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Major breakthrough in fight against resistant grass weeds

By: Syngenta via Business Wire

June 17, 2025 at 08:00 AM EDT

After more than a decade of cutting-edge research, the newest herbicide from Syngenta is recognized under a new chemical subclass
Farmers to benefit from solution to grass weeds that have evolved resistance to existing herbicides

Weeds compete with crops for resources such as water, nutrients and sunlight, and lower yields in major crops by as much as 43% (Savary, 2019). The evolution of herbicide resistance in many weed species today poses a serious and growing threat to many farmers around the world, limiting yield and – in extreme cases – destroying the value of the land. Innovation in herbicide technologies has resurged in importance and urgency, reflecting the value of such technologies in controlling weeds and improving the sustainability of farming operations.

Syngenta, a global leader in agricultural innovation, announced today that its latest weed control solution, metproxybicyclone, has been recognized under a new chemical subclass of herbicides. The decision, by the Herbicide Resistance Action Committee (HRAC) and the Weed Science Society of America (WSSA), reflects metproxybicyclone’s distinction as the fourth generation of ACCase-inhibitors, an important class of herbicides. The third generation of ACCase-inhibitors, represented by Syngenta’s leading molecule pinoxaden, was launched in 2006; the nearly two-decade long gap in ACCase subclass innovation reflects in part the extreme challenges in finding new, effective and safe solutions.

“Herbicide resistance has been officially reported in 75 countries and affects farmers of more than 100 crops; of the 273 weed species afflicted, 40 percent are grass weeds,” said Camilla Corsi, Syngenta’s Global Head of Research and Development. “At Syngenta, we push the boundaries of crop protection science to deliver solutions farmers need. Years ago, our scientists foresaw that certain grass weeds in Argentina and Brazil would likely evolve resistance to existing herbicides, and since then we’ve raced to bring a solution to market – in time to support soybean and cotton farmers who now confront this challenge.” Subject to regulatory approvals, the new herbicide is currently expected to be introduced in Argentina in 2026.

The novel herbicide was invented at Syngenta’s International Research Centre at Jealott’s Hill, UK. By leveraging Syngenta’s extensive expertise in ACCase-inhibitors and state-of-the-art computer modelling, scientists precisely designed a new subclass of herbicide capable of controlling grass weeds that had evolved resistance to herbicides such as glyphosate and clethodim, while optimizing the molecule’s sustainability profile. The approach reflects Syngenta’s “Safer by Design” research philosophy that guides Syngenta’s efforts in delivering higher yields while lowering the impact to the planet through more sustainable technologies.

Syngenta is widely regarded for its leading pipeline of innovative agricultural solutions. Its portfolio of crop protection solutions includes products based on ADEPIDYN® technology, PLINAZOLIN® technology and TYMIRIUM® technology, as well as a wide and expanding array of biological and digital solutions.

About Syngenta

Syngenta is a global leader in agricultural innovation with a presence in more than 90 countries. Syngenta is focused on developing technologies and farming practices that empower farmers, so they can make the transformation required to feed the world’s population while preserving our planet. Its bold scientific discoveries deliver better benefits for farmers and society on a bigger scale than ever before. Guided by its Sustainability Priorities, Syngenta is developing new technologies and solutions that support farmers to grow healthier plants in healthier soil with a higher yield. Syngenta Crop Protection is headquartered in Basel, Switzerland; Syngenta Seeds is headquartered in the United States. Read our stories and follow us on LinkedIn, Instagram & X.

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Cautionary Statement Regarding Forward-Looking Statements

This document may contain forward-looking statements, which can be identified by terminology such as ‘expect’, ‘would’, ‘will’, ‘potential’, ‘plans’, ‘prospects’, ‘estimated’, ‘aiming’, ‘on track’ and similar expressions. Such statements may be subject to risks and uncertainties that could cause the actual results to differ materially from these statements. For Syngenta, such risks and uncertainties include risks relating to legal proceedings, regulatory approvals, new product development, increasing competition, customer credit risk, general economic and market conditions, compliance and remediation, intellectual property rights, implementation of organizational changes, impairment of intangible assets, consumer perceptions of genetically modified crops and organisms or crop protection chemicals, climatic variations, fluctuations in exchange rates and/or commodity prices, single source supply arrangements, political uncertainty, natural disasters, and breaches of data security or other disruptions of information technology. Syngenta assumes no obligation to update forward-looking statements to reflect actual results, changed assumptions or other factors.

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View source version on businesswire.com: https://www.businesswire.com/news/home/20250617226475/en/

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Major breakthrough in fight against resistant grass weeds

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