Ann Arbor, MI – AgelessRx, a leading telehealth longevity platform, today announced the rollout of its SGLT2 inhibitor therapy program, introducing Invokana® (canagliflozin) and Brenzavvy® (bexagliflozin) as clinically vetted tools for metabolic reset, anti-aging pathways, and overall healthspan extension. These offerings bring cutting-edge science into the standard of care for individuals seeking proven longevity benefits beyond traditional blood sugar control.

Overview of SGLT2 Inhibitors at AgelessRx

SGLT2 (sodium-glucose co-transporter-2) inhibitors work by reducing glucose reabsorption in the kidneys, allowing the body to naturally eliminate excess glucose through urine. This mechanism helps to:

• Flush out approximately 50-80 grams of excess glucose per day, which is roughly equivalent to the sugar content in two cans of soda. 
• Create a metabolic shift mimicking caloric restriction, one of the most widely studied interventions for longevity. 
• Activate nutrient-sensing longevity pathways including mTOR, AMPK, and SIRT1. 

Products Being Offered

Invokana® (Canagliflozin)

• Designed to not only manage glucose but also to support heart and kidney health and reduce inflammation and oxidative stress. 
• Demonstrated in animal models to extend lifespan, mimicking caloric restriction. 
• Potential side benefits include moderate weight loss (2-4% of body weight), lowering risk of dementia and Parkinson’s disease, and elimination of senescent cells. 

Brenzavvy® (Bexagliflozin)

• FDA-approved in 2023 for type 2 diabetes; shares the same foundational mechanism as other SGLT2 inhibitors. 
• Promising longevity-oriented benefits under investigation, overlapping with those of Invokana® in the reduction of inflammation, oxidative stress, improving metabolic health, and potentially lowering risks of age-related disease. 
• More affordable entry point for patients seeking SGLT2 therapy as part of a longevity regimen.

Clinical & Longevity Benefits

AgelessRx emphasizes that the value of SGLT2 inhibitors extends beyond glucose regulation. Research has consistently shown that these therapies offer measurable cardiovascular and kidney protection, especially for individuals facing metabolic risk factors. This makes them a promising option not only for those managing diabetes but also for those seeking preventive tools that support long-term health.

Evidence from both preclinical and clinical studies indicates that SGLT2 inhibitors help reduce inflammation and oxidative stress, two biological processes closely linked to aging. By lowering these drivers of cellular damage, the therapy may contribute to healthier aging and improved resilience against age-related decline.

Safety and Oversight

All SGLT2 inhibitor therapy through AgelessRx is overseen by U.S.-licensed prescribers to ensure patient safety. Each program begins with a 100% online medical evaluation to confirm suitability for treatment. Patients then receive personalized dosing plans, along with ongoing follow-ups and professional support throughout their journey.

AgelessRx also provides clear, accessible guidance regarding possible side effects - such as increased urination, dehydration, urinary tract infections, or hypotension - and outlines situations where therapy may not be recommended. This combination of clinical oversight and patient education ensures a responsible, transparent approach to longevity care.

For more information about SGLT2 inhibitors: https://agelessrx.com/how-do-sglt2-inhibitors-work/

About AgelessRx

AgelessRx is at the forefront of the longevity revolution, offering clinically validated cutting-edge solutions and preventive treatments aimed at extending life expectancy and enhancing quality of life. AgelessRx also continues to advance the field of longevity science by conducting ongoing research and clinical trials. Through its online platform, AgelessRx provides easy access to innovative healthcare services, with an emphasis on customer satisfaction, affordability, and the pursuit of a future where extended healthspan is a reality for everyone. 

Email: press@agelessrx.com

Media Contact

Name
AgelessRx
Contact name
Anar Isman
Contact phone
650-503-9990
Contact address
2370 E Stadium Blvd #2049
City
Ann Arbor
State
MI
Zip
48104
Country
United States
Url
https://agelessrx.com/