About Cabling Installation & Maintenance

Our mission: Bringing practical business and technical intelligence to today's structured cabling professionals

For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

Throughout our annual magazine, weekly email newsletters and 24/7/365 website, Cabling Installation & Maintenance digs into the essential topics our audience focuses on.

  • Design, Installation and Testing: We explain the bottom-up design of cabling systems, from case histories of actual projects to solutions for specific problems or aspects of the design process. We also look at specific installations using a case-history approach to highlight challenging problems, solutions and unique features. Additionally, we examine evolving test-and-measurement technologies and techniques designed to address the standards-governed and practical-use performance requirements of cabling systems.
  • Technology: We evaluate product innovations and technology trends as they impact a particular product class through interviews with manufacturers, installers and users, as well as contributed articles from subject-matter experts.
  • Data Center: Cabling Installation & Maintenance takes an in-depth look at design and installation workmanship issues as well as the unique technology being deployed specifically for data centers.
  • Physical Security: Focusing on the areas in which security and IT—and the infrastructure for both—interlock and overlap, we pay specific attention to Internet Protocol’s influence over the development of security applications.
  • Standards: Tracking the activities of North American and international standards-making organizations, we provide updates on specifications that are in-progress, looking forward to how they will affect cabling-system design and installation. We also produce articles explaining the practical aspects of designing and installing cabling systems in accordance with the specifications of established standards.

Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

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Cadence Unveils AI-Driven ROCS X AI-Enabled Molecular Search, Unlocking Multi-trillion Molecule Virtual Screening

Treeline Biosciences validates breakthrough with discovery of more than 150 synthesizable drug candidates in novel chemical space

OpenEye miniCUP--Cadence Molecular Sciences (OpenEye), a business unit of Cadence (Nasdaq: CDNS), announced today at miniCUP Boston, the launch of ROCS X, an AI-enabled virtual-- screening solution that allows scientists to conduct 3D searches of trillions of drug-like molecules. The ROCS X technology was developed and validated through collaboration with Treeline Biosciences, a biotechnology firm focused on addressing serious medical conditions such as cancer. Utilizing ROCS X, Treeline has physically sourced over 150 novel compounds for evaluation as potential drug candidates.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250925980347/en/

Cadence Molecular Sciences (OpenEye), a business unit of Cadence, announced the launch of ROCS X, an AI-enabled virtual screening solution that allows scientists to conduct 3D searches of trillions of drug-like molecules.

Cadence Molecular Sciences (OpenEye), a business unit of Cadence, announced the launch of ROCS X, an AI-enabled virtual screening solution that allows scientists to conduct 3D searches of trillions of drug-like molecules.

“We were challenged by Treeline Biosciences to build and create search capabilities for databases of 3D synthetically accessible drug-like molecules at an unprecedented scale,” said Geoff Skillman, vice president, Research & Development, Cadence Molecular Sciences. “Industry data shows—and we continue to demonstrate—that searching a larger chemical space yields more diverse compounds and more unique scaffolds, enabling customers to accelerate discovery of potential drug candidates.”

ROCS X achieves this breakthrough by building on the Cadence® Orion® Molecular Design Platform, uniting the proven OpenEye OMEGA conformer generation and ROCS® (Rapid Overlay of Chemical Structures) virtual screening software products with AI-enabled 3D search. This powerful combination delivers reliable, efficient, and computationally affordable shape and electrostatic overlays from trillions of molecules. By creating 3D representations of molecules along with electrostatics, ROCS X delivers a performance increase of at least three orders of magnitude over current approaches, outperforming other technologies that claim 3D search or rely on feature trees.

“Using Cadence ROCS X, scientists at Treeline can now search trillions of drug-like molecules—an achievement that was unimaginable just a few years ago,” said Eric Manas, senior vice president of Medicine Design, Treeline Biosciences. “By running ROCS X, we've identified novel chemical matter leading to promising 3D ligand-protein structures across multiple drug discovery projects.”

In a validation experiment, ROCS X was compared to traditional FastROCS enumerated search and found 97% identical molecules from a set of 1,000. Customers can use these industry-leading methods to search over a thousand times more molecules in the synthon space. As such, Treeline has identified a variety of molecules with consistently high synthetic success rates and multiple experimental structures of hits bound to targets.

Early access to ROCS X is available now, with general availability expected in the first quarter of 2026. To request advanced access, please contact oe-sales@cadence.com. To learn more about Cadence Molecular Sciences (OpenEye) and its technologies, please visit https://www.cadence.com/openeye.

About Cadence

Cadence is a market leader in AI and digital twins, pioneering the application of computational software to accelerate innovation in the engineering design of silicon to systems. Our design solutions, based on Cadence’s Intelligent System Design strategy, are essential for the world’s leading semiconductor and systems companies to build their next-generation products from chips to full electromechanical systems that serve a wide range of markets, including hyperscale computing, mobile communications, automotive, aerospace, industrial, drug design and robotics. In 2024, Cadence was recognized by the Wall Street Journal as one of the world’s top 100 best-managed companies. Cadence solutions offer limitless opportunities—learn more at www.cadence.com.

© 2025 Cadence Design Systems, Inc. All rights reserved worldwide. Cadence, the Cadence logo and the other Cadence marks found at www.cadence.com/go/trademarks are trademarks or registered trademarks of Cadence Design Systems, Inc. All other trademarks are the property of their respective owners.

Category: Featured

Industry data shows—and we continue to demonstrate—that searching a larger chemical space yields more diverse compounds and more unique scaffolds, enabling customers to accelerate discovery of potential drug candidates.

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