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Why Vertex Pharmaceuticals (VRTX) Stock Is Trading Lower Today

VRTX Cover Image

What Happened?

Shares of biotech company Vertex Pharmaceuticals (NASDAQ: VRTX) fell 17.4% in the afternoon session after the company announced its experimental pain drug, VX-993, failed a key mid-stage clinical trial. The company’s experimental non-opioid painkiller, VX-993, failed to achieve a statistically significant pain reduction compared to a placebo in a mid-stage study. The trial involved patients who had undergone bunionectomy surgery. Following the failure, Vertex Pharmaceuticals stated it would stop the development of VX-993 as a standalone treatment for acute pain. This setback in the company's drug pipeline overshadowed its recently reported strong second-quarter financial results. The news also compounded concerns after the company revealed that expanding the approval for another pain medicine, Journavx, also faced regulatory hurdles.

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What Is The Market Telling Us

Vertex Pharmaceuticals’s shares are not very volatile and have only had 4 moves greater than 5% over the last year. Moves this big are rare for Vertex Pharmaceuticals and indicate this news significantly impacted the market’s perception of the business.

Vertex Pharmaceuticals is down 7.6% since the beginning of the year, and at $375.04 per share, it is trading 27.4% below its 52-week high of $516.74 from November 2024. Investors who bought $1,000 worth of Vertex Pharmaceuticals’s shares 5 years ago would now be looking at an investment worth $1,373.

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