About Us

Laser Focus World is an industry bedrock—first published in 1965 and still going strong. We publish original articles about cutting-edge advances in lasers, optics, photonics, sensors, and quantum technologies, as well as test and measurement, and the shift currently underway to usher in the photonic integrated circuits, optical interconnects, and copackaged electronics and photonics to deliver the speed and efficiency essential for data centers of the future.

Our 80,000 qualified print subscribers—and 130,000 12-month engaged online audience—trust us to dive in and provide original journalism you won’t find elsewhere covering key emerging areas such as laser-driven inertial confinement fusion, lasers in space, integrated photonics, chipscale lasers, LiDAR, metasurfaces, high-energy laser weaponry, photonic crystals, and quantum computing/sensors/communications. We cover the innovations driving these markets.

Laser Focus World is part of Endeavor Business Media, a division of EndeavorB2B.

Laser Focus World Membership

Never miss any articles, videos, podcasts, or webinars by signing up for membership access to Laser Focus World online. You can manage your preferences all in one place—and provide our editorial team with your valued feedback.

Magazine Subscription

Can you subscribe to receive our print issue for free? Yes, you sure can!

Newsletter Subscription

A Laser Focus World newsletter subscription is free to qualified professionals:

The Daily Beam

Showcases the newest content from Laser Focus World, including photonics- and optics-based applications, components, research, and trends. (Daily)

Product Watch

The latest in products within the photonics industry. (9x per year)

Bio & Life Sciences Product Watch

The latest in products within the biophotonics industry. (4x per year)

Laser Processing Product Watch

The latest in products within the laser processing industry. (3x per year)

Get Published!

If you’d like to write an article for us, reach out with a short pitch to Sally Cole Johnson: [email protected]. We love to hear from you.

Photonics Hot List

Laser Focus World produces a video newscast that gives a peek into what’s happening in the world of photonics.

Following the Photons: A Photonics Podcast

Following the Photons: A Photonics Podcast dives deep into the fascinating world of photonics. Our weekly episodes feature interviews and discussions with industry and research experts, providing valuable perspectives on the issues, technologies, and trends shaping the photonics community.

Social Media

Bluesky • Facebook • Instagram • LinkedIn • YouTube

Meet the Laser Focus World Team

Editorial

Sales

Editorial Advisory Board

  • Professor Andrea M. Armani, University of Southern California
  • Ruti Ben-Shlomi, Ph.D., LightSolver
  • James Butler, Ph.D., Hamamatsu
  • Natalie Fardian-Melamed, Ph.D., Columbia University
  • Justin Sigley, Ph.D., AmeriCOM
  • Professor Birgit Stiller, Max Planck Institute for the Science of Light, and Leibniz University of Hannover
  • Professor Stephen Sweeney, University of Glasgow
  • Mohan Wang, Ph.D., University of Oxford
  • Professor Xuchen Wang, Harbin Engineering University
  • Professor Stefan Witte, Delft University of Technology
Recent Quotes
My Watchlist
Indicators
Industrial Laser Index
Markets
Stocks
ETFs
Tools
Markets:
Overview
News
Currencies
International
Treasuries

Landmark Study Identifies Prognostic Biomarkers in Duchenne Muscular Dystrophy Using Large-Scale Serum Proteomics

By: ACCESS Newswire

Published in Nature Communications, a new study uncovers critical protein biomarkers that predict functional decline in Duchenne Muscular Dystrophy (DMD), opening doors to more personalized care and improved clinical trials.

LEIDEN, THE NETHERLANDS, GAINESVILLE, FL, AND NEW YORK, NY, CA / ACCESS Newswire / October 16, 2025 / In a major advancement for Duchenne muscular dystrophy (DMD) research and patient care, a multi-institutional team led by investigators from Leiden University Medical Center, the University of Florida and BioSymetrics Inc (a subsidiary of Lunai Bioworks Inc.; NASDAQ: LNAI) has identified serum proteins that can serve as prognostic biomarkers in DMD. The study, published today in Nature Communications and supported by Parent Project Muscular Dystrophy (PPMD), analyzed over 700 longitudinal serum samples using the SomaScan® proteomics platform.

The research represents one of the most comprehensive proteomic efforts in DMD to date, integrating rich longitudinal data from two independent cohorts - one in Europe and one in the United States. Leveraging statistical modeling and cross-cohort validation, the team identified a set of proteins, including RGMA, ART3, and ANTXR2, that are not only associated with motor performance but also reliably predict disease progression, such as loss of ambulation and upper limb function.

"Monitoring progression of DMD patients in natural history studies and clinical trials has been historically done using clinical scales and timed tests that have been shown to be dependent on patients' motivation. This study shows that proteins in serum offer a valid alternative to monitor disease progression," said Dr. Pietro Spitali, an Associate Professor of human genetics at Leiden University Medical Center. "It has been a great pleasure to work on the project with this multidisciplinary team and I am looking forward to seeing how our data will be used by other groups to monitor their patients and to improve clinical trials design."

These findings are expected to contribute to earlier and more individualized interventions in clinical settings, and to refine enrollment and stratification strategies in clinical trials by identifying patients more likely to experience disease progression.

"Identifying robust, minimally invasive prognostic biomarkers in Duchenne muscular dystrophy has been a long-standing challenge for the field," said Dr. Glenn Walter, a professor of physiology and aging at the University of Florida. "This study represents a significant step forward, as these serum-based protein biomarkers not only enable the prediction of disease progression with a simple blood test but can also be integrated with other patient-specific data, including genetic and clinical information. The ability to combine these approaches will help facilitate more personalized management strategies, optimize clinical trial design, and ultimately improve outcomes for individuals living with DMD."

"We are greatly encouraged by these initial findings from this collaborative proteomics study," said Dr. Eric Camino, the vice president of research and clinical innovation at PPMD. "There is a critical need to identify biomarkers that can inform us about individual patient trajectories within such a heterogenous disease to enhance patient care and potentially impact therapy development."

BioSymetrics, a data science and AI company specializing in biomedical analytics, provided key analytical support and led the integration of clinical and proteomic data. Their advanced modeling capabilities enabled the discovery of statistically robust and biologically plausible biomarkers, while controlling for critical confounders such as age and corticosteroid use.

"We're proud to have played a role in this transformative project," said Dr. Gabe Musso, the Chief Scientific Officer of BioSymetrics. "This study is a great example of how collaboration between academia and industry can produce clinically actionable insights."

About the Study

  • Title: Large-scale serum protein biomarkers discovery associated with function and clinical milestones in Duchenne muscular dystrophy

  • Journal: Nature Communications

  • Link:https://www.nature.com/articles/s41467-025-64146-y

  • Publication Date: October 13th, 2025

  • Funding: Parent Project Muscular Dystrophy, Spieren voor Spieren and the U.S. NIH (NINDS, CTSI)

About Lunai Bioworks

Lunai Bioworks Inc. is an AI-powered drug discovery and biodefense company pioneering safe and responsible generative biology. With proprietary neurotoxicity datasets, advanced machine learning, and a focus on dual-use risk management, Lunai is redefining how artificial intelligence can accelerate therapeutic innovation while safeguarding society from emerging threats.

Media Contact:

David Weinstein
Chief Executive Officer
305-918-1980
ir@lunaibioworks.com
http://www.lunaibioworks.com/

SOURCE: Lunai Bioworks Inc.



View the original press release on ACCESS Newswire

More News

View More
Johnson & Johnson's M&A Strategy Is the Real Story for Investors
Via MarketBeat
Tickers JNJ KVUE PTGX
Tesla: Some Analysts Are Calling for A 30% Drop—Time to Panic?
Via MarketBeat
Topics Artificial Intelligence
Tickers TSLA
Hedge Funds Flip on the Dollar—A Buy Signal for These 3 Stocks?
Via MarketBeat
Topics Bonds Stocks World Trade
Tickers ABNB DAL DOW HD
Happy Third Birthday to the Bull Market
Via MarketBeat
Topics Artificial Intelligence Stocks
Tickers NVDA PLTR TSLA
MarketBeat Week in Review – 10/13 - 10/17
Via MarketBeat
Topics Artificial Intelligence Economy World Trade
Tickers ACHR AMZN APLD APP ASTS CRM

Recent Quotes

View More
Symbol Price Change (%)
AMZN  213.04
-1.43 (-0.67%)
AAPL  252.29
+4.84 (1.96%)
AMD  233.08
-1.48 (-0.63%)
BAC  51.28
+0.84 (1.67%)
GOOG  253.79
+1.91 (0.76%)
META  716.91
+4.84 (0.68%)
MSFT  513.58
+1.97 (0.39%)
NVDA  183.16
+1.35 (0.74%)
ORCL  291.31
-21.69 (-6.93%)
TSLA  439.31
+10.56 (2.46%)
Stock Quote API & Stock News API supplied by www.cloudquote.io
Quotes delayed at least 20 minutes.
By accessing this page, you agree to the Privacy Policy and Terms Of Service.
© 2025 FinancialContent. All rights reserved.