About Cabling Installation & Maintenance

Our mission: Bringing practical business and technical intelligence to today's structured cabling professionals

For more than 30 years, Cabling Installation & Maintenance has provided useful, practical information to professionals responsible for the specification, design, installation and management of structured cabling systems serving enterprise, data center and other environments. These professionals are challenged to stay informed of constantly evolving standards, system-design and installation approaches, product and system capabilities, technologies, as well as applications that rely on high-performance structured cabling systems. Our editors synthesize these complex issues into multiple information products. This portfolio of information products provides concrete detail that improves the efficiency of day-to-day operations, and equips cabling professionals with the perspective that enables strategic planning for networks’ optimum long-term performance.

Throughout our annual magazine, weekly email newsletters and 24/7/365 website, Cabling Installation & Maintenance digs into the essential topics our audience focuses on.

  • Design, Installation and Testing: We explain the bottom-up design of cabling systems, from case histories of actual projects to solutions for specific problems or aspects of the design process. We also look at specific installations using a case-history approach to highlight challenging problems, solutions and unique features. Additionally, we examine evolving test-and-measurement technologies and techniques designed to address the standards-governed and practical-use performance requirements of cabling systems.
  • Technology: We evaluate product innovations and technology trends as they impact a particular product class through interviews with manufacturers, installers and users, as well as contributed articles from subject-matter experts.
  • Data Center: Cabling Installation & Maintenance takes an in-depth look at design and installation workmanship issues as well as the unique technology being deployed specifically for data centers.
  • Physical Security: Focusing on the areas in which security and IT—and the infrastructure for both—interlock and overlap, we pay specific attention to Internet Protocol’s influence over the development of security applications.
  • Standards: Tracking the activities of North American and international standards-making organizations, we provide updates on specifications that are in-progress, looking forward to how they will affect cabling-system design and installation. We also produce articles explaining the practical aspects of designing and installing cabling systems in accordance with the specifications of established standards.

Cabling Installation & Maintenance is published by Endeavor Business Media, a division of EndeavorB2B.

Contact Cabling Installation & Maintenance

Editorial

Patrick McLaughlin

Serena Aburahma

Advertising and Sponsorship Sales

Peter Fretty - Vice President, Market Leader

Tim Carli - Business Development Manager

Brayden Hudspeth - Sales Development Representative

Subscriptions and Memberships

Subscribe to our newsletters and manage your subscriptions

Feedback/Problems

Send a message to our general in-box

 

BioRestorative Therapies' Drug Candidate BRTX-100 Passes Safety Test With Flying Colors, Moves Ahead With Phase 2 And Looks To Expand Pipeline Opportunities

MELVILLE, NY / ACCESSWIRE / July 7, 2023 / BioRestorative Therapies Inc. (NASDAQ: BRTX) has received a unanimous recommendation to proceed in its Phase 2 clinical trial for chronic lumbar disc disease, BRTX-100. The independent review body Data Safety Monitoring Board (DSMB) which is overseeing dose and safety related issues during the course of the trial approved the trial's continuation with no changes to the current version of the protocol.

BioRestorative Therapies, Inc., Friday, July 7, 2023, Press release picture

This is the highest distinction given by the DSMB, which can recommend continuation without changes to the protocol, continuation with changes, or a suspension or termination of the trial. BioRestorative received unanimous approval from the DSMB to continue with no changes.

The safety data reviewed by the DSMB to determine if there was any toxicity related to dosing was taken from three patients who received BRTX-100, an injection of 40,000,000 hypoxic cultured mesenchymal stem cells formulated with autologous platelet lysate, while a fourth received an injection of saline placebo. There were no severe adverse events that were correlated to dose limiting toxicity( DLTs). The blinded results showed some of the patients experienced a reduction of pain and an increase in function.

BioRestorative Looks Ahead

BioRestorative can now begin moving ahead with the next stage of the trial. The study will start the open enrollment of the balance of the 99 patients. BRTX-100 is a cellular therapy injection developed from autologous hypoxic cultured mesenchymal stem cells which are taken from the patient's own bone marrow and formulated with autologous platelet lysate.

Now that there is initial confirmation about the drug's safety profile, the company plans to build out its platform technology. It is excited to begin examining other applications the drug may have in different parts of the body.

The company plans to advance the expansion of the platform by leveraging the safety and efficacy data from BRTX-100s trials, as well as assisting KOLs in investigator-initiated studies and small-subject studies. It will be looking at the treatment's potential indications in other avascular zones (areas in the body with little blood flow). The cervical area and the meniscus, as well as the hips, the shoulders and the extremities could be potential areas of focus.

"This unanimous recommendation of the DSMB to allow BioRestorative to proceed without any changes to the protocol represents a significant binary outcome and major milestone for the continuation of our clinical program," said Lance Alstodt, CEO of BioRestorative Therapies.

He continued, "With the safety profile of BRTX-100 now established through the DSMB process, we intend to accelerate the enrollment of the balance of our 99-patient study. In addition and more importantly, we intend to leverage the product technology platform across multiple indications further extending our pipeline opportunities."

With much to look ahead to, the company also has a stable funding position that allows it to advance through its next milestones, according to Lance. It finished Q1 of 2023 with over $12.7 million in capital.

Other companies involved in developing innovative cell therapies include Atherys, Inc., Brainstorm Therapeutics, and Mesoblast.

Read more about BioRestorative's trials and platform technology.

Featured photo by Louis Reed on Unsplash.

Contact Details

Investor Relations
ir@biorestorative.com

SOURCE: BioRestorative Therapies, Inc.



View source version on accesswire.com:
https://www.accesswire.com/766145/BioRestorative-Therapies-Drug-Candidate-BRTX-100-Passes-Safety-Test-With-Flying-Colors-Moves-Ahead-With-Phase-2-And-Looks-To-Expand-Pipeline-Opportunities

Stock Quote API & Stock News API supplied by www.cloudquote.io
Quotes delayed at least 20 minutes.
By accessing this page, you agree to the following
Privacy Policy and Terms Of Service.