Vizgen, Inc., a spatial multi-omics innovator accelerating biological discovery and new drug development, today announced that it will present new spatial multi-omics data at the Society for Immunotherapy of Cancer (SITC) 40^th Annual Meeting on November 7-10, 2025 in National Harbor, Maryland. The company will showcase how researchers can generate a combination of high-quality RNA and protein data via Vizgen’s bioinformatics technology.

Vizgen combined results from MERFISH 2.0™ gene expression data generated on the MERSCOPE Ultra™ with data collected from InSituPlex^® (ISP) multiplex immunofluorescence (mIF) in sequential sections to decode the complexity of the tumor-immune microenvironment (TiME). In its session on November 7^th at SITC, Vizgen will delve into how to co-register two established high-quality datasets to fuel multi-omic research.

“Vizgen is empowering researchers to use the power of spatial multi-omics to gain valuable new insights, and we’re excited to share the latest data at SITC to demonstrate what is possible to significantly advance research,” said Jiang He, VP & Portfolio Owner, Reagents & Sci. Affairs, at Vizgen. “The scientific community in attendance at SITC 2025 will get a first look at data that improves the understanding of the tumor-immune microenvironment through a unified approach with spatial multi-omics. Vizgen offers a complete solution to study the tumor microenvironment.”

POSTERS

Details of the posters at the Gaylord National Resort and Convention Center at SITC 2025 are as follows:

Abstract Number: 101

Title: Combining Vizgen’s MERSCOPE gene expression profiling and InSituPlex multiplex immunofluorescence (mIF) to reveal functional compartmentalization within the tumor microenvironment (TME)

Session Date: Friday, November 7, 2025

Session Time: Between 12:15 p.m. and 1:45 p.m. ET (Lunch session) and between 5:35 p.m. and 7 p.m. (PM reception)

Presenter: Angela Vasaturo, Director of Scientific Affairs at Vizgen

Abstract Number: 102

Title: New developments in spatial transcriptomics using MERFISH 2.0 unlock insights into the tumor microenvironment

Session Date: Saturday, November 8, 2025

Session Time: Between 12:15 p.m. and 1:45 p.m. ET (Lunch session) and between 5:35 p.m. and 7 p.m. (PM reception)

Presenter: Amanda Burke, PhD, Field Application Scientist, Vizgen

Abstract Number: 84

Title: Enabling scalable tumor microenvironment (TME) profiling with 8-plex InSituPlex multiplex immunofluorescence (mIF) on ZEISS Axioscan 7 spatial biology

Session Date: Saturday, November 8, 2025

Session Time: Between 12:15 p.m. and 1:45 p.m. ET (Lunch session) and between 5:10 p.m. and 6:35 p.m. (PM reception)

Presenter: Kevin Hwang, Ph.D., Senior Scientist, Research at Vizgen

Abstract Number: 88

Title: Establishing a robust and reproducible automated mIF workflow for spatial biology using ZEISS SlideStream and Ultivue by Vizgen’s InSituPlex assays

Session Date: Saturday, November 8, 2025

Session Time: Between 12:15 p.m. and 1:45 p.m. ET (Lunch session) and between 5:35 p.m. and 7 p.m. (PM reception)

Presenter: Cassandra Kysilovsky, Ph.D., Associate Scientist at Vizgen

In exhibit hall booth #838, Vizgen representatives will be showcasing a spatial multi-omic workflow that combines spatial transcriptomics, spatial proteomics, and AI-enhanced data science.

Abstracts

To view abstracts, visit: https://www.sitcancer.org/2025/abstracts/titles-and-publications

About Vizgen^®

Vizgen is at the forefront of spatial biology and multi-omics innovation. Through its pioneering MERFISH 2.0™ technology and MERSCOPE^® Platform for in situ single-cell spatial genomics and its high-fidelity InSituPlex^® protein assays and AI-driven STARVUE™ spatial image analysis technology, Vizgen delivers unmatched tools that enable researchers to uncover deep insights into human biology and achieve breakthroughs in understanding mechanisms of complex diseases, including neurodegenerative disorders and cancer. MERFISH and InSituPlex are for research use only. Vizgen is headquartered in Cambridge, Massachusetts, and can be found online at www.vizgen.com and www.ultivue.com. Connect on social media Twitter, LinkedIn and Facebook.

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