About Cabling Installation & Maintenance

Our mission: Bringing practical business and technical intelligence to today's structured cabling professionals

For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

Throughout our annual magazine, weekly email newsletters and 24/7/365 website, Cabling Installation & Maintenance digs into the essential topics our audience focuses on.

  • Design, Installation and Testing: We explain the bottom-up design of cabling systems, from case histories of actual projects to solutions for specific problems or aspects of the design process. We also look at specific installations using a case-history approach to highlight challenging problems, solutions and unique features. Additionally, we examine evolving test-and-measurement technologies and techniques designed to address the standards-governed and practical-use performance requirements of cabling systems.
  • Technology: We evaluate product innovations and technology trends as they impact a particular product class through interviews with manufacturers, installers and users, as well as contributed articles from subject-matter experts.
  • Data Center: Cabling Installation & Maintenance takes an in-depth look at design and installation workmanship issues as well as the unique technology being deployed specifically for data centers.
  • Physical Security: Focusing on the areas in which security and IT—and the infrastructure for both—interlock and overlap, we pay specific attention to Internet Protocol’s influence over the development of security applications.
  • Standards: Tracking the activities of North American and international standards-making organizations, we provide updates on specifications that are in-progress, looking forward to how they will affect cabling-system design and installation. We also produce articles explaining the practical aspects of designing and installing cabling systems in accordance with the specifications of established standards.

Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

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1ST Biotherapeutics, Inc. Announces First Patient Dosed in Phase I/II Study of HPK1 Inhibitor FB849 in Patients with Advanced Solid Tumors

YONGIN, South Korea, December 14, 2023 – 1ST Biotherapeutics, Inc., a clinical-stage biotechnology company focused on the development of novel small molecule therapeutics in neurodegenerative diseases, immuno-oncology, and rare diseases, today announced the first patient dosing in the clinical Phase I/II trial evaluating FB849 in patients with advanced solid tumors.

"We are excited to announce the initiation of a first-in-human trial of FB849 with the dosing of the first patient,” said Seongkon Kim, Ph.D., Chief Technology Officer of 1ST Biotherapeutics. “FB849 has emerged as a promising immunotherapy agent with extreme selectivity, leading to potent anti-tumor responses and durable effect. It has the potential to address a high unmet need in the immune-oncology space - not only as a monotherapy, but also in combination with checkpoint inhibitors.”

The clinical Phase I/II trial is an open-label study designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of FB849 as a monotherapy and in combination with KEYTRUDA for the treatment of advanced solid tumors (NCT05761223). 1ST Biotherapeutics remains committed to rigorous clinical investigation and looks forward to sharing updates as the trial progresses.

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About FB849

FB849 is 1ST Biotherapeutic’s proprietary small molecule inhibitor of hematopoietic progenitor kinase 1 (HPK1) as a novel, next-generation immuno-oncology agent. In preclinical studies, it has been demonstrated that FB849’s highly selective inhibition of HPK1 induces potent anti-cancer immunity via cross-spectrum immune cell invigoration, including T cells, B cells, dendritic cells, and macrophages, with robust and durable effects in tumor growth inhibition.

About 1ST Biotherapeutics, Inc.

1ST Biotherapeutics, Inc. is a pioneering clinical-stage biotechnology company focused on developing transformative small molecule therapeutics for neurodegenerative diseases, immuno-oncology, and rare diseases. Committed to innovation and patient-centric approaches, the company endeavors to redefine treatment paradigms and improve patient outcomes.

Contact 1ST Biotherapeutics, Inc.
info@1stbio.com
Tel. +82 31 8023 5332

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