About Us

Laser Focus World is an industry bedrock—first published in 1965 and still going strong. We publish original articles about cutting-edge advances in lasers, optics, photonics, sensors, and quantum technologies, as well as test and measurement, and the shift currently underway to usher in the photonic integrated circuits, optical interconnects, and copackaged electronics and photonics to deliver the speed and efficiency essential for data centers of the future.

Our 80,000 qualified print subscribers—and 130,000 12-month engaged online audience—trust us to dive in and provide original journalism you won’t find elsewhere covering key emerging areas such as laser-driven inertial confinement fusion, lasers in space, integrated photonics, chipscale lasers, LiDAR, metasurfaces, high-energy laser weaponry, photonic crystals, and quantum computing/sensors/communications. We cover the innovations driving these markets.

Laser Focus World is part of Endeavor Business Media, a division of EndeavorB2B.

Laser Focus World Membership

Never miss any articles, videos, podcasts, or webinars by signing up for membership access to Laser Focus World online. You can manage your preferences all in one place—and provide our editorial team with your valued feedback.

Magazine Subscription

Can you subscribe to receive our print issue for free? Yes, you sure can!

Newsletter Subscription

A Laser Focus World newsletter subscription is free to qualified professionals:

The Daily Beam

Showcases the newest content from Laser Focus World, including photonics- and optics-based applications, components, research, and trends. (Daily)

Product Watch

The latest in products within the photonics industry. (9x per year)

Bio & Life Sciences Product Watch

The latest in products within the biophotonics industry. (4x per year)

Laser Processing Product Watch

The latest in products within the laser processing industry. (3x per year)

Get Published!

If you’d like to write an article for us, reach out with a short pitch to Sally Cole Johnson: [email protected]. We love to hear from you.

Photonics Hot List

Laser Focus World produces a video newscast that gives a peek into what’s happening in the world of photonics.

Following the Photons: A Photonics Podcast

Following the Photons: A Photonics Podcast dives deep into the fascinating world of photonics. Our weekly episodes feature interviews and discussions with industry and research experts, providing valuable perspectives on the issues, technologies, and trends shaping the photonics community.

Social Media

Bluesky • Facebook • Instagram • LinkedIn • YouTube

Meet the Laser Focus World Team

Editorial

Sales

Editorial Advisory Board

  • Professor Andrea M. Armani, University of Southern California
  • Ruti Ben-Shlomi, Ph.D., LightSolver
  • James Butler, Ph.D., Hamamatsu
  • Natalie Fardian-Melamed, Ph.D., Columbia University
  • Justin Sigley, Ph.D., AmeriCOM
  • Professor Birgit Stiller, Max Planck Institute for the Science of Light, and Leibniz University of Hannover
  • Professor Stephen Sweeney, University of Glasgow
  • Mohan Wang, Ph.D., University of Oxford
  • Professor Xuchen Wang, Harbin Engineering University
  • Professor Stefan Witte, Delft University of Technology
My Watchlist
Indicators
Industrial Laser Index
Markets
Stocks
ETFs
Tools
Markets:
Overview
News
Currencies
International
Treasuries

Priovant’s Brepocitinib Poised to Address Steroid-Sparing Gap in Dermatomyositis as Rheumatologists Anticipate 2026 Launch

By: via GlobeNewswire

EXTON, PA, Oct. 10, 2025 (GLOBE NEWSWIRE) -- Rheumatologists are eagerly anticipating the potential approval of brepocitinib, Priovant Therapeutics’ dual TYK2/JAK1 inhibitor, as a near-term advance for dermatomyositis (DM). According to Spherix Global Insights’ latest Market Dynamix™: Idiopathic Inflammatory Myopathies (US) service, physicians view brepocitinib as a leading pipeline candidate to deliver on the most urgent treatment goal in IIM: safe and effective steroid sparing.

The Phase 3 VALOR study, which completed enrollment earlier this year, is designed to measure improvement using the Total Improvement Score (TIS) at one year, with steroid tapering measures built into the protocol. This feature resonates strongly with rheumatologists, who cite the persistent challenge of glucocorticoid dependence as a major barrier to long-term disease control. One physician emphasized, “We do not have good treatment options if the patient does not respond to IVIg. Many patients have difficult tapering steroids.” Brepocitinib’s once-daily oral administration, coupled with its dual mechanism of action, is seen as offering meaningful promise to shift this paradigm. Based on targeted product profile assessments, physicians project notable uptake following approval, with use concentrated among DM patients in need of durable, steroid-sparing efficacy.

Beyond dermatomyositis, Spherix’s research highlights the scale of unmet need across the wider Idiopathic Inflammatory Myopathy (IIM) spectrum. Clinically amyopathic DM (CADM), necrotizing myopathy (NM), anti-synthetase syndrome (ASyS), and inclusion body myositis (IBM) are viewed as especially underserved subtypes, with IBM consistently rated the most difficult to manage. These conditions are marked by delayed diagnosis, severe manifestations such as interstitial lung disease, and poor responses to existing regimens including IVIg, rituximab, and conventional immunosuppressants. As one rheumatologist explained, “The absence of targeted therapy for IIM — there is no treatment that specifically treats IIM. We only use broad spectrum corticosteroids, immunosuppressive agents, and/or IVIg.”

Even when effective therapies are available, physicians report barriers related to insurance approvals and access. “Coverage is important in terms of how quickly I can get the patient on the medication. There were some patients where I had to fight insurance for months to get rituximab. So that's just not a reasonable amount of time for them to wait,” noted one rheumatologist. Such challenges reinforce the importance of not only developing new agents but also ensuring practical delivery and equitable patient access.

If brepocitinib is approved, Spherix will closely monitor rheumatologists’ early experiences, adoption trends, and market dynamics through its Launch Dynamix™ service. This syndicated research program provides real-time insights into physician uptake, patient candidacy, payer access, and competitive positioning during the critical first 18 months post-launch, ensuring biopharma stakeholders remain informed as brepocitinib enters clinical practice.

Taken together, the findings suggest that brepocitinib may soon represent the first tangible advance in IIM in years, with potential to reshape care for DM in particular. Yet the broader IIM population remains in urgent need of innovation, underscoring that while 2026 may mark a turning point, the journey toward comprehensive solutions for this complex disease spectrum is only beginning.

Market Dynamix™ is an independent service providing analysis of markets anticipated to experience a paradigm shift within the next three to five years. Insights highlight market size, current treatment approaches, unmet needs, and expert opinions on the likely disruption introduced by pipeline agents.

Launch Dynamix™ is an independent service providing monthly benchmarking of newly launched products for the first eighteen months of commercial availability, augmented by a quarterly deep dive into promotional activity, barriers to uptake, and patient types gravitating to the launch brand.

About Spherix Global Insights    

Spherix is a leading independent market intelligence and advisory firm that delivers commercial value to the global life sciences industry, across the brand lifecycle.    

The seasoned team of Spherix experts provides an unbiased and holistic view of the landscape within rapidly evolving specialty markets, including dermatology, gastroenterology, rheumatology, nephrology, neurology, ophthalmology, and hematology. Spherix clients stay ahead of the curve with the perspective of the extensive Spherix Physician Community.    

As a trusted advisor and industry thought leader, Spherix’s unparalleled market insights and advisory services empower clients to make better decisions and unlock opportunities for growth.    

To learn more about Spherix Global Insights, visit spherixglobalinsights.com or connect through LinkedIn.     

For more details on Spherix’s primary market research reports and interactive dashboard offerings, visit or register here: https://clientportal.spherixglobalinsights.com     

NOTICE: All company, brand or product names in this press release are trademarks of their respective holders. The findings and analysis addressed within are based on Spherix Global Insight’s analysis and do not imply a relationship with or endorsement of the companies or brands mentioned in this press release. 


Lynn Price, Rheumatology Franchise Head  
Spherix Global Insights
4848794284
lynn.price@spherixglobalinsights.com

More News

View More
FICO’s Big Dip Could Be the Best Buying Chance of the Year
Via MarketBeat
Tickers EFX FICO
D-Wave: Reevaluating the Short Seller’s Case After the Downgrade
Via MarketBeat
Tickers QBTS RGTI
Datavault: A Speculative AI Play, But Beware of Volatility
Via MarketBeat
Topics Artificial Intelligence
Tickers DVLT IBM SCLX
Traders Are Piling Into Suncor Call Options—Should You?
Via MarketBeat
Topics World Trade
Tickers SU
Delta Air Lines Stock Looks Ready to Fly to New Highs
Via MarketBeat
Tickers DAL
Stock Quote API & Stock News API supplied by www.cloudquote.io
Quotes delayed at least 20 minutes.
By accessing this page, you agree to the following
Privacy Policy and Terms Of Service.