Clinical Evidence for Paragonix medical devices presented in multiple seminars and posters at Denver’s ISHLT 2023 Annual Meeting

Paragonix Technologies, Inc., a leading organ transplant company, is dedicated to advancing the science of modern transplantation by conducting novel research powered by the GUARDIAN registries - the largest clinical databases specifically focused on the preservation of donor organs during transport. Participating investigators will present research on a variety of factors - including organ preservation, transportation, and characteristics of both donors and recipients - at the 2023 International Society for Heart and Lung Transplantation 43rd Annual Meeting and Scientific Sessions, held in late April at the Colorado Conference Center in Denver, CO.

“Together with our clinical investigators, we have built the largest global thoracic registry dedicated to the scientific study of organ preservation. We are indebted to our clinical investigators who share our vision and are questioning old practices in organ transport,” said Dr. Lisa Anderson, President and CEO of Paragonix. “The ISHLT Annual Meeting is one of our industry's premier scientific gatherings and it is an honor to be able to share our tremendous research efforts with its attendees.”

Clinical investigators will be sharing data related to Paragonix technology in six oral presentations, eight mini-oral presentations, and multiple posters during the event, including:

Oral Presentations

• Recipient Outcomes with Extended Criteria Donors: An Analysis of the Guardian Heart Registry
  • April 19, 2023, 5:00 PM - 5:10 PM – Rooms 205 – 207
• Not Too Warm, Not Too Cold: Real-World Multi-Center Outcomes with Elevated Hypothermic Preservation of Donor Lungs
  • April 20, 2023, 10:15 AM - 10:25 AM – Rooms 201 – 203
• Results from Over 800 Transplant Recipients Enrolled in the Guardian Heart Registry
  • April 21, 2023, 10:30 AM - 10:40 AM – Rooms 405 – 407
• Validating the 2014 Consensus Primary Graft Definition: An Analysis on the 1,056 Patients from the Multi-Center Guardian Registry
  • April 21, 2023, 2:30 PM - 2:40 PM – Rooms 205 – 207
• Pediatric Experience Using the SherpaPak Cardiac Transport System: A Subgroup Analysis of the Guardian Heart Registry
  • April 23, 2023, 8:15 AM - 8:25 AM – Rooms 205 – 207

Mini-Oral Presentations

• Ice is Not 4c: Thermodynamic Characterization of Lungs and Hearts Preserved on Ice
  • April 19, 2023, 5:42 PM - 5:46 PM – Rooms 401 – 404
• Leveraging Advanced Hypothermic Preservation to Achieve Transplant Program Goals
  • April 21, 2023, 5:00 PM - 5:04 PM – 205 – 207
• Role of SherpaPak in Donors with Drug Overdose and Long Ischemic Times
  • April 21, 2023, 5:24 PM - 5:28 PM – 205 – 207
• SherpaPak Reduces MCS Use Post Heart Transplant in Long Donor Down and Ischemic Times
  • April 21, 2023, 5:30 PM - 5:34 PM – Rooms 205 – 207
• Can Controlled Hypothermic Preservation Provide Clinical Benefits in the Setting of Shorter Ischemic Times Prior to Heart Transplant
  • April 21, 2023, 5:54 PM - 5:58 PM – Rooms 205 – 207

Poster Presentations

• How Long can we go? Redefining the Upper Limit of Ischemic Times for Hypothermic Donor Heart Preservation
  • April 19, 2023, 6:30 PM – 7:30 PM – Mile High Ballroom
• Outcomes in Children and Young Adults with Congenital Heart Disease Undergoing Transplant: A Subgroup Analysis of the GUARDIAN Heart Registry
  • April 19, 2023, 6:30 PM - 7:30 PM – Mile High Ballroom
• Improved Outcomes in Older Recipients Undergoing Transplant Using the SherpaPak System: A Subgroup Analysis of the GUARDIAN Heart Registry
  • April 19, 2023, 6:30 PM - 7:30 PM – Mile High Ballroom

Additionally, Paragonix will be hosting two Industry Symposia on Advanced Organ Preservation research at the conference. On Thursday, April 20^th, at 11:30 AM in rooms 501 – 504, Paragonix will be presenting a symposium titled Beyond Limits: Harnessing Advanced Preservation to Enhance Donor Lung Procurement. The event will feature leading experts in the field as they discuss the latest breakthroughs and innovations in preserving lung viability for transplantation.

On Friday, April 21^st, at 11:30 AM in rooms 501 – 504, Paragonix will be hosting a heart symposium titled Resetting the Standard: Impact of Advanced Heart Preservation on Program Growth. The event will host top industry experts who will delve into the science behind Paragonix's innovative solutions, discuss their use of advanced organ preservation, and present the impact of advanced preservation on patient outcomes. Both of these events are Non-CME industry events presented by Paragonix Technologies.

To visit the Paragonix Technologies exhibit and meet members of their team at ISHLT, visit booth #301. For more information about Paragonix, visit www.paragonix.com.

About Paragonix Technologies

Paragonix Technologies is a leading developer, manufacturer, and service provider in the organ transplant industry, establishing a novel approach to preservation that represents a significant improvement over the traditional standard of care.

Paragonix Advanced Organ Preservation devices combine clinically-proven, stable cooling techniques with digital tracking and monitoring technologies to provide clinicians complete control and oversight throughout the donor organ journey. The clinical impact of Paragonix preservation technology is reinforced by the GUARDIAN clinical registries, the largest database of organ preservation data in the world that analyzes post-transplant outcomes in transplant recipients. For more information, visit www.paragonix.com.

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