• On the global stage, the Cancer Atlas estimates a dramatic rise in cancer cases, adding urgency to the need for therapeutic innovation
• Oncotelic’s mission focuses on developing first-in-class RNA therapeutics and small-molecule drugs to serve high-unmet-need cancers and rare pediatric diseases
• This year, the company achieved a major milestone by successfully completing a phase 1 clinical trial evaluating OT-101 combining Interleukin-2

In a landscape where cancer and underserved diseases continue to devastate millions, the demand for groundbreaking RNA-based, immunotherapeutic, and targeted treatments has never been more urgent. Oncotelic Therapeutics (OTCQB: OTLC) is answering this call with pioneering RNA candidates and strategic programs aimed at some of the most lethal and overlooked cancers.

The global cancer burden is both vast and growing. In the United States alone, an estimated 2,041,910 new cancer cases and 618,120 cancer-related deaths are projected for 2025, including conditions such as lung, breast, prostate and colorectal cancers that dominate incidence and mortality statistics (ibn.fm/M7MFi). On the global stage, the Cancer Atlas estimates a dramatic rise in cancer cases, from…

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NOTE TO INVESTORS: The latest news and updates relating to OTLC are available in the company’s newsroom at ibn.fm/OTLC

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