The markets opened mixed with the Dow slipping 10 points to 18,527 ahead of Apple's iPhone event. Nasdaq rose 10 points to 5,285.
On the upside
Retrophin (Nasdaq: RTRX) reported positive results from a Phase 2 DUET study of sparsentan to treat focal segmental glomerulosclerosis.
A new drug application will be filed for Agios Pharmaceuticals' (Nasdaq: AGIO) AG-221 by development partner Celgene.
Scientific Games (Nasdaq: SGMS) designated its wholly owned interactive social gaming subsidiaries as unrestricted subsidiaries.
On the downside
Sprouts Farmers Market (Nasdaq: SPFM) cut its third quarter revenue forecast and its full year revenue and earnings guidance.
Second quarter earnings and revenue for HD Supply Holdings (Nasdaq: HDS) fell short of expectations.
First quarter revenue fell for Casey's General Stores (Nasdaq: CASY).
In the broad market, advancing issues outpaced decliners by a margin of nearly 5 to 4 on the NYSE and by more than 7 to 5 on Nasdaq. The broader S&P 500 added a point to 2,187. Bitcoin added $1 to $609.