3 Unprofitable Stocks We Steer Clear Of

August 21, 2025 at 05:44 AM EDT

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Unprofitable companies face headwinds as they struggle to keep operating expenses under control. Some may be investing heavily, but the majority fail to convert spending into sustainable growth.

Finding the right unprofitable companies is difficult, which is why we started StockStory - to help you navigate the market. Keeping that in mind, here are three unprofitable companiesthat don’t make the cut and some better opportunities instead.

Marcus & Millichap (MMI)

Trailing 12-Month GAAP Operating Margin: -4.4%

Founded in 1971, Marcus & Millichap (NYSE: MMI) specializes in commercial real estate investment sales, financing, research, and advisory services.

Why Should You Dump MMI?

Products and services fail to spark excitement with consumers, as seen in its flat sales over the last five years
Lacking free cash flow generation means it has few chances to reinvest for growth, repurchase shares, or distribute capital
Eroding returns on capital suggest its historical profit centers are aging

At $30.92 per share, Marcus & Millichap trades at 238.2x forward P/E. Dive into our free research report to see why there are better opportunities than MMI.

iRhythm (IRTC)

Trailing 12-Month GAAP Operating Margin: -16.1%

Pioneering the shift from bulky, short-term heart monitors to sleek, wire-free patches, iRhythm Technologies (NASDAQ: IRTC) provides wearable cardiac monitoring devices and AI-powered analysis services that help physicians detect and diagnose heart rhythm disorders.

Why Are We Cautious About IRTC?

Revenue base of $657.2 million puts it at a disadvantage compared to larger competitors exhibiting economies of scale
Negative free cash flow raises questions about the return timeline for its investments
High net-debt-to-EBITDA ratio could force the company to raise capital at unfavorable terms if market conditions deteriorate

iRhythm’s stock price of $164 implies a valuation ratio of 75.4x forward EV-to-EBITDA. Read our free research report to see why you should think twice about including IRTC in your portfolio.

Repligen (RGEN)

Trailing 12-Month GAAP Operating Margin: -3.5%

With over 13 strategic acquisitions since 2012 to build its comprehensive bioprocessing portfolio, Repligen (NASDAQ: RGEN) develops and manufactures specialized technologies that improve the efficiency and flexibility of biological drug manufacturing processes.

Why Do We Avoid RGEN?

Core business is underperforming as its organic revenue has disappointed over the past two years, suggesting it might need acquisitions to stimulate growth
Day-to-day expenses have swelled relative to revenue over the last five years as its adjusted operating margin fell by 16.9 percentage points
Shrinking returns on capital from an already weak position reveal that neither previous nor ongoing investments are yielding the desired results

Repligen is trading at $121.68 per share, or 64x forward P/E. Check out our free in-depth research report to learn more about why RGEN doesn’t pass our bar.

Stocks We Like More

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3 Unprofitable Stocks We Steer Clear Of

Marcus & Millichap (MMI)

iRhythm (IRTC)

Repligen (RGEN)

Stocks We Like More

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