance takes an in-depth look at design and installation workmanship issues as well as the unique technology being deployed specifically for data centers.
  • Physical Security: Focusing on the areas in which security and IT—and the infrastructure for both—interlock and overlap, we pay specific attention to Internet Protocol’s influence over the development of security applications.
  • Standards: Tracking the activities of North American and international standards-making organizations, we provide updates on specifications that are in-progress, looking forward to how they will affect cabling-system design and installation. We also produce articles explaining the practical aspects of designing and installing cabling systems in accordance with the specifications of established standards.

Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

Contact Cabling Installation & Maintenance

Editorial

Patrick McLaughlin

Serena Aburahma

Advertising and Sponsorship Sales

Peter Fretty - Vice President, Market Leader

Tim Carli - Business Development Manager

Brayden Hudspeth - Sales Development Representative

Subscriptions and Memberships

Subscribe to our newsletters and manage your subscriptions

Feedback/Problems

Send a message to our general in-box

 

Beacon Biosignals Announces Strategic Collaboration with Skye Bioscience to Integrate Sleep Quality and Sleep Apnea Endpoints in CBEYOND™ Phase 2 Trial of Nimacimab for Obesity

BOSTON and SAN DIEGO, July 24, 2024 (GLOBE NEWSWIRE) -- Beacon Biosignals, a leader in at-home sleep monitoring and computational neurodiagnostics, today announced a strategic collaboration with Skye Bioscience, Inc. (Nasdaq: SKYE), a pharmaceutical company focused on unlocking new therapeutic pathways for metabolic health, to enhance its upcoming CBEYOND™ Phase 2 clinical trial of Nimacimab. This partnership will incorporate sleep quality and sleep apnea endpoints via the Beacon Platform and the FDA 510(k)-cleared Dreem 3S EEG device to better understand the comprehensive impact of Nimacimab on patients with obesity.

Nimacimab, a negative allosteric-modulating antibody that inhibits the peripheral cannabinoid 1 (CB1) receptor, is currently being investigated for its potential to address obesity and cardiometabolic disease. Obstructive sleep apnea is an important comorbidity associated with obesity, with apneic events and intermittent hypoxia driving sympathetic activation and fragmented sleep with nocturnal awakenings.

Dreem3S Bedside

The addition of quantitative sleep-related endpoints aims to establish a comprehensive view of the therapeutic benefits of Nimacimab, given the linkage between metabolic conditions, disturbed sleep, and neurocognitive function. By integrating Beacon's advanced sleep monitoring technology platform, the planned Phase 2 trial will assess and quantify improvements in sleep patterns and apnea events, such as sleep efficiency and the apnea-hypopnea index (AHI).

"We are thrilled to collaborate with Skye Bioscience to bring our expertise in sleep monitoring and analysis to this important clinical trial," said Jacob Donoghue, MD, PhD, CEO of Beacon Biosignals. "Our FDA-cleared Dreem 3S EEG headband and AI-powered analytics platform will enable the collection of clinically-validated sleep assessments from patients in their own homes. This will provide valuable insights into how Nimacimab may improve sleep quality and reduce sleep apnea, conditions often comorbid with obesity and cardiometabolic disease."

"Understanding the multifaceted impact of Nimacimab on our target patient population is crucial because there is a growing list of diseases that have demonstrated benefit from effective treatment of obesity, including obstructive sleep apnea," said Punit Dhillon, CEO of Skye Bioscience. "Collaborating with Beacon Biosignals allows us to leverage their cutting-edge technology to monitor sleep quality and apnea, providing a more comprehensive assessment of Nimacimab's therapeutic potential early in the drug’s development. This collaboration represents a significant step in our commitment to addressing the complexities of obesity."

Obstructive sleep apnea affects up to 40 million Americans, with an estimated 82-93% of individuals remaining undiagnosed. Of those treated, up to 38% of patients are not adherent to traditional continuous positive airway pressure (CPAP) therapy (Rotenberg et al., 2016). Donoghue added, "There is tremendous unmet patient need for those with obstructive sleep apnea. Next-generation weight loss therapies hold the promise to catalyze new, patient-centric clinical paradigms that can impact millions of people."

References

André, S., Andreozzi, F., Van Overstraeten, C. et al. Cardiometabolic comorbidities in obstructive sleep apnea patients are related to disease severity, nocturnal hypoxemia, and decreased sleep quality. Respir Res 21, 35 (2020).

Rotenberg BW, Murariu D, Pang KP. Trends in CPAP adherence over twenty years of data collection: a flattened curve. J Otolaryngol Head Neck Surg. 2016 Aug 19;45(1):43.

About Beacon Biosignals

Beacon Biosignals is the leading at-home EEG platform for precision drug development. Its FDA 510(k)-cleared Dreem 3S EEG headband algorithms enable and accelerate research and development of treatments that transform the lives of patients with neurological, psychiatric, and sleep disorders. Beacon’s Clinico-EEG database contains over 100,000 patients’ brain activity data, and its cloud-native analytics platform empowers rapid interrogation of brain activity to support retrospective and prospective studies. For more information, visit [beacon.bio](https://www.beacon.bio).

About Skye Bioscience

Skye is focused on unlocking new therapeutic pathways for metabolic health. Backed by specialist life science investors, Skye's strategy leverages biologic targets with substantial human proof of mechanism for the development of first-in-class therapeutics with clinical and commercial differentiation. Skye plans to start a Phase 2 clinical trial in obesity in Q3 2024 for Nimacimab, a negative allosteric modulating antibody that peripherally inhibits CB1, comparing monotherapy and combination arms of Nimacimab and a GLP-1R agonist. For more information, please visit: https://www.skyebioscience.com.

For Beacon Biosignals media inquiries, please contact:

Dan Florey
Beacon Biosignals
Email: info@beacon.bio
X: https://x.com/Biosignals
LinkedIn: https://www.linkedin.com/company/beacon-biosignals

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/4457a080-bc24-4006-b2b8-395a3454f4ce


Primary Logo

Stock Quote API & Stock News API supplied by www.cloudquote.io
Quotes delayed at least 20 minutes.
By accessing this page, you agree to the following
Privacy Policy and Terms Of Service.