Laser Focus World is an industry bedrock—first published in 1965 and still going strong. We publish original articles about cutting-edge advances in lasers, optics, photonics, sensors, and quantum technologies, as well as test and measurement, and the shift currently underway to usher in the photonic integrated circuits, optical interconnects, and copackaged electronics and photonics to deliver the speed and efficiency essential for data centers of the future.

Our 80,000 qualified print subscribers—and 130,000 12-month engaged online audience—trust us to dive in and provide original journalism you won’t find elsewhere covering key emerging areas such as laser-driven inertial confinement fusion, lasers in space, integrated photonics, chipscale lasers, LiDAR, metasurfaces, high-energy laser weaponry, photonic crystals, and quantum computing/sensors/communications. We cover the innovations driving these markets.

Laser Focus World is part of Endeavor Business Media, a division of EndeavorB2B.

Laser Focus World Membership

Never miss any articles, videos, podcasts, or webinars by signing up for membership access to Laser Focus World online. You can manage your preferences all in one place—and provide our editorial team with your valued feedback.

Magazine Subscription

Can you subscribe to receive our print issue for free? Yes, you sure can!

Newsletter Subscription

Laser Focus World newsletter subscription is free to qualified professionals:

The Daily Beam

Showcases the newest content from Laser Focus World, including photonics- and optics-based applications, components, research, and trends. (Daily)

Product Watch

The latest in products within the photonics industry. (9x per year)

Bio & Life Sciences Product Watch

The latest in products within the biophotonics industry. (4x per year)

Laser Processing Product Watch

The latest in products within the laser processing industry. (3x per year)

Get Published!

If you’d like to write an article for us, reach out with a short pitch to Sally Cole Johnson: [email protected]. We love to hear from you.

Photonics Hot List

Laser Focus World produces a video newscast that gives a peek into what’s happening in the world of photonics.

Following the Photons: A Photonics Podcast

Following the Photons: A Photonics Podcast dives deep into the fascinating world of photonics. Our weekly episodes feature interviews and discussions with industry and research experts, providing valuable perspectives on the issues, technologies, and trends shaping the photonics community.

Editorial Advisory Board

  • Professor Andrea M. Armani, University of Southern California
  • Ruti Ben-Shlomi, Ph.D., LightSolver
  • James Butler, Ph.D., Hamamatsu
  • Natalie Fardian-Melamed, Ph.D., Columbia University
  • Justin Sigley, Ph.D., AmeriCOM
  • Professor Birgit Stiller, Max Planck Institute for the Science of Light, and Leibniz University of Hannover
  • Professor Stephen Sweeney, University of Glasgow
  • Mohan Wang, Ph.D., University of Oxford
  • Professor Xuchen Wang, Harbin Engineering University
  • Professor Stefan Witte, Delft University of Technology

Face-down: Gravity's effects on cell movement



TSUKUBA, Japan, May 13, 2023 - (ACN Newswire) - Researchers at the National Institute for Materials Science (NIMS) and colleagues in Japan have developed a specially coated, light-responsive surface that helps test how the direction of gravity impacts cell movements. The findings, published in the journal Science and Technology of Advanced Materials, could lead to a better understanding of what happens to cells in people who are bedridden for prolonged periods and of the impact of gravity's direction on cancer cell migration.

The human body takes many different positions over its lifespan. Scientists wanted to find a way
to study how cell movement is impacted when the direction of gravity changes as our body positions
change. (Image created using materials from STAM Vol.24, Issue 1, Article 2206525 (2023) and
Canva.)


The special surfaces are made by coating glass slides with a combination of molecules that are responsive to light. Shining light on a central, circular area of the slide breaks up the molecules, clearing away a coating-free zone that cells can stick to. Once stabilized in this area, the scientists then use light to clear away an area surrounding the central circle. This encourages the cells to move in an outward direction to fill the square. The team investigated what happens to cell movement when the slide is placed upright, with the cells lying on top and the direction of gravity impacting the cells from top to bottom. They then conducted a similar test with the slide flipped over while supported on either side so that the cells are inverted and the direction of gravity is from the bottom of the cells to their tops.

"We found that the direction of gravity hindered collective cell migration in the inverted position by reducing the number of outward-moving leader cells at cluster edges and by redistributing shape-forming filaments, composed of actin and myosin, so that they kept the cells bundled together," explains biomaterials researcher, Shimaa Abdellatef, who is a postdoc at NIMS.

The coated, light-responsive surfaces provide an advantage over currently available methods that study the impacts of gravity's direction, as they require physical contact with the surface to which cells are attached. The new approach enables remote induction of cell migration.

"We plan to apply our approach to analyse the responses of cancer cells to the direction of gravity," says NIMS nanoscientist, Jun Nakanishi, who led the study. "We expect to find differences between healthy and diseased cells, which could provide important information about cancer progression in bedridden patients."

Further information
Jun Nakanishi
National Institute for Materials Science (NIMS)
Email:NAKANISHI.Jun@nims.go.jp

Shimaa A. Abdellatef
National Institute for Materials Science (NIMS)
Email: ABDELALEEM.shimaa@nims.go.jp

Paper: https://doi.org/10.1080/14686996.2023.2206525

About Science and Technology of Advanced Materials (STAM)

Open access journal STAM publishes outstanding research articles across all aspects of materials science, including functional and structural materials, theoretical analyses, and properties of materials. https://www.tandfonline.com/STAM

Dr Yasufumi Nakamichi
STAM Publishing Director
Email: NAKAMICHI.Yasufumi@nims.go.jp

Press release distributed by Asia Research News for Science and Technology of Advanced Materials.

Source: Science and Technology of Advanced Materials

Copyright 2023 ACN Newswire . All rights reserved.

Stock Quote API & Stock News API supplied by www.cloudquote.io
Quotes delayed at least 20 minutes.
By accessing this page, you agree to the following
Privacy Policy and Terms Of Service.