Kansas City, KS - A new study published today explores the revolutionary potential of artificial intelligence (AI) in diagnosing oral squamous cell carcinoma (OSCC), a common but often late-diagnosed cancer that affects the oral cavity. The study, titled “Role of Artificial Intelligence in the Diagnosis of Oral Squamous Cell Carcinoma: A Systematic Review,” was conducted by Tanay Chowdhury, Pratik Kasralikar, Abdul Aleem Syed, Ramakrishna Tumati, Sandipkumar Patel, and Dheeraj Kommineni. These researchers are paving the way forward for advanced research alongside leading researchers in the fields of oncology and artificial intelligence, including Dr. Farouk Mutai and Dr. Sarah Ndirangu. These researchers are renowned for their groundbreaking work in using AI to improve cancer diagnosis, particularly in resource-limited settings.
Oral squamous cell carcinoma is responsible for more than 10,000 cancer-related deaths each year in the United States, with over 50,000 new cases diagnosed annually. Early detection of OSCC is crucial for successful treatment and improving survival rates. However, this type of cancer is often diagnosed at later stages, where treatment options are limited, and the prognosis is poor. The systematic review reveals that AI, specifically machine learning algorithms, can aid in the early diagnosis of OSCC by analyzing medical images, biopsies, and patient data more efficiently than traditional methods, potentially saving the lives of thousands of Americans each year.
"The ability of AI to assist in diagnosing oral cancers at earlier stages could significantly improve survival outcomes," said Mr. Lukas Meier, Senior Journalist at Alpine Vision Media. “This research not only highlights the potential of AI but also emphasizes the importance of integrating these technologies into clinical practice, especially in resource-limited settings where access to specialized care may be scarce.” Dr. Farouk Mutai, a leading oncologist from Uganda, and Dr. Sarah Ndirangu, an AI researcher and oncologist based in Kenya, have been instrumental in the development of AI-driven diagnostic tools for cancer detection. Their work has paved the way for AI to be integrated into cancer care in regions with limited access to healthcare specialists. Their research focuses on addressing diagnostic challenges in underserved regions and demonstrates the transformative potential of AI in improving patient outcomes.
In the United States, the economic impact of early detection could be significant. The integration of AI into OSCC diagnosis could help reduce the overall treatment expenses for OSCC patients by detecting cancers earlier, when treatment is more affordable and effective. The U.S. currently spends over $4 billion annually on the treatment of late-stage OSCC cases, and early detection powered by AI could potentially lower these costs significantly, while also improving survival rates. The systematic review suggests that AI-powered diagnostic tools could play a critical role in overcoming current limitations in diagnosing OSCC, particularly in developing regions. It calls for further research and investment in AI technologies to enhance diagnostic capabilities worldwide.
Citation: Chowdhury T, Kasralikar P, Aleem Syed A, et al. (April 06, 2025) Role of Artificial Intelligence in the Diagnosis of Oral Squamous Cell Carcinoma: A Systematic Review. Cureus 17(4): e81800. DOI 10.7759/cureus.81800
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