Laser Focus World is an industry bedrock—first published in 1965 and still going strong. We publish original articles about cutting-edge advances in lasers, optics, photonics, sensors, and quantum technologies, as well as test and measurement, and the shift currently underway to usher in the photonic integrated circuits, optical interconnects, and copackaged electronics and photonics to deliver the speed and efficiency essential for data centers of the future.

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Editorial Advisory Board

  • Professor Andrea M. Armani, University of Southern California
  • Ruti Ben-Shlomi, Ph.D., LightSolver
  • James Butler, Ph.D., Hamamatsu
  • Natalie Fardian-Melamed, Ph.D., Columbia University
  • Justin Sigley, Ph.D., AmeriCOM
  • Professor Birgit Stiller, Max Planck Institute for the Science of Light, and Leibniz University of Hannover
  • Professor Stephen Sweeney, University of Glasgow
  • Mohan Wang, Ph.D., University of Oxford
  • Professor Xuchen Wang, Harbin Engineering University
  • Professor Stefan Witte, Delft University of Technology

The only FDA-approved nasal spray medication proven to reduce symptoms in people living with treatment-resistant depression

(BPT) - Clinical depression or major depressive disorder (MDD) is one of the most common mental health disorders, with almost 21 million adults in the United States having experienced at least one major depressive episode in 2020.1 Even though it is one of the leading causes of disability in the US, an estimated one-third of US adults living with MDD do not respond adequately to two different antidepressants during the same depressive episode, often defined as treatment-resistant depression (TRD).2

For these patients, there are treatments available that are backed by safety and efficacy data, like SPRAVATO® (esketamine) CIII nasal spray, which received FDA approval to treat adults with TRD and to treat depressive symptoms in adults with MDD with acute suicidal thoughts or actions, in combination with an oral antidepressant.3

Patient safety is a top priority for Johnson & Johnson. This is why Johnson & Johnson collaborated with the U.S. FDA to establish a Risk Evaluation and Mitigation Strategy (REMS) program for SPRAVATO®, implementing stringent safety and post-administration protocols.3

SPRAVATO® is derived from ketamine3; however, it's important to note that it is distinctly different from ketamine. Learn more about the proven safety and efficacy of SPRAVATO® and how it is different than ketamine in the infographic below.


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References:

  1. National Institute of Mental Health. Major depression. Accessed July 15, 2024. https://www.nimh.nih.gov/health/statistics/major-depression
  2. Agency for Healthcare Research and Quality. Definition of treatment-resistant depression in the Medicare population. Accessed July 15, 2024. https://www.ncbi.nlm.nih.gov/books/NBK526366/pdf/Bookshelf_NBK526366.pdf
  3. SPRAVATO® [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc.

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